Natural drug extract and its preparation method

A technology of natural medicines and extracts, used in drug combinations, pharmaceutical formulations, antitumor drugs, etc.

Inactive Publication Date: 2013-10-23
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural drug extract and its preparation method

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Embodiment approach

[0031] The first step: preparation of various extracts

[0032] (1) Preparation of concentrated extract of astragalus and cardamom decoction

[0033] Take astragalus and cardamom according to the compatibility ratio of 1-6:1, soak in distilled water, heat and decoct, filter, add distilled water to the dregs, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate, and ultrafilter Membrane filtration, drying under reduced pressure, that is.

[0034] (2) Preparation of astragalus polysaccharide

[0035] Astragalus is crushed, extracted saponin with 95% ethanol, dried, added distilled water, and saturated lime water drop by drop, adjusted the pH value, left to stand for 10 minutes to moisten the material, irradiated with microwave for 1 minute, irradiated for 1 minute after an interval of 1 minute, and filtered to obtain the extract , repeat the above operation 2-3 times, combine the extracts, concentrate, adjust the pH=7 with 10% hydrochloric acid...

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Abstract

The invention relates to a natural drug extract and its preparation method. The natural drug extract is composed of an astragalus Alpinia katsumadai decocted concentrated extract, astragalus polysaccharides and an Alpinia katsumadai ethyl acetate extract in a ratio of 2-8:3-9:2-3. The composition provided in the invention has excellent efficacy on cancer chemotherapy related diarrhea and simultaneously has a synergistic effect on cancer chemotherapy.

Description

technical field [0001] The present invention relates to a kind of natural medicine extract, more specifically relate to a kind of natural medicine extract that is composed of astragalus, grass cardamom water decoction concentrated extract, astragalus polysaccharide and grass cardamom ethyl acetate extract, the preparation of the natural medicine extract The method and the use of the natural medicine extract in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs used alone or in combination can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chem...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P35/00A61P1/12A61K31/715
Inventor 石强
Owner 石强
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