Medicine loading type contact lens and preparation method thereof

一种隐形眼镜、载药的技术,应用在医药配方、眼镜/护目镜、眼科治疗等方向,能够解决眼睛干涩刺痛、副作用、佩戴不便等问题,达到减少漏药情形、副作用机率低、制程简单的效果

Active Publication Date: 2012-11-14
SPRING FOUND OF NCTU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, although the materials for making contact lenses have been greatly improved, the allergy problem caused by wearing contact lenses still exists so far. Contact lens wearers often feel dry and stinging eyes due to the reduction of moisture in the contact lenses themselves; and To continue wearing contact lenses, the wearer must frequently moisten the contact lenses with a wetting solution
Furthermore, if the eyes themselves are inflamed or dry and tingling for some reason, sometimes it is necessary to order some liquid medicine or some maintenance liquids, etc., but most of the liquid medicines cannot be used when wearing contact lenses, causing inconvenience to the wearer
[0004] On the other hand, regardless of wearing contact lenses or not, when the general user uses eye drops, after the eyes are instilled with eye drops, the eye drops will be lost due to reflex actions such as blinking, tear dilution, and drainage, so that about Less than 5% of the dose is absorbed by the eyes; in addition, the drug stays in the eyes for a short time, once the drug molecules enter the blood circulation, it may cause some side effects

Method used

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  • Medicine loading type contact lens and preparation method thereof
  • Medicine loading type contact lens and preparation method thereof
  • Medicine loading type contact lens and preparation method thereof

Examples

Experimental program
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Embodiment Construction

[0027] The invention relates to a local drug delivery system (local drug delivery system), which uses a worn contact lens to deliver local drugs to achieve the purpose of medical treatment and health care. That is to say, the present invention utilizes nano-carriers with good drug coating ability and high biocompatibility to coat drug molecules and make them uniformly dispersed in contact lenses; when the contact lenses are worn on the eyes, the drug molecules It can be released slowly through the lens to achieve long-term release (>24 hours) of drug molecules into the eye tissue. Not only can it be released slowly for a long time, but it can also minimize the loss of drugs and the probability of side effects on the human body.

[0028] The drug-loaded contact lens of the present invention mainly includes a contact lens body, which at least includes an amphoteric hybrid nanocarrier, and the amphoteric hybrid nanocarrier is loaded with hydrophilic or hydrophobic drug molecules, ...

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PUM

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Abstract

The invention refers to a medicine loading type contact lens and a preparation method thereof. The medicine loading type contact lens is provided with a contact lens body which at least comprises a bipolar mixing nanometer carriers provided with medicine molecules. According to the utility model, a cladding type and a medicine dipping type medicine loading type contact lens are respectively prepared by means of light or heat sensitivity difference of the medicine molecules. According to the utility model, the bipolar mixing nanometer carriers with good medicine cladding ability and high biological compatibility are utilized to clad the medicine molecules to make the medicine molecules slowly release into eye tissue for a long time and reduce medicine loss and the probability of generating side effects on human bodies to a lowest degree to arrive the purpose of medical and health care.

Description

technical field [0001] The invention relates to a contact lens related technology, in particular to a drug-loaded contact lens capable of local drug release for long-term release of drug molecules and a preparation method thereof. Background technique [0002] For a long time, the damage and degeneration of eyesight has plagued people. For the damage of eyesight, taking myopia as an example, people usually use prescription glasses or contact lenses to make their eyes see clearly; Especially for people with poor vision, contact lenses are a very convenient option. [0003] At present, contact lenses can be roughly divided into hard lenses and soft lenses, and the material of soft lenses is usually silicone hydrogels (silicone hydrogels), polyacrylamide (polyacrylamide, PAA) or polyhydroxyethyl methacrylate (PHEMA) ...and so on, the wearer has a better sense of comfort during use, and because the price is relatively cheap, it is the mainstream of the current market. However,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G02C7/04A61L31/04A61L31/02A61L31/16
CPCG02B1/043A61K9/1273A61K9/5161A61F9/00A61K9/5115A61F9/0017A61K9/0051
Inventor 刘典谟刘佩铃
Owner SPRING FOUND OF NCTU
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