Foot-bathing medicinal vinegar for quickly treating dermatophytosis and preparation method thereof

A technology of medicated vinegar and bath medicine, which is applied in the field of medicine, can solve the problems of affecting the efficacy of the product, not being able to obtain enough antibacterial ingredients, and low solubility, and achieve the effect of improving microcirculation and anti-ulcer, solving the problem of drug stability, and fast onset of action

Active Publication Date: 2014-09-03
湖南天龙制药有限公司
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AI-Extracted Technical Summary

Problems solved by technology

Most alkaloids in medicinal materials exist in the form of organic acid salts and free bases, and generally have low solubi...
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Abstract

The invention relates to the technical field of medicines, and discloses bathing medicinal vinegar for quickly treating dermatophytosis and a preparation method thereof. The foot-bathing medicinal vinegar comprises a medicinal vinegar liquid and antibacterial powder, wherein the medicinal vinegar liquid is prepared from cortex phellodendri, radix sophorae flavescentis, cortex pseudolaricis, pepper, 95% ethanol, acetic acid, mint, benzoic acid, glycerinum, 75% ethanol and water; and the antibacterial powder is prepared from alum, boronic acid, rhizoma smilacis glabrae, edible salt and talc powder.According to the foot-bathing medicinal vinegar, the traditional Chinese medicinal formula is optimized, a mode of combining traditional Chinese medicine and western medicine is adopted, and the foot-bathing medicinal vinegar is divided into a medicinal vinegar liquid part and an antibacterial powder part, so that the problem of drug stability can be solved, and the effects of quick response, high cure rate, no relapse and no irritation on skin can be achieved.

Application Domain

AntimycoticsDermatological disorder +4

Technology Topic

IrritationBoronic acid +10

Image

  • Foot-bathing medicinal vinegar for quickly treating dermatophytosis and preparation method thereof
  • Foot-bathing medicinal vinegar for quickly treating dermatophytosis and preparation method thereof
  • Foot-bathing medicinal vinegar for quickly treating dermatophytosis and preparation method thereof

Examples

  • Experimental program(7)

Example Embodiment

[0066] Example 1: Preparation of the foot bath medicated vinegar of the present invention (solid raw material per part by weight 1g, liquid raw material per part by weight 1mL)
[0067] Medicinal vinegar liquid raw materials: 20 parts of cork, 15 parts of Sophora flavescens, 20 parts of hibiscus bark, 5 parts of Chinese pepper, 500 parts of 95% ethanol (400 parts of which are used in mixed solvent), 240 parts of acetic acid, 160 parts of water, 2 parts Peppermint, 20 parts of benzoic acid, 50 parts of glycerin, appropriate amount of 75% ethanol;
[0068] Antibacterial powder raw materials: 300 parts of alum, 200 parts of boric acid, 200 parts of Smilax glabra, 150 parts of salt, 150 parts of talc.
[0069] Preparation of medicinal vinegar solution: pulverize 4 kinds of medicinal materials of Phellodendron chinense, Sophora flavescens, Prickly ash, and Zanthoxylum bungeanum to coarse particles, add solvent and immerse twice, the volume ratio is 95% ethanol: acetic acid: water = 5:3:2, first Add 500 parts by weight of solvent at one time, immerse for 72 hours, and filter; add 300 parts by weight of solvent for the second time and filter the residue for 48 hours, filter, combine the two filtrates, let stand for 24 hours, and then finely filter to obtain a brown extract ; Dissolve benzoic acid, menthol, and flavor in the remaining 95% ethanol, then add glycerin to mix, and then add to the above extract, stir evenly, dilute to 1000ml with 75% ethanol to obtain a medicated vinegar solution.
[0070] Preparation of antibacterial powder: pulverize alum, boric acid, smilax, salt, and talc into fine powders, pass through a 60-mesh sieve, and then mix and stir to obtain antibacterial powder.
[0071] The foot bath medicated vinegar product prepared in this example was evaluated by the Hunan Provincial Center for Disease Control and Prevention in accordance with the "Disinfection Technical Specifications" (2002 edition) for irritation response score and stimulus intensity evaluation. The foot bath medicated vinegar irritation index in this example is 0.167, which is no Irritating.

