Medicine for promoting rise of hemameba number after radiotherapy and chemotherapy and preparation method thereof

A technology of white blood cells, radiotherapy and chemotherapy, applied in the field of pharmacy, can solve the problems of increased toxicity and side effects, affecting the treatment effect, and greater physical damage to patients, and achieves rapid onset and good curative effect

Inactive Publication Date: 2014-06-25
QINGDAO TUMOR HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, most of the treatment methods for tumors are combined with radiotherapy and chemotherapy, especially for some patients who have no chance of surgery, in addition to taking drugs, radiotherapy and chemotherapy are mainly used. It will cause leukopenia, which will cause great damage to the patient's body. For this reason, injections to increase leukocytes are also used, or western medicines such as batyl alcohol, leucogen, leucopeptide, and colony cell stimulating factor are taken. However, the above methods can only improve Many diseases of patients cannot be improved, which greatly affects the treatment effect, and reduces the patient's immune function and quality of life

Method used

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preparation example Construction

[0064] When the dosage form of medicine is capsule, described preparation method comprises the following steps:

[0065]a. Mix white peony root, donkey-hide gelatin, grass fruit, sealwort, Nansha ginseng, lily and Ophiopogon japonicus, add 5-10 times the amount of water to soak for 1-2 hours, extract the volatile oil for 2-5 hours, collect the volatile oil, and filter the liquid The medicinal residues are used for subsequent use; the extraction of the volatile oil adopts steam distillation or supercritical extraction;

[0066] b. Take the remaining raw medicinal materials and mix them with the dregs of the step a, add 60%-90% ethanol, soak for 0.5-1.5 hours, extract twice, each time for 1-2 hours, add 5-10 times the amount for the first time , add 5-10 times the amount for the second time, combine the extracts, and filter; concentrate the filtrate under reduced pressure to a relative density of 1.10-1.50 at 80°C, precipitate with alcohol twice, adjust the ethanol concentration...

Embodiment 1

[0073] Example 1 Capsules

[0074] The embodiment of the present invention provides a medicine for promoting the number of white blood cells after radiotherapy and chemotherapy, wherein the parts by weight of each raw medicinal material are: 25 parts by weight of Radix Paeoniae Alba, 23 parts by weight of donkey-hide gelatin, 15 parts by weight of Cao Guo, and 15 parts by weight of Polygonatum 15 parts by weight of Nansha Ginseng, 21 parts by weight of Lily, 22 parts by weight of Ophiopogon japonicus, 21 parts by weight of Asparagus, 15 parts by weight of Dendrobium, 14 parts by weight of Polygonatum odoratum, 21 parts by weight of Ming Codonopsis, 25 parts by weight of Lycium barbarum, Mohan 20 parts by weight of lotus, 21 parts by weight of lychee core, 24 parts by weight of mulberry, 16 parts by weight of tortoise shell, 18 parts by weight of coix seed, 19 parts by weight of chicken vine, 23 parts by weight of Geshanxiao, 20 parts by weight of shouwu vine, 22 parts by weight...

Embodiment 2

[0080] Example 2 tablet

[0081] The embodiment of the present invention provides a drug for promoting the number of white blood cells after radiotherapy and chemotherapy, wherein the parts by weight of each raw medicinal material are: 23 parts by weight of Radix Paeoniae Alba, 25 parts by weight of donkey-hide gelatin, 17 parts by weight of Tsao Guo, and 13 parts by weight of Polygonatum 15 parts by weight of Nansha Ginseng, 21 parts by weight of Lily, 22 parts by weight of Ophiopogon japonicus, 18 parts by weight of Asparagus, 15 parts by weight of Dendrobium, 15 parts by weight of Polygonatum odoratum, 21 parts by weight of Ming Codonopsis, 23 parts by weight of Lycium barbarum, Mohan 20 parts by weight of lotus, 20 parts by weight of lychee core, 23 parts by weight of mulberry, 15 parts by weight of tortoise shell, 15 parts by weight of coix seed, 20 parts by weight of chicken vine, 23 parts by weight of Geshanxiao, 20 parts by weight of shouwu vine, 22 parts by moray eel e...

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PUM

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Abstract

The invention discloses a medicine for promoting rise of hemameba number after radiotherapy and chemotherapy and a preparation method thereof. The medicine includes the following raw medicinal materials: radix paeoniae alba, donkey-hide gelatin, amomum tsao-ko, rhizoma polygonati, adenophora tetraphylla, lily, ophiopogon japonicus, asparagus, dendrobium, radix polygonati officinalis, changium smyrnioides, fructus lycii, eclipta, semen litchi, mulberry, tortoise shell, semen coicis, fevervine, Cynanchum wilfordii, vine of multiflower knotweed, eel eggs, coriander seed, lucid ganoderma and cardamun. The medicine disclosed by the invention has the beneficial effects that the medicine mainly has the functions of reinforcing qi and nourishing blood, nourishing liver and kidney, replenishing essence and generating marrow, and when being used for treating leucopenia caused by radiotherapy and chemotherapy, the medicine has the advantages of allowing to fast effect and being good in curative effect, high in safety and capable of improving the living quality of patients.

Description

[0001] technical field [0002] The invention relates to the technical field of pharmacy, in particular to a medicine for increasing the number of white blood cells after radiotherapy and chemotherapy and a preparation method thereof. [0003] Background technique [0004] Leukopenia is a group of syndromes caused by various reasons, and the total number of peripheral blood leukocytes is continuously lower than 4.0×10 9 / L is the main diagnostic basis, and it is relatively common in clinical medicine at present. According to its etiology, it can be divided into two types: unknown cause and secondary, and leukopenia secondary to tumor radiotherapy and chemotherapy is particularly common. Chemoradiotherapy is chemical birth therapy, which is a drug-based treatment for diseases caused by pathogenic microorganisms, parasites, and malignant tumors. Chemotherapy is also the initiation of cancer treatment with drugs that kill tumor cells, sometimes called cytotoxic drugs. Radiat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P7/00A61K35/60A61K35/56A61K35/36A61K35/38A61K35/57A61K35/586
Inventor 刘洁张淑玲张佩娟蔡淑珍
Owner QINGDAO TUMOR HOSPITAL
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