7 results about "Transplanted tissue" patented technology

The utility model relates to a kind of adipose tissue preparation devices, belong to adipose tissue preparation technical field, including outer tube, outer tube upper end sealing connection upper end cover, outer tube lower end sealing connection lower end cover, upper end cover, lower end cover and outer tube are jointly surrounded to form cavity;Outer tube center is set through center shaft assembly;Turbine blade is rotationally set on center shaft assembly, and turbine blade is located in cavity;The utility model only processes adipose tissue by mechanical shearing, avoids the damage of chemical substance to adipose tissue biological activity, guarantees the biological safety of transplant tissue;Rely on manually pushing and pulling center shaft assembly, drive turbine blade to rotate under the resistance of component in cavity, without power or other power source, simple structure, small and exquisite, convenient to carry and operate;Shear stress generated by turbine blade rotation is even controllable, can stably and quickly break adipose tissue, and the broken efficiency is high, and particle size uniformity is good, meet the requirement of clinical transplantation injection.

The invention discloses an oral threaded retention nail and a method for fixing a gingival flap in a free gingival transplantation operation. The retention nail comprises a head part, the head part is connected with a polished rod, one end of the polished rod is provided with a threaded part, and the threaded part is connected with a tail part; a drug delivery mechanism is arranged in the polish rod, a plurality of slow-release micropores are formed in the threaded part and the tail part, and the slow-release micropores are connected with the drug delivery mechanism; the medicine feeding mechanism is connected with a pressing assembly, and the pressing assembly is located at the head. The method comprises the following steps: anesthetizing a recipient area and a donor area, preparing the recipient area, obtaining transplanted tissues, transplanting the transplanted tissues to the wound surface of the recipient area, and treating the wound surface of the donor area. According to the method, the gingival flap can be continuously and tightly attached to the planted bed, the tissue flap rejection risk is remarkably reduced, and the transplanting survival rate is increased; meanwhile, through the arrangement of the pressing assembly and the dosing mechanism, regular and long-term dosing is facilitated.

The present invention provides method for monitoring physiological status of an organ in a subject by monitoring morphological changes over time in transplanted tissue on an eye of the subject.

The invention provides a rootless and leafless ginger tissue culture seedling cultivation method, and relates to the field of seed and seedling cultivation, and the method comprises the following steps: material preparation, mixed matrix preparation, and tissue culture seedling field planting: the rootless and leafless tissue culture seedling is vertically implanted into a mixed matrix implantation hole, the root neck part is ensured to be completely embedded into the matrix hole, the stem section is upright, and the root and the leaf are completely embedded into the matrix hole; the matrix around the seedlings is slightly compacted, so that the seedlings are fixed without lodging; and finally, sequentially carrying out four-stage cultivation according to time to obtain the transplanted tissue culture seedlings. According to the method, by transplanting rootless and leafless tissue culture seedlings and rebuilding root systems, ginger plant groups with consistent tillering and balanced structure are cultivated, so that the adaptability and the survival rate after transplanting are improved.

The invention relates to a method for preservation of a tissue or an organ previously obtained from a mammal, for transplant of said tissue or organ in a recipient compatible mammal, the method comprising: - contacting, preferably in vitro or ex vivo, said tissue or organ with a treating composition, the treating composition comprising a neddylation pathway inhibitor, for 1 to 12h hours, in order to obtain a treated tissue or organ, said composition comprising from 1 to 100 µM of said neddylation pathway inhibitor; - washing the treated tissue or organ with a conservation composition for removing the treating composition from the treated tissue or organ, in order to obtain a washed tissue or organ; and - contacting washed tissue or organ with a preservation composition, in order to obtain a ready to be transplanted tissue or organ.

This invention discloses an integrated artificial cornea and its preparation method, belonging to the field of biomedical engineering technology. The artificial cornea comprises a main corneal layer and a posterior corneal layer. The main corneal layer includes a central optical zone, a transitional junction zone, and a decellularized corneal annular zone. The main corneal layer uses a decellularized cornea as its overall framework. Polymerizable monomers are introduced into the decellularized corneal stroma and then cured using in-situ gradient curing technology. The integrated artificial cornea provided by this invention uses a decellularized cornea as its overall framework, eliminating the need for central perforation, resulting in better morphological stability. The optical zone constructed using gradient curing technology provides a favorable environment for cell ingrowth, promoting healing between the transplanted tissue and the corneal graft material.

Disclosed are miniaturized, wearable microneedle biosensor devices, systems, and methods for measuring intradermal concentrations of various metabolites (including but not limited to lactate, pyruvate, and / or glucose) in order to directly assess the viability of living tissue (e.g., human or other mammalian soft tissue). In a variety of implementations, for example, the disclosed microneedle biosensor devices are self-contained in terms of power source, sample acquisition, measurement, and data transmission capabilities, e.g., allowing it to function autonomously once placed. In some implementations, for example, the disclosed microneedle biosensor devices can assess the viability of soft tissue (e.g., skin with or without fat, fascia, or muscle) during and after reconstructive surgery in which soft tissue is repositioned, rotated, or transferred to another site in the body (including but not limited to both microvascular free tissue transfer and regional pedicled flaps).