Example Embodiment

[0072] Example 2: Preparation of the foot bath medicated vinegar of the present invention (solid raw material per weight 1g, liquid raw material per weight 1mL)
[0073] Medicinal vinegar liquid raw materials: 10 parts of cork, 10 parts of Sophora flavescens, 10 parts of hibiscus bark, 1 part of Chinese pepper, 450 parts of 95% ethanol (300 parts of which are used for mixed solvent), 180 parts of acetic acid, 120 parts of water, 1 part Peppermint, 10 parts of benzoic acid, 80 parts of glycerin, appropriate amount of 75% ethanol;
[0074] Antibacterial powder raw materials: 200 parts of alum, 150 parts of boric acid, 150 parts of Smilax glabra, 100 parts of table salt, 400 parts of talc.
[0075] Preparation of medicinal vinegar solution: pulverize 4 kinds of medicinal materials of Phellodendron chinense, Sophora flavescens, Prickly ash, and Zanthoxylum bungeanum to coarse particles, add solvent and immerse twice, the volume ratio is 95% ethanol: acetic acid: water = 5:3:2, first Add 400 parts by weight of solvent at one time, immerse for 72 hours, and filter; add 200 parts by weight of solvent to the filter residue for the second time, soak for 48 hours, filter, combine the two filtrates, let stand for 24 hours, and then finely filter to obtain a brown extract ; Dissolve benzoic acid, menthol, and flavor in the remaining 95% ethanol, then add glycerin to mix, and then add to the above extract, stir evenly, dilute to 1000ml with 75% ethanol to obtain a medicated vinegar solution.
[0076] Preparation of antibacterial powder: pulverize alum, boric acid, smilax, salt, and talc into fine powders, pass through a 60-mesh sieve, and then mix and stir to obtain antibacterial powder.
[0077] The foot bath medicated vinegar product prepared in this example has been evaluated by the Hunan Provincial Center for Disease Control and Prevention in accordance with the "Disinfection Technical Specifications" (2002 Edition) for irritation response score and irritation intensity evaluation, which is non-irritating.

Example Embodiment

[0078] Example 3: Preparation of the foot bath medicated vinegar of the present invention (solid raw material per weight 1g, liquid raw material per weight 1mL)
[0079] Medicinal vinegar liquid raw materials: 30 parts of cork, 30 parts of Sophora flavescens, 30 parts of hibiscus bark, 10 parts of Chinese pepper, 550 parts of 95% ethanol (500 parts of which are used for mixed solvent), 300 parts of acetic acid, 200 parts of water, 5 parts Peppermint, 30 parts of benzoic acid, 10 parts of glycerin, appropriate amount of 75% ethanol;
[0080] Antibacterial powder raw materials: 100 parts of alum, 100 parts of boric acid, 100 parts of Smilax glabra, 300 parts of table salt, 100 parts of talc.
[0081] Preparation of medicinal vinegar solution: pulverize 4 kinds of medicinal materials of Phellodendron chinense, Sophora flavescens, Prickly ash, and Zanthoxylum bungeanum to coarse particles, add solvent and immerse twice, the volume ratio is 95% ethanol: acetic acid: water = 5:3:2, first Add 600 parts by weight of solvent at one time, immerse for 72 hours, and filter; add 400 parts by weight of solvent to the filter residue for the second time, soak for 48 hours, filter, combine the two filtrates, let stand for 24 hours, and then finely filter to obtain a brownish yellow extract ; Dissolve benzoic acid, menthol, and flavor in the remaining 95% ethanol, then add glycerin to mix, and then add to the above extract, stir evenly, dilute to 1000ml with 75% ethanol to obtain a medicated vinegar solution.
[0082] Preparation of antibacterial powder: pulverize alum, boric acid, smilax, salt, and talc into fine powders, pass through a 60-mesh sieve, and then mix and stir to obtain antibacterial powder.
[0083] The foot bath medicated vinegar product prepared in this example was evaluated by the Hunan Provincial Center for Disease Control and Prevention in accordance with the "Disinfection Technical Specifications" (2002 Edition) for irritation response scores and irritation intensity evaluations, which are non-irritating.
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Description & Claims & Application Information

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