A Simulation Method of Laser-Induced Photothermal Effect in Biological Tissue

Abstract

The invention provides a method of simulating laser-induce biological tissue photothermal effect through a resistor capacitor (RC) circuit model. The problems that required parameters are of a large number, prediction error is large, and the like exist in the method of simulation through a Pennes equation in the prior art. The simulation method includes that firstly, the RC circuit model is established; model parameters are defined; a temperature experiment is performed followingly, temperature parameters are extracted, laser power density I and a measuring position d are recorded, tissue moisture content W is measured, and a parameter e is calculated; a Tau and an A are extracted; proportionality coefficients p and s are obtained; laser and tissue types, the W, the p and the s are stored into a database; the I and the d adopted in the experiment are firstly designed when simulation is performed; the W, the p and the s are then invoked, the e is calculated according to the W and the d, the A is calculated according to the I and the p, and the Tau is calculated according to the e and the s; the A and the Tau are introduced to the model for simulation calculation; and eventually a simulation temperature response curve is compared with a practical temperature response curve to obtain a simulation error. Thus, the photothemal effect simulation can be conveniently and accurately achieved only according to the two model parameters of the Tau and the A.

Description

technical field [0001] The invention relates to a laser-induced photothermal effect simulation technology of biological tissue, in particular to a simulation method through an RC circuit model. Background technique [0002] Laser surgery is an emerging technology, which is more and more widely used in medicine. It can effectively remove diseased tissues, with clear cutting vision, less bleeding, and faster wound healing. However, due to the laser energy used for cutting Higher, short action time, and there is a great risk of human control: if the laser power, action distance and action time are not controlled accurately, it is easy to cause damage to the surrounding normal tissues. In clinical practice, laser energy is often lowered to achieve time control. , but the operation time is prolonged, the hemostatic effect is not good, and there is potential damage. On the other hand, the tissue temperature rises rapidly during laser surgery, the temperature is very high, and it i...

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Problems solved by technology

[0006] The purpose of the present invention is to solve the problems of too many parameters and low temperature prediction accuracy in the existing research on laser-induced photothermal effect of biological tissue, and to provide a simulation method of laser-induced photothermal effect of biological tissue, which can be conveniently and accurately Simulating the temperature rise of biological tissue under laser irradiation

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