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A preparation method and application of litchi core extract for preventing and treating prostate cancer

A prostate cancer, extract technology, applied in the directions of medical preparations containing active ingredients, food science, drug combination, etc., can solve the problem of low extraction rate, achieve strong dissolving ability, expand the scope and value of medicine, shorten processing effect of time

Active Publication Date: 2017-01-04
广西爱呗利生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problem of low extraction rate of existing extraction methods, the present invention provides a preparation method of litchi core extract for preventing and treating prostate cancer, and uses these active substances extracted from litchi core as raw materials for preparing functional food or medicine , applied to the adjuvant therapy or treatment of prostate cancer, thereby expanding the medicinal scope and value of litchi seed

Method used

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  • A preparation method and application of litchi core extract for preventing and treating prostate cancer
  • A preparation method and application of litchi core extract for preventing and treating prostate cancer
  • A preparation method and application of litchi core extract for preventing and treating prostate cancer

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Embodiment 1

[0038] A preparation method of litchi core extract for preventing and treating prostate cancer, comprising the following steps:

[0039]Step a, crush the lychee core to 20 meshes, add 3 times the amount of lychee core powder into an ethanol solution containing 0.5% acetic acid and a volume concentration of 50%, control the temperature at 50° C., and oscillate and stir for 24 hours at a pressure of 1 MPa, and then Ultrasonic treatment with a frequency of 20 kHz for 30 minutes, cooling to room temperature, and filtering to obtain the first filtrate and the first filter residue;

[0040] The larger the mesh number of crushing, the larger the surface area, and the higher the extraction efficiency, but if the mesh number is too large, the adsorption of active ingredients by litchi kernel powder will be stronger, so choose 20 mesh; ethanol as a polar organic solvent can dissolve extremely 50%-70% ethanol is suitable for extracting alkaloids, glycosides, etc. Adding acid to ethanol c...

Embodiment 2

[0049] A preparation method of litchi core extract for preventing and treating prostate cancer, comprising the following steps:

[0050] Step a, crush the lychee core to 20 meshes, add 3-4 times the volume concentration of 0.5% acetic acid in an ethanol solution containing 0.5% acetic acid, and control the temperature to 50-60 °C and the pressure to 1-2 MPa Shake and stir for 24 hours, then use ultrasonic treatment with a frequency of 20-30kHz for 30-45min, cool to room temperature, and filter to obtain the first filtrate and the first filter residue;

[0051] The larger the mesh number of crushing, the larger the surface area, and the higher the extraction efficiency, but if the mesh number is too large, the adsorption of active ingredients by litchi kernel powder will be stronger, so choose 20 mesh; ethanol as a polar organic solvent can dissolve extremely 50%-70% ethanol is suitable for extracting alkaloids, glycosides, etc. Adding acid to ethanol can promote the leaching o...

Embodiment 3

[0060] A preparation method of litchi core extract for preventing and treating prostate cancer, comprising the following steps:

[0061] Step a, crush the lychee core to 20 meshes, add 4 times the amount of lychee core powder into an ethanol solution containing 0.5% acetic acid and a volume concentration of 70%, control the temperature at 60° C., and oscillate and stir for 24 hours under a pressure of 2 MPa, then Ultrasonic treatment with a frequency of 30 kHz for 45 minutes, cooling to room temperature, and filtering to obtain the first filtrate and the first filter residue;

[0062] The larger the mesh number of crushing, the larger the surface area, and the higher the extraction efficiency, but if the mesh number is too large, the adsorption of active ingredients by litchi kernel powder will be stronger, so choose 20 mesh; ethanol as a polar organic solvent can dissolve extremely 50%-70% ethanol is suitable for extracting alkaloids, glycosides, etc. Adding acid to ethanol c...

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Abstract

The invention relates to a preparation method and application of litchi seed extract for preventing and treating prostate cancer, and belongs to the technical field of traditional Chinese medicine extracts. The present invention adopts dipping, ultrasonic, microwave, reflux extraction, extraction and other processes to fully destroy the cell wall, accelerate and increase the dissolution of active ingredients, and obtain the litchi core extract of the present invention. The extraction method has high efficiency and good quality of the extract, and can be directly Made into tablets, granules, powders, dripping pills, teas, decoctions, capsules, mixtures or syrups, etc., and added to related foods, beverages or medicines as functional additives for adjuvant therapy or treatment of prostate cancer, Thereby expanding the medicinal scope and value of litchi core.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine extracts, and in particular relates to a preparation method and application of litchi seed extracts for preventing and treating prostate cancer. Background technique [0002] Prostate cancer (PCa) is one of the most common malignant tumors of the genitourinary system in elderly men, and its morbidity and mortality rank second among male malignant tumors in Western countries, second only to lung cancer. In Shanghai, where the incidence rate of PCa is the highest in my country, the incidence rate in 2008 was as high as 29.02 per 100,000 people, ranking first among male genitourinary system tumors and fifth among all male tumors. With the improvement of the overall living standard of the people in our country and the change of lifestyle, the extension of the average life expectancy of men and the improvement of medical diagnosis technology, the incidence and detection rate of PCa...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/77A61P35/00A23L33/00
Inventor 郭宏伟张健卢奕夏玉对罗花
Owner 广西爱呗利生物科技有限公司
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