Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Detection method of traditional Chinese medicine composition preparation having effects of moving qi and invigorating blood circulation

A technology of promoting qi and blood circulation and composition, which is applied in the field of traditional Chinese medicine and can solve the problems that western medicine cannot cure the root cause

Active Publication Date: 2014-08-06
启迪药业集团股份公司
View PDF1 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There are many types of drugs currently used in the treatment of coronary heart disease, most of which cannot cure the root cause

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Detection method of traditional Chinese medicine composition preparation having effects of moving qi and invigorating blood circulation
  • Detection method of traditional Chinese medicine composition preparation having effects of moving qi and invigorating blood circulation
  • Detection method of traditional Chinese medicine composition preparation having effects of moving qi and invigorating blood circulation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0278] Embodiment 1 oral liquid

[0279] Prescription raw material composition: Jujube 200g, Salvia miltiorrhiza 300g, Mulberry 200g, Safflower 50g, Hawthorn 200g;

[0280] Take the prescribed amount of raw material, add water and decoct twice, the first time is 2 hours, the second time is 1.5 hours, the decoction is combined, filtered, the filtrate is concentrated to a relative density of 1.10-1.12 (50°C), and ethanol is added to contain Alcohol content to 50%, stand still, filter, the filtrate recovers ethanol until there is no alcohol smell, and concentrates to a relative density of 1.15-1.20 (60°C), adds honey 200g, potassium sorbate 2.5g, filters, and adjusts the pH to 3.5-5.5, made into about 1000ml, filled and sterilized to obtain oral liquid.

[0281] Specifications: 10ml per bottle.

[0282] Usage and dosage: take orally, 10ml each time, 3 times a day.

Embodiment 2

[0283] Example 2 tablet

[0284] Prescription raw material composition: Jujube 180g, Salvia miltiorrhiza 350g, Mulberry 180g, Safflower 55g, Hawthorn 180g;

[0285] Take the prescribed amount of raw material, add 5 times the amount of 60% ethanol to reflux and extract twice, each time for 1.5 hours; combine the extracts, filter, recover the ethanol and concentrate to a relative density of 1.15-1.20 (60°C); dry under reduced pressure , crushed into fine powder, added conventional auxiliary materials, mixed; dry pressed granules, tableted, that is.

Embodiment 3

[0286] Embodiment 3 capsules

[0287] Prescription raw material composition: jujube 300g, salvia miltiorrhiza 250g, mulberry 300g, safflower 40g, hawthorn 300g; take the prescribed amount of raw material drug, add 10 times the amount of methanol ultrasonic extraction 3 times, the first 40min, the second and third times respectively For 20 minutes, combine the extracts, filter, and concentrate under reduced pressure to a thick paste with a relative density of 1.15-1.20 (60°C); take the thick paste and dry it under reduced pressure, grind it into fine powder, add conventional excipients, and mix well; dry-press granules, Pack into capsules and get ready.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
wavelengthaaaaaaaaaa
Login to View More

Abstract

The invention provides a traditional Chinese medicine composition having effects of moving qi and invigorating blood circulation, a preparation method of the traditional Chinese medicine composition and a detection method of a preparation of the traditional Chinese medicine composition. The detection method comprises the following steps of 1, constructing chromatogram conditions comprising a methanol-acid aqueous solution as a mobile phase, isocratic elution and detection wavelength of 250-350nm, 2, preparing a tested object solution by taking a traditional Chinese medicine composition preparation and adding methanol into the traditional Chinese medicine composition preparation to obtain the tested object solution, 3, preparing a contrast object solution by taking a salvianic acid A sodium contrast object and adding methanol into the salvianic acid A sodium contrast object to obtain the contrast object solution, and 4, carrying out determination by respectively taking the contrast object solution and the tested object solution by suction, pouring the solutions into a high performance liquid chromatograph and carrying out high performance liquid chromatography determination. Raw material medicines of the traditional Chinese medicine composition comprises, by weight, 60-500 parts of fructus choerospondiatis, 110-700 parts of red sage root, 50-500 parts of mulberry, 10-100 parts of safflower and 50-500 parts of haw. The traditional Chinese medicine composition has stable clinical curative effects on thoracic obstruction (coronary heart disease-caused angina) and qi stagnation and blood stasis. The invention also provides a traditional Chinese medicine composition content determination method, and the method has good specificity, high precision, good stability and good repeatability.

Description

technical field [0001] The invention relates to a detection method of a traditional Chinese medicine composition preparation, in particular to a detection method of a traditional Chinese medicine composition preparation with the function of promoting qi and blood circulation, and belongs to the field of traditional Chinese medicine. Background technique [0002] The full name of coronary heart disease is coronary atherosclerotic heart disease, which is called "chest pain" in traditional Chinese medicine. It is a common and frequently occurring disease of the cardiovascular system. Has become today's invisible killer. Coronary heart disease is mainly caused by various degrees of myocardial hypoxia and ischemia caused by coronary atherosclerosis. Traditional Chinese medicine believes that the pathogenesis of coronary heart disease lies in the blockage of the heart vessels, which is mostly caused by blood stasis, turbid phlegm, and stagnation of Qi, and is the result of long-t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61P9/10A61P3/06G01N30/90
Inventor 谭帮青雷萍彭栋梁张剑阳佑华
Owner 启迪药业集团股份公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com