Osteochondral three-dimensional stent with regular interpenetrating network structure and preparation method thereof

A technology of interpenetrating network structure and three-dimensional scaffold is applied in the field of osteochondral three-dimensional scaffold and its preparation, which can solve the problem that the mechanical strength of the scaffold is not taken into account, and achieve the effect of a large control range.
CN103893818BInactive Publication Date: 2015-07-01SOUTH CHINA UNIV OF TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SOUTH CHINA UNIV OF TECH
Publication Date
2015-07-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses an osteochondral three-dimensional stent with a regular interpenetrating network structure. A biological medical high polymer material system and an in-situ generated hydrogel material system form the regular interpenetrating network structure. The osteochondral three-dimensional stent is provided with a multi-layer structure which is divided into a calcified layer, a radiation layer, a transition layer and a superficial layer. The invention further discloses a preparation method of the osteochondral three-dimensional stent. By virtue of a 3D (Three-dimensional) printing technology, the biological medical high polymer material system and the in-situ generated hydrogel material system inside the stent form the interpenetrating network structure. As a novel integral joint osteochondral three-dimensional stent, the osteochondral three-dimensional stent disclosed by the invention is combined with mechanical performance and functional requirements of the stent, can effectively promote repair of each area of the cartilage and can finally achieve an integral repair purpose of the cartilage.
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Description

technical field

[0001] The invention relates to a three-dimensional osteochondral scaffold and a preparation method thereof, in particular to a three-dimensional osteochondral scaffold with a regular interpenetrating network structure and a preparation method thereof. Background technique

[0002] In the 1990s, American scholars Vacant and Langer proposed the concept of regenerative medicine of tissue engineering, and now a new discipline of tissue engineering has gradually formed. Tissue engineering is the use of the principles and methods of life science and engineering to research and develop a new generation of clinically applied substitutes that can repair or improve the functions of human tissues or organs, and are used to replace part or all of the functions of tissues or organs. The development of tissue engineering also provides another way for the repair of cartilage damage, especially in solving the problem of the source of transplanted tissue, combining cytokines...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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