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Pharmaceutical composition for treating rhinitis and its preparation method and application

The technology of a composition and medicine is applied to the pharmaceutical composition for treating rhinitis and the fields of preparation and use thereof, which can solve the problems of inability to completely treat, toxic and side effects, and achieve the effect of high total effective rate of treatment.

Active Publication Date: 2016-08-17
CHENGDU COMFAITH PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these drugs have certain toxic and side effects on the human body, and they still cannot be completely cured

Method used

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  • Pharmaceutical composition for treating rhinitis and its preparation method and application
  • Pharmaceutical composition for treating rhinitis and its preparation method and application
  • Pharmaceutical composition for treating rhinitis and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation method of embodiment 1 composition of the present invention

[0025] prescription:

[0026] Huoxiang 15g, Scrophulariaceae 20g, Magnolia 9g, Rubia 10g, Fritillaria 12g, Bupleurum 9g, Angelica 10g, Uncaria 15g, Mint 15g, Loofah 15g, Honeysuckle 15g, Licorice 8g, Angelica 10g, Earthworm 10g, pomegranate peel 10g, myrobalan 10g, cicada slough 6g, astragalus 10g, Nepeta charcoal 10g, black plum 10g, Xu Changqing 10g, cinnamon twig 3g, white peony 12g, dew hive 6g, comfrey 10g, wild chrysanthemum 10g, oyster 20g, Schisandra 12g, Duckweed 15g, Eclipta 10g, Luo Han Guo 20g, Campanulaceae 10g.

[0027] Preparation:

[0028] Take the above-mentioned crude drug, add water to decoct 3 times, combine the decoction, and filter to obtain the decoction.

Embodiment 2

[0029] The preparation method of embodiment 2 compositions of the present invention

[0030] prescription:

[0031] Huoxiang 12g, Scrophulariaceae 25g, Xinyi flower 12g, Rubia 13g, Fritillaria 15g, Bupleurum 12g, Angelica 13g, Uncaria 18g, Mint 18g, Loofah 18g, Honeysuckle 18g, Licorice 11g, Angelica 13g, Earthworm 13g, pomegranate peel 13g, myrobalan 13g, cicada slough 8g, astragalus 13g, Nepeta charcoal 13g, black plum 13g, Xu Changqing 13g, cinnamon twig 5g, white peony 15g, dew hive 8g, comfrey 13g, wild chrysanthemum 13g, oyster 25g, Schisandra 15g, Duckweed 18g, Eclipta 13g, Luo Han Guo 25g, Bellflower 13g.

[0032] Preparation:

[0033] Take the above crude drug, extract it with 50-55% v / v ethanol for 3 times, combine the ethanol extracts, filter, recover ethanol, concentrate, add appropriate amount of dextrin, and granulate to obtain granules.

Embodiment 3

[0034] The preparation method of embodiment 3 compositions of the present invention

[0035] prescription:

[0036] Huoxiang 18g, Scrophulariaceae 15g, Magnolia 6g, Rubia 7g, Fritillaria 9g, Bupleurum 6g, Angelica 7g, Uncaria 12g, Mint 12g, Loofah 12g, Honeysuckle 12g, Licorice 5g, Angelica 7g, Earthworm 7g, pomegranate peel 7g, myrobalan 7g, cicada slough 4g, astragalus 7g, Nepeta charcoal 7g, black plum 7g, Xu Changqing 7g, cinnamon twig 2g, white peony 9g, dew hive 4g, comfrey 7g, wild chrysanthemum 7g, oyster 15g, Schisandra 9g, Duckweed 12g, Eclipta 7g, Luo Han Guo 15g, Bellflower 7g.

[0037] Preparation:

[0038] Take the above raw materials, extract twice with 80-85% v / v ethanol, and combine the alcohol extract; decoct the dregs with water twice, combine the water decoction; take the alcohol extract, recover ethanol, and combine with the water decoction , concentrate, add an appropriate amount of starch, mix well, dry, granulate, and pack into capsules to obtain cap...

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Abstract

The invention provides a pharmaceutical composition for treating rhinitis, which is a preparation prepared from the following raw medicines in parts by weight: 12-18 parts of agastache rugosus, 15-25 parts of radix scrophulariae, 6-12 parts of magnolia flower, 7-13 parts of radix rubiae, 9-15 parts of thunberg fritillary bulb, 6-12 parts of radix bupleuri, 7-13 parts of angelica sinensis, 12-18 parts of uncaria rhynchophylla, 12-18 parts of mint, 12-18 parts of loofah sponge, 12-18 parts of honeysuckle stem, 5-11 parts of liquorice, 7-13 parts of radix angelicae, 7-13 parts of lumbricus, 7-13 parts of pericarpium granati, 7-13 parts of fructus chebulae, 4-8 parts of periostracum cicada, 7-13 parts of astragalus membranaceus, 7-13 parts of black tenuifolia, 7-13 parts of dark plum, 7-13 parts of cynanchum paniculatum, 2-5 parts of cassia twig, 9-15 parts of radix paeoniae alba, 4-8 parts of nidus vespae, 7-13 parts of radix arnebiae seu lithospermi, 7-13 parts of wild chrysanthemum flower, 15-25 parts of concha ostreae, 9-15 parts of schisandra chinensis, 12-18 parts of lesser duckweed, 7-13 parts of eclipta alba, 15-25 parts of momordica grosvenori and 7-13 parts of platycodon grandiflorum. The pharmaceutical composition disclosed by the invention can be used for effectively treating chronic allergic rhinitis, has the effects of eliminating or relieving symptoms such as rhinobyon, rhinocnesmus, much nasal mucus, clear nasal mucus, olfaction decline, headache or dizziness and the like caused by the rhinitis, also has a high total effective rate in treatment and provides a new choice for clinical medication.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating rhinitis, a preparation method and application thereof. Background technique [0002] Rhinitis is an inflammatory disease of the nasal cavity, which is the inflammation of the nasal mucosa caused by viruses, bacteria, allergens, various physical and chemical factors, and certain systemic diseases. Chronic allergic rhinitis, also known as allergic rhinitis, refers to the release of mediators (mainly histamine) mediated by IgE after exposure to allergens in atopic individuals, and a variety of immune active cells and cytokines are involved. Noninfectious inflammatory disease of the mucosa. There are three necessary conditions for its occurrence: ① Specific antigen is the substance that causes the body's immune response. ② Atopic individuals are the so-called individual differences and allergies. ③ The specific antigen meets the atopic individual. Allergic rhinitis is a global health p...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8966A61P11/02A61P37/08A61P29/00A61P25/00A61K35/618A61K35/62A61K35/64A61K35/644
Inventor 夏隆江何宇新刘蓓李昌龙张翠媚
Owner CHENGDU COMFAITH PHARMA
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