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Product for treating systemic lupus erythematosus and rheumatism and preparation method thereof

A systemic technology for lupus erythematosus, which can be applied to medical preparations containing active ingredients, allergic diseases, pharmaceutical formulations, etc. and developmental effects

Active Publication Date: 2013-11-20
SANCAI SHIQI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These drugs have some effect on the treatment of single symptom of lupus erythematosus, but have no obvious effect on lupus erythematosus manifested as rheumatism

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 11

[0063] The preparation of the No. 1.1 product of embodiment

[0064] Step 1. Chinese medicinal water extract preparation

[0065] Chinese medicine raw materials and their parts by weight: 20 parts of Clematis, 30 parts of Chuanxiong, 40 parts of Rubia, 40 parts of evening silkworm excrement, 30 parts of red bean, 40 parts of angelica, 20 parts of cinnamon, and 30 parts of chive seeds.

[0066] (1) Take a total of 28kg according to the above raw drug components;

[0067] (2) Add water 5-6 times the total amount of raw materials of traditional Chinese medicine, boil on high heat, decoct on low heat, 0.5 hours each time, filter to get juice;

[0068] (3) Repeat (2) 5 times, and collect all the filtrates to obtain a total weight of about 150kg of Chinese medicinal water extract.

[0069] Step 2. Prepare morel mycelium stock solution

[0070] Material: Mother species of Morehellaspp esculenta (L.) Pers, Agricultural Culture Collection of China (Agricultural Culture Collection of...

Embodiment 22

[0104] Example 2.2 product

[0105] Step 1. Chinese medicinal water extract preparation

[0106] Chinese medicine raw materials and parts by weight thereof: Chinese medicine raw materials of said weight components: 40 parts of Clematis, 20 parts of Chuanxiong, 20 parts of madder, 30 parts of evening silkworm excrement, 20 parts of red bean, 30 parts of angelica, 40 parts of cinnamon, leek Sub 20 servings.

[0107] (1) Take a total of 20kg according to the above raw material components;

[0108] (2) Add water 5-6 times the total amount of raw materials of traditional Chinese medicine, boil on high heat, decoct on low heat, 0.5 hours each time, filter to get juice;

[0109] (3) Repeat (2) 5 times, and collect all the filtrates to obtain a total weight of about 150kg of Chinese medicinal water extract.

[0110] Other steps are with embodiment 1.

[0111] The only difference is that the volume ratio of the hickory chick mycelium stock solution to the Chinese medicinal water ex...

Embodiment 33

[0112] Preparation of No. 3.3 product of embodiment

[0113] Step 1. Chinese medicinal water extract preparation

[0114] Traditional Chinese medicine raw materials and their parts by weight: 30 parts of Lingxian, 40 parts of Chuanxiong, 30 parts of madder, 20 parts of evening silkworm excrement, 40 parts of red bean, 20 parts of angelica, 30 parts of cinnamon, and 40 parts of chive seeds.

[0115] (1) A total of 35kg is weighed according to the above-mentioned raw material components;

[0116] (2) Add water 5-6 times the total amount of raw materials of traditional Chinese medicine, boil on high heat, decoct on low heat, 0.5 hours each time, filter to get juice;

[0117] (3) Repeat (2) 5 times, and collect all the filtrates to obtain a total weight of about 150kg of Chinese medicinal water extract.

[0118] Step 2. Carry out submerged fermentation with the hickory chick test tube parent species of Accc51837 with the preservation number purchased

[0119] The Chinese medici...

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Abstract

The invention provides a product for treating systemic lupus erythematosus and rheumatism and a preparation method thereof, and belongs to the field of Chinese patent medicine and pharmacy technology thereof. The invention is characterized in that the product is obtained from common submerged fermentation of a water extract of the following traditional Chinese medicines and a morel mother strain: 20-40 parts of radix clematis, 20-40 parts of Ligusticum wallichii, 20-40 parts of madder, 20-40 parts of late silkworm excrement, 20-40 parts of red adzuki beans, 20-40 parts of angelica, 20-40 parts of cinnamon and 20-40 parts of semen allii tuberosi. In some embodiments, a fetus cervi powder is added in the submerged fermentation, so that the product is rich in plant polypeptides from traditional Chinese medicines. Fungus polysaccharide of the morel, animal polysaccharide from the fetus cervi powder and coordination compounds of the three polysaccharides have substantial effects on integrally enhancing immunity of the patients. The product provided by the invention can simultaneously treat principal and subordinate symptoms, and have no toxic or side effect, and fast effectiveness.

Description

technical field [0001] The invention relates to a traditional Chinese medicine formula and pharmaceutical technology, in particular to a product for treating systemic lupus erythematosus and rheumatism and a preparation method thereof. Background technique [0002] Systemic lupus erythematosus, systemic lupus erythematosus; SLE, is a diffuse, systemic autoimmune disease, mainly involving the skin and mucous membranes, skeletal muscles, kidneys and the central nervous system, and can also involve the lungs, heart, blood and other organs and System, showing a variety of clinical manifestations; a variety of autoantibodies and immunological abnormalities can be detected in the serum. [0003] pathogenesis [0004] (1) Disease susceptibility: [0005] SLE is not a genetic disease of a single gene, but its pathogenesis is related to a variety of genetic abnormalities. It is a polygenic disease, such as HLA-DR2 and HLA-DR3 molecules and their subtypes are significantly related t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61P37/02A61P29/00A61K35/64
Inventor 彭都
Owner SANCAI SHIQI PHARMA CO LTD
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