Food composition for intra-operative tube feeding

A composition, a technology of a nutritional composition, applied in the field of alleviating, weakening or preventing acute inflammatory reactions during or after surgery, capable of solving problems not raised

Active Publication Date: 2014-02-19
NUTRICIA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Therefore, until now, it has not been suggested that during surgery, that is, during surgery, routinely feeding patients to alleviate, reduc

Method used

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  • Food composition for intra-operative tube feeding
  • Food composition for intra-operative tube feeding
  • Food composition for intra-operative tube feeding

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Embodiment Construction

[0026] The present invention relates to a liquid nutritional composition containing a substantial amount of fat and a substantial amount of proteinaceous material, and to its use for alleviating, attenuating or preventing acute inflammatory reactions in patients undergoing surgery during or after said surgery, wherein said combination Drugs were administered to the patient by intraoperative gavage. This setting requires an immediate effect of the feeding, where the effect of the feeding is to attenuate the inflammatory response. By immediate response is meant that the attenuation begins within 30 minutes, preferably within 15 minutes, and lasts several hours, especially 1-3 hours, after the intervention has stopped.

[0027] According to one embodiment, the present invention relates to a liquid nutritional composition comprising fat and protein substances for alleviating, attenuating or preventing acute inflammatory reactions in patients undergoing surgery during or after said...

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Abstract

The present invention pertains to a liquid nutritional composition comprising fat and proteinaceous matter, wherein said fat contributes for at least 41 En% and said proteinaceous matter contributes for at least 23 En% to the total energy content of said composition, for mitigating, attenuating or preventing an acute inflammatory response during or after surgery of a patient undergoing said surgery, wherein said composition is to be administered to said patient by intra-operative tube feeding,as well as to specific liquid nutritional compositions, suitable for use as a tube feed,and especially for mitigating, attenuating or preventing an acute inflammatory response during or after surgery of a patient.

Description

technical field [0001] The present invention relates to a liquid nutritional composition and its use for intraoperative administration by gavage of a lipid-rich and protein-rich liquid nutritional composition for alleviating, attenuating or preventing acute inflammatory reactions during or after surgical operations . Background technique [0002] The mammalian body can mount an inflammatory response in response to a stressor. Stressors can be infectious or non-infectious sources. Examples of stressors are microorganisms (viruses, bacteria, fungi, or parasites) or nonendogenous protein or peptide-related substances that have locally invaded tissue, physical trauma (including surgery), severe blood loss, extracorporeal circulation, or extensive soft tissue Injuries and multiple fractures, ischemia / reperfusion events, or cell or tissue damage caused by burns, chemotherapy, radiation, or poisoning. In an inflammatory response, many factors play a role. Inflammatory mediators...

Claims

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Application Information

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IPC IPC(8): A23L1/30A23L1/305A61K45/06
CPCA23L1/3053A23L1/3051A23L1/296A23L1/3006A23L1/3055A23L1/3056A61K45/06A23L33/40A23V2002/00A23V2200/30A23V2250/54246A23V2250/54252A23V2250/5488A23V2250/5486A23V2250/548A23L33/115A23L33/175A23L33/18A23L33/185A23L33/19A61P3/02A61P41/00
Inventor Z·霍夫曼M·克莱巴克T·鲁贝尔斯J·J·德哈恩W·A·布尔曼J·W·M·格雷夫A·J·M·弗里瑟玛
Owner NUTRICIA
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