Absorbable medical dressing and preparation method thereof

An absorbent, water-soluble polyamide technology, applied in viscous dressings, dressings, absorbent pads, etc., can solve the problems of poor wet stability, high manufacturing cost, and difficulty in the activity of bioactive molecules, so as to improve wet stability Sexuality, improvement of healing effect, and effect of improving safety

Active Publication Date: 2013-04-10
WUHAN GREENOVO BIOTECH
View PDF4 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Traditional hemostatic dressings generally improve the hemostatic performance of the dressing by adding bioactive molecules, such as thrombin and fibrin, but the manufacturing cost of such dressings is high, and it is difficult to maintain the activity of such bioactive molecules
The existing hemostatic dressing is a chitosan derivative modified by polyacrylic acid. The porous sponge with chitosan and gelatin as the main components has poor wet stability and is easy to dissolve in wounds with a lot of blood oozing, so it cannot exert its coagulation performance

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0018] The present invention will be further described below in conjunction with embodiment.

[0019] In the present embodiment 1, at first the polymer matrix aqueous solution is prepared: choosing molecular weight is 455g of chitosan of 300 kilodal, and the degree of deacetylation of chitosan is 95%, utilizes the chitosan of choosing to prepare chitosan aqueous solution , add acetic acid and 0.4g collagen protein in the chitosan aqueous solution, the concentration of chitosan is 2.3% in the prepared chitosan aqueous solution, and the concentration of acetic acid is 4%, needs to chitosan in the chitosan aqueous solution preparation process The aqueous solution is degassed under reduced pressure, and the degassing pressure is -3×10 5 Pa, the defoaming time is 5min;

[0020] Next, the prepared polymer matrix aqueous solution is injected into the mould: the length of the mold used for the injection molding of the polymer matrix aqueous solution is 60-70 cm, and the width is 9-21...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Heightaaaaaaaaaa
Widthaaaaaaaaaa
Thicknessaaaaaaaaaa
Login to view more

Abstract

The invention provides an absorbable medical dressing. The absorbable medical dressing comprises an elastic backing and a polymeric matrix layer arranged on the backing, wherein the backing comprises at least one of polyurethane, hyaluronic acid, hyaluronate, absorbable aliphatic polyester and polyhydroxy butyric acid; the polymeric matrix layer comprises at least one of polyacrylic acid, alginic acid, chitosan, water-soluble polyamide, chitosan derivative, polylysine and cellulose derivative; a medicine layer is arranged on the polymeric matrix layer; and the medicine layer comprises at least one of collagen, fibrinogen, growth factor and antibiotic. A preparation method of the absorbable medical dressing comprises the following steps: (1) preparing a polymeric matrix aqueous solution; (2) injecting the prepared polymeric matrix aqueous solution into a mould; (3) freezing the polymeric matrix aqueous solution in the mould; (4) lyophilizing the frozen polymeric matrix aqueous solution; and (5) postprocessing polymeric matrix sponge to prepare the absorbable medical dressing.

Description

technical field [0001] The invention relates to a dressing and a preparation method thereof, in particular to an absorbable medical dressing and a preparation method thereof. Background technique [0002] Trauma is a serious problem that endangers human health. According to the World Health Organization Trauma Treatment Guidelines, 16,000 people worldwide die from trauma every day, and medical expenses due to trauma are as high as 16% of all global medical expenditures, and 1 / 2 of the trauma patients 3 is death due to blood loss and multiple organ failure related to blood loss. If the bleeding can be stopped in time and effectively, it is very important to save the life of the wounded, stabilize the injury, and create conditions for follow-up treatment. Dressing, as a hemostatic material, refers to a protective covering on the wound, which can help control bleeding, prevent infection and absorb secretions. Hemostatic dressings are of great significance for timely hemostasis...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61F13/02A61L15/28A61L15/26A61L15/44
Inventor 吴斌孙云张锐朱思洁张静颜斯
Owner WUHAN GREENOVO BIOTECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap