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Freeze-dried radix rehmanniae recens for treating anaphylactoid purpura in children

A technology for allergic purpura and fresh rehmannia, which is applied in the field of medicine, can solve the problems that the etiology and pathogenesis are not fully clarified, and there is no unified and clear treatment plan

Inactive Publication Date: 2013-04-24
JINAN KANGZHONG PHARMA TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The etiology and pathogenesis of this disease have not yet been fully elucidated, and there is no unified and clear treatment plan

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Take freeze-dried fresh rehmannia glutinosa, pulverize it to obtain a powder, pack it into 10g / bag, treat children's allergic purpura, take 2 bags per day, and take it in 2 times.

Embodiment 2

[0026] Take 10kg of buffalo horn (decocted separately), 20kg of peony bark, 20kg of white peony root, 30kg of honeysuckle, 10kg of licorice, and 60kg of rhizome of Imperata corydalis, extract twice with water, add 8 times the amount of water for the first time, extract for 1.5 hours, and add 6 times for the second time Measure water and extract for 1 hour, combine extracts, filter, concentrate, dry, add 30 kg of freeze-dried rehmannia glutinosa powder, mix well, granulate starch slurry, dry, granulate, add appropriate amount of talcum powder, compress into tablets, treat children with allergic purpura, 12 tablets per day (including 3g of freeze-dried rehmannia powder), divided into 3 times, 1 month as a course of treatment.

Embodiment 3

[0028] Take fresh rehmannia glutinosa, wash and remove impurities, and cut into 5cm-long rehmannia section; put the rehmannia section on a plate, with a loading capacity of about 4Kg / ㎡; control the freezing temperature at -28°C; when the controlled temperature is reached, immediately turn on the vacuum pump to evacuate to The pressure of the drying chamber is below 50Pa, and then start the heating switch to promote the sublimation; the temperature of the sublimation should be controlled below 40°C; the temperature of the analysis stage should be controlled below 45°C. Freeze-dried fresh rehmannia was obtained.

[0029] Take freeze-dried fresh rehmannia glutinosa and use methanol as the solvent to reflux extract, recover methanol, add water and stir evenly, extract with n-butanol, concentrate the n-butanol solution under reduced pressure, add ether to dissolve, put the insoluble matter on a mixed column of activated carbon and diatomaceous earth, and use 1-10 % ethanol solution...

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PUM

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Abstract

The invention relates to application of freeze-dried radix rehmanniae recens in preparation of drug for treating anaphylactoid purpura of children, wherein the freeze-dried radix rehmanniae recens is used for preparing the drug for treating anaphylactoid purpura of children. The drug has the freeze-dried radix rehmanniae recens or the extractive of the freeze-dried radix rehmanniae recens. The freeze-dried radix rehmanniae recens for treating anaphylactoid purpura of children has obvious curative effect on anaphylactoid purpura of children.

Description

technical field [0001] The invention relates to medicines, in particular to medicines prepared from freeze-dried fresh rehmannia root for treating allergic purpura in children, and belongs to the technical field of medicines. Background technique [0002] Rehmannia glutinosa is the fresh or dried tuber root of Rehmannia glutinosa Li-bosch. Excavated in autumn, remove reed heads, fibrous roots and silt, used fresh, commonly known as "fresh rehmannia". It is slowly baked until it is 80% dry, and it is commonly called "shengdihuang". Stew rehmannia glutinosa with wine (Appendix II D of the 2010 edition of the Chinese Pharmacopoeia) until the wine is exhausted, take it out, and dry it in the sun until the mucus on the outer skin is slightly dry; or steam it until black Moisten it, take it out, and when it is about 80% dry, cut it into thick slices or blocks, and dry it to get "Rehmannia glutinosa". The three kinds of rehmannia have different medicinal effects. Fresh rehmannia...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K36/899A61P7/04A61P37/08
Inventor 郭庆华许翠萍冯丽娟刘元水王瑛
Owner JINAN KANGZHONG PHARMA TECH DEV
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