Method for preparing pain killer liniment containing short-pedicel aconite root

A technology of extraction liquid and ethanol, which is applied in the field of preparation of pain-relieving liniment, can solve the problems of poor stability and low extraction yield of main components

Inactive Publication Date: 2015-01-21
JIANGSU QILIKANG SKIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The purpose of the present invention is to solve the problems of low extraction yield of the main component and poor stability of the quick-acting analgesic liniment

Method used

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  • Method for preparing pain killer liniment containing short-pedicel aconite root

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A preparation method of an analgesic liniment containing Artemisia indica, comprising the steps of:

[0028] The 1st step, get Artemisia japonica 30Kg, Aconitum aconitum 10Kg, Aconitum aconiti 16Kg, Safflower 20Kg, after mixing uniformly, obtain mixture I, add the ethanol of 3 times weight of mixture I, the mass concentration of described ethanol is 60%, leached 1 time, and the time of leaching was 10 days, and the leaching solution was combined to obtain the first leaching solution;

[0029] The 2nd step, take gold leaf 10Kg, add water, heat extraction, the weight of water is 3 times of the weight of gold leaf, extraction time is 2h, obtains the second extraction liquid;

[0030] Step 3: Take 4Kg of frankincense, 5Kg of black bone, 3Kg of Chuanxiong, 5Kg of jintiesuo, 3Kg of Chonglou, 2Kg of aconite, 6Kg of Jianxuefei, and 20Kg of borneol, and grind them into particles with a diameter of 1cm. After mixing evenly, mixture II is obtained. 3 times the weight of ethanol o...

Embodiment 2

[0034] A preparation method of an analgesic liniment containing Artemisia indica, comprising the steps of:

[0035] The 1st step, get Artemisia japonica 50Kg, raw Aconitum 15Kg, raw Aconitum 20Kg, safflower 30Kg, after mixing uniformly, obtain mixture I, add the ethanol of 5 times weight of mixture I, the mass concentration of described ethanol is 70%, leached 3 times, and the time of leaching was 30 days, and the leaching solution was combined to obtain the first leaching solution;

[0036] The 2nd step, take gold leaf 15Kg, add water, heat extraction, the weight of water is 5 times of the weight of gold leaf, extraction time is 4 h, obtains the second extraction solution;

[0037] Step 3: Take 6Kg of frankincense, 10Kg of black bone, 6Kg of Rhizoma Chuanxiong, 15Kg of Jin Tiesuo, 5Kg of Chonglou, 4Kg of Aconite, 12Kg of Jianxuefei, and 25Kg of Borneol, and grind them into particles with a diameter of 3 cm. After mixing evenly, mixture II is obtained. Add 5 times the weight ...

Embodiment 3

[0041] A preparation method of an analgesic liniment containing Artemisia indica, comprising the steps of:

[0042] The 1st step, get Artemisia annua 40Kg, raw Aconitum 12Kg, Aconitum 18Kg, safflower 25Kg, after mixing uniformly, obtain mixture I, add the ethanol of 4 times weight of mixture I, the mass concentration of described ethanol is 65%, leached 2 times, and the time of leaching was 20 days, and the leaching solution was combined to obtain the first leaching solution;

[0043] The 2nd step, take gold leaf 12Kg, add water, heat extraction, the weight of water is 4 times of the weight of gold leaf, extraction time is 3h, obtains the second extraction solution;

[0044] Step 3: Take 5Kg of frankincense, 8Kg of black bone, 5Kg of Rhizoma Chuanxiong, 10Kg of Jin Tiesuo, 4Kg of Zhonglou, 3Kg of Aconite, 10Kg of Jianxuefei, and 22Kg of borneol, and grind them into particles with a diameter of 2 cm. After mixing evenly, mixture II is obtained. Add 4 times the weight of ethano...

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Abstract

The invention relates to a method for preparing a pain killer liniment containing short-pedicel aconite root, belonging to the technical field of traditional Chinese medicine external preparations. The method comprises the following steps: mixing short-pedicel aconite root, Radix Aconiti Kusenzoffii, radix aconite and red flower to be uniform, thereby obtaining a mixture I; adding the mixture I into ethanol, leaching, and merging the leaching solution, thereby obtaining a first leaching solution; adding water to yunnan craibiodendron leaf, and performing heating extraction, thereby obtaining a second leaching solution; respectively grinding frankincense, Forrest Silkvine Stem or Root, Ligusticum wallichii, Psammosilene tunicoides, Paris polyphylla, monkshood, Caesalpinia cucullata and borneol into granules, and mixing to be uniform, thereby obtaining a mixture II; adding the mixture II into ethanol, leaching, and merging the leaching solution, thereby obtaining a third leaching solution; merging the first leaching solution, the second leaching solution and the third leaching solution, and adjusting the mass concentration of ethanol, thereby obtaining the product. According to the pain killer liniment provided by the invention, the yunnan craibiodendron leaf is singly extracted by using water, so that the phenomenon that the stability of the major component, namely the short-pedicel aconite root, is influenced by impurities in the yunnan craibiodendron leaf can be avoided.

Description

[0001] technical field [0002] The invention relates to a preparation method of an analgesic liniment containing Artemisia indica, belonging to the technical field of traditional Chinese medicine preparations for external use. [0003] Background technique [0004] Physical pain has affected people's daily work and quality of life. In fact, pain is a disease. We should actively relieve pain scientifically, take correct drug treatment, and avoid misunderstandings. [0005] Topical analgesic and anti-inflammatory drugs act directly on the local area, and can reduce stomach discomfort caused by taking analgesics while ensuring good curative effect. Many pain treatment guidelines at home and abroad point out that topical analgesic and anti-inflammatory drugs are the first choice in the treatment of local pain such as neck, shoulder, low back pain, acute sprains, osteoarthritis of hands, knees, etc., and should be prescribed before using oral drugs. Consider using. Paink...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P29/00A61K31/045
CPCA61K36/714A61K9/0014A61K31/045A61K36/236A61K36/27A61K36/286A61K36/324A61K36/36A61K36/45A61K36/758A61K36/896
Inventor 吴克
Owner JIANGSU QILIKANG SKIN PHARMA
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