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Traditional Chinese medicine composition for treating liver cirrhosis and fibrosis and preparation method thereof

A composition and fibrosis technology, applied in the directions of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc., can solve the problems of liver fibrosis without ideal toxicity, difficult to determine curative effect, and high incidence of liver cirrhosis

Inactive Publication Date: 2012-11-14
HUANGHUAI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a kind of traditional Chinese medicine composition for treating liver cirrhosis and fibrosis in view of defects such as high incidence of liver cirrhosis, no ideal effective drug treatment for liver fibrosis, high toxicity of western medicines, and difficulty in determining curative effect. Preparation

Method used

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  • Traditional Chinese medicine composition for treating liver cirrhosis and fibrosis and preparation method thereof
  • Traditional Chinese medicine composition for treating liver cirrhosis and fibrosis and preparation method thereof
  • Traditional Chinese medicine composition for treating liver cirrhosis and fibrosis and preparation method thereof

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Effect test

Embodiment 1

[0147] The present invention is used to treat the traditional Chinese medicine composition of liver cirrhosis and fibrosis, expressed in parts by weight, and the crude drug of said Chinese medicine composition is composed of 12 parts of Danshen, 10 parts of black bean, 12 parts of Radix Paeoniae Rubra, 10 parts of Ophiopogon japonicus, and 12 parts of Radix Astragali , Codonopsis 18 parts, Angelica 12 parts, Turtle Shell 12 parts, Curcuma 10 parts, Achyranthes bidentata 12 parts, Chinese yam 12 parts, Polygonum cuspidatum 12 parts, Snake Grass 12 parts, Amomum 9 parts and Zhi Licorice 9 parts.

[0148] The dosage form of the above-mentioned traditional Chinese medicine composition for treating liver cirrhosis and fibrosis of the present invention can be decoction, powder or pill, and the preparation method of the decoction, powder and pill thereof is detailed in the third part of the content of the invention, and will not be described in detail here .

Embodiment 2

[0149] Embodiment 2: basically the same as Embodiment 1, the difference is:

[0150] The present invention is used to treat the Chinese medicine composition of liver cirrhosis and fibrosis, expressed in parts by weight. The crude drug of said Chinese medicine composition consists of 15 parts of Salvia miltiorrhiza, 9 parts of black bean, 10 parts of red peony root, 12 parts of Radix Ophiopogon japonicus, 20 parts of Radix Astragali , Codonopsis 15 parts, Angelica 15 parts, Turtle Shell 10 parts, Curcuma 9 parts, Achyranthes bidentata 10 parts, Chinese yam 10 parts, Polygonum cuspidatum 10 parts, Snake Grass 10 parts, Amomum 10 parts and Zhi Licorice 7 parts.

Embodiment 3

[0151] Embodiment 3: basically the same as Embodiment 1, the difference is:

[0152] The present invention is used to treat the Chinese medicine composition of liver cirrhosis and fibrosis, expressed in parts by weight. The raw material of the Chinese medicine composition consists of 9 parts of Salvia miltiorrhiza, 7 parts of black bean, 6 parts of Radix Paeoniae Rubra, 8 parts of Ophiopogon japonicus, and 15 parts of Radix Astragali , 12 parts of Codonopsis, 8 parts of Angelica, 13 parts of Turtle Shell, 12 parts of Curcuma, 9 parts of Achyranthes bidentata, 11 parts of Chinese Yam, 8 parts of Polygonum cuspidatum, 8 parts of Snake Grass, 6 parts of Amomum japonicus and 6 parts of Zhigancao.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating liver cirrhosis and fibrosis and a preparation method thereof. The traditional Chinese medicine composition is mainly prepared by the bulk drugs of radix salviae miltiorrhizae, black soya bean, red paeony root, ophiopogon root, astragalus root, radix codonopsis pilosulae, angelica, carapax amydae, rhizoma zedoariae, twotooth achyranthes root, Chinese yam, giant knotweed, hedyotis diffusa, fructus amomi and honey-fried licorice root. The prescription disclosed by the invention is complete in the matching of a monarch, a minister, an adjuvant and a conductant drug, is excellent in the efficacy of drugs, is flexible in application and has the comparatively obvious characteristic of traditional Chinese medicine. The traditional Chinese medicine composition disclosed by the invention has the actions of resisting the fibrosis, resisting hepatitis B virus (HBV) replication, improving the liver function, regulating the blood circulation of the liver, reinforcing the liver, softening hard masses, strengthening the spleen and the like; and the traditional Chinese medicine composition also has the actions of lowering the portal pressure, reducing the thickness of the spleen and improving the liver function. The traditional Chinese medicine composition disclosed by the invention has an obvious curative effect in the therapeutic action to the liver cirrhosis and fibrosis. In addition, the traditional Chinese medicine composition disclosed by the invention has an obvious action of resisting the liver cirrhosis and fibrosis of children.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating liver cirrhosis and fibrosis and a preparation method thereof. Background technique [0002] Liver fibrosis and cirrhosis are chronic progressive liver diseases characterized by excessive collagen fiber deposition in the liver caused by liver inflammation or direct toxic injury. Liver fibrosis can lead to hepatic sinusoidal capillarization, increased sinusoidal pressure, and intrahepatic microcirculation disturbance, affecting the material exchange between blood and liver cells, which in turn aggravates liver cell damage, further develops liver fibrosis and forms a vicious circle. Liver cirrhosis is based on diffuse liver fibrosis. Due to the compensatory nodular regeneration of liver cells and the regeneration of connective tissue, changes in liver tissue structure and reduction of functional liver cells lead to...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/16A61P31/14A61K35/56A61K35/586
Inventor 张小兆杨铁骊潘胜军张小方钱国强党真
Owner HUANGHUAI UNIV
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