Traditional Chinese medicine composition for treating Behcet diseases

A technology for Behcet's disease and a composition, applied in the field of traditional Chinese medicine compositions for treating Behcet's disease, can solve the problems of inability to meet the actual needs of Behcet's disease, poor systemic effect, not very clear, etc., and achieves low cost , Less toxic and side effects, the effect of scientific formulation

Inactive Publication Date: 2013-04-03
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern medicine is not very clear about the etiology and pathogenesis of Behcet's disease. Most of them believe that it is related to virus, immune and genetic factors. Adrenal cortex hormone, immunosuppressant and colchicine have been used in the treatment, which has great side effects and recurrence. The rate is high, and Chinese medicine is a treasure house, which has created good conditions and medicines for the treatment of diseases. However, at present, Chinese medicine uses the same treatment methods and basically the same prescriptions for clinical and experimental research. The limitations are good and systematic. The effect is poor, and the published "a pharmaceutical composition for the treatment of oral ulcer and Behcet's syndrome", patent application number: 200910062308.8; "a traditional Chinese medicine composition for the treatment of Behcet's disease and its preparation method", Patent application number: 201210006415.0
Although it has a certain effect, it still cannot meet the actual clinical needs for the treatment of Behcet's disease, so the innovation of drugs for the treatment of Behcet's disease is imperative

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] In practice, the present invention is made from the following components by weight: 80 parts of red bean, 20 parts of Cimicifuga, 40 parts of angelica, 30 parts of turtle shell, 20 parts of Sichuan pepper, 6 parts of realgar, 30 parts of dogwood, licorice 20 parts, of which the red bean is soaked in water until the sprouts of 0.5-1cm are released, the water is filtered off, and set aside; the sprouted red beans are mixed with Cimicifuga, Angelica, Zhibeijia, Shujiao, realgar, dogwood, and licorice. Add 8-10 times the weight of water at a time, decoct twice, 1.5 hours each time, combine the decoction, filter, and concentrate the filtrate under reduced pressure to a clear paste (extract) with a relative density of 1.10-1.30 at 50°C, add the clear paste 20%-60% of the auxiliary material by weight is made into a clinically applicable traditional Chinese medicine composition preparation according to the conventional method of pharmaceutical preparations.

Embodiment 2

[0011] In practice, the present invention is made from the following components by weight: 60 parts of red bean, 10 parts of Cimicifuga, 20 parts of Angelica sinensis, 20 parts of Turtle Carapace, 10 parts of Sichuan pepper, 4 parts of realgar, 20 parts of Cornus officinalis, licorice 10 parts, of which the red bean is soaked in water until it sprouts 0.5-1cm sprouts, and the water is filtered off for later use; mix the sprouted red beans with Cimicifuga, angelica, turtle shell, Sichuan pepper, realgar, dogwood, and licorice, add Decoct in water with 10 times the weight of water for 1.5 hours, and filter out the medicinal liquid; decoct the dregs with 8 times the weight of Bawei medicine in water for 40 minutes, and filter out the medicinal liquid; combine the two decoctions, filter to obtain the filtrate, and decompress the filtrate Concentrate to a clear paste with a relative density of 1.10 at 50°C, add 20% sucrose by weight of the clear paste and 15% dextrin by weight of th...

Embodiment 3

[0013] In practice, the present invention is made from the following components by weight: 100 parts of red bean, 30 parts of Cimicifuga, 60 parts of angelica, 40 parts of turtle shell, 30 parts of Sichuan pepper, 8 parts of realgar, 40 parts of dogwood, licorice 30 parts, of which the red bean is soaked in water until the sprouts of 0.5-1cm are released, the water is filtered off, and set aside; the sprouted red beans are mixed with Cimicifuga, Angelica, Zhibeijia, Shujiao, realgar, dogwood, and licorice. Decoct in water with 10 times the weight of water for 1.5 hours, and filter out the medicinal liquid; decoct the dregs with 8 times the weight of Bawei medicine in water for 40 minutes, and filter out the medicinal liquid; combine the two decoctions, filter to obtain the filtrate, and decompress the filtrate Concentrated to 50°C, the relative density is 1.10 clear paste; add 20% starch by weight of clear paste, mix evenly, dry, pulverize, add 20% talcum powder by weight of cl...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for treating Behcet diseases, which can effectively solve the problem of a medicine for Behcet disease treatment. The technical scheme is that the traditional Chinese medicine composition is prepared from the following components in parts by weight: 60-100 parts of adzuki beans, 10-30 parts of rhizoma cimicifugae, 20-60 parts of angelica, 20-40 parts of prepared turtle shells, 10-30 parts of Sichuan peppers, 4-8 parts of realgar, 20-40 parts of dogwood and 10-30 parts of licorice roots. The traditional Chinese medicine composition is prepared through the following steps: soaking the adzuki beans into water until buds with a length of 0.5-1cm are germinated, filtering out water, and taking the adzuki beans for standby application; mixing the germinated adzuki beans, the rhizoma cimicifugae, the angelica, the prepared turtle shells, the Sichuan peppers, the realgar, the dogwood and the licorice roots, and adding water with a weight 8-10 times as large as that of the obtained mixture; decocting the obtained mixture two times, 40-90 minutes each time; merging decoctions, and filtering the merged decoctions so as to obtain filter liquor; carrying out reduced-pressure concentration on the filter liquor until a clean cream with a relative density of 1.10-1.30 at a temperature of 50 DEG C is obtained; and adding a supplementary material with a weight accounting for 20-60% of the weight of the clean cream so as to prepare a clinically applicable traditional Chinese medicine composition preparation. The traditional Chinese medicine composition disclosed by the invention is scientific in formula, easy to produce, low in cost, good in curative effect, less in toxic or side effect and obvious in advantages, and can be effectively applied to the clinical treatment of Behcet diseases, therefore, the traditional Chinese medicine composition is an innovation on traditional Chinese medicines.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for treating Behcet's disease. Background technique [0002] Behcet's disease (BD) is a chronic vascular inflammatory disease. Different from other vasculitis diseases, it can involve large, medium and small blood vessels throughout the body, and veins are the most involved. The clinical manifestations are recurrent oral ulcers, genital ulcers, ophthalmia and skin lesions, etc. It can also involve blood vessels, nervous system, digestive tract, joints, lungs, kidneys, epididymis and other organs. It is a systemic disease. It is more common in young adults aged 16-40, and women are more than men; the course of the disease is long, up to decades, and various symptoms may recur, but can be relieved by themselves; the incidence of skin lesions is very high, up to 98%. Also varied. Modern medicine is not very clear about the etiology and pathogenesi...

Claims

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Application Information

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IPC IPC(8): A61K36/758A61P9/14A61P17/02A61P1/02A61P27/02A61K35/56A61K33/36A61K35/586
Inventor 王培育高希言邵素菊张淑君任珊
Owner HENAN UNIV OF CHINESE MEDICINE
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