A kind of application of antsweed extract

Abstract

The invention discloses an application of an alysicarpus vaginalis extract in preparation of medicines, foods and healthcare products with a function of protecting liver injuries. Particularly, medicines, foods and healthcare products with the function of protecting acute or chronic liver injuries can be prepared. The alysicarpus vaginalis extract preferably is an ethyl acetate extract, and can be prepared into a plurality of dosage forms by adding pharmaceutical and food related carriers and auxiliary materials. A mice test result shows that the alysicarpus vaginalis extract is capable of obviously lowering CC14 and D-Ga1N and ALT and AST contents of acute liver injury mice serum, and obviously improving liver tissue pathological changes caused by CC14 and D-Ga1N, so as to play a protecting role.

Description

technical field

[0001] The invention belongs to the field of pharmacy, and specifically relates to the application of an antweed extract, in particular to the application of an antweed extract in the preparation of medicines, food and health care products for protecting liver damage. Background technique

[0002] Ant grass is the whole herb of Alysicarpus vaginalis (L.) DC., a leguminous plant. Native to South Asia and East Africa. Widely distributed in tropical regions of the Eastern Hemisphere. Hi tropical humid arid climate. Slightly drought-resistant, acid-resistant, not resistant to stains. It grows well on sandy loam, but is susceptible to nematodes, so it is usually planted on clay soil. The whole herb is sweet, bitter, flat; promoting blood circulation and dredging collaterals, clearing heat and dampness, resolving bone swelling; used for bruises, hemiplegia, femoral pain, hepatitis; snake bites, fractures, Bleeding from trauma, sores and festerings persist for ...

Examples

Embodiment 1

[0021] The preparation of embodiment 1 dog grass ethyl acetate extract

[0022] The specific steps are:

[0023] (1) Wash the dog antweed, ventilate and dry it at room temperature of 18-25°C, cut it into pieces and weigh it, and place it in an open reactor;

[0024] (2) Add 3-5 times 95% ethanol (v / v) to the open reactor to soak for 12-24 hours, then add 95% ethanol (v / v) to 10-15 times the amount of medicinal materials, and carry out reflux extraction;

[0025] (3) Keep boiling slightly for 2 hours, filter to obtain the first extract; after the medicinal material is cooled, add 10-15 times the amount of 95% ethanol (v / v) for the second time, keep boiling slightly for 1.5 hours, and get the second filtrate ; After the medicinal material is cooled, add 10-15 times the amount of 95% ethanol (v / v) for the third time and keep boiling slightly for 1 hour to obtain the third filtrate, combine the three extracts, and concentrate through a rotary evaporator to obtain the relative den...

Embodiment 2

[0029] Example Two Antweed Extract is processed into food and health products

[0030] 1. Vacuum-dry the ethanol extract of Trinidad antica, add starch, glucose and dietary fiber, stir well, coarsely crush to 60-80 mesh, pack in vacuum, and divide into 10g / bag to obtain its instant powder.

[0031] 2. Extract the ethanol-extracted extract of Trinidad antii with ethanol, evaporate the ethanol again until the content is less than 0.1%, add dietary fiber, malted milk extract, xylitol, flour, grind to 60-80 mesh in a grinder, add 5-10 % pure water, extruded to granulate, dried, sieved, packaged to obtain its granules.

[0032] 3. Add pure water to the extract of ethyl acetate extract of Trinoptera chinensis, stir to dissolve, add preservatives, honey, red bean juice, sterilize and sterilize, and then fill to obtain its liquid preparation.

[0033] 4. After drying, the extract obtained by supercritical fluid extraction of the whole plant of Antweed is added to coarse grain product...

technical field

[0001] The invention belongs to the field of pharmacy, and specifically relates to the application of an antweed extract, in particular to the application of an antweed extract in the preparation of medicines, food and health care products for protecting liver damage. Background technique

[0002] Ant grass is the whole herb of Alysicarpus vaginalis (L.) DC., a leguminous plant. Native to South Asia and East Africa. Widely distributed in tropical regions of the Eastern Hemisphere. Hi tropical humid arid climate. Slightly drought-resistant, acid-resistant, not resistant to stains. It grows well on sandy loam, but is susceptible to nematodes, so it is usually planted on clay soil. The whole herb is sweet, bitter, flat; promoting blood circulation and dredging collaterals, clearing heat and dampness, resolving bone swelling; used for bruises, hemiplegia, femoral pain, hepatitis; snake bites, fractures, Bleeding from trauma, sores and festerings persist for ...

Examples

Embodiment 1

[0021] The preparation of embodiment 1 dog grass ethyl acetate extract

[0022] The specific steps are:

[0023] (1) Wash the dog antweed, ventilate and dry it at room temperature of 18-25°C, cut it into pieces and weigh it, and place it in an open reactor;

[0024] (2) Add 3-5 times 95% ethanol (v / v) to the open reactor to soak for 12-24 hours, then add 95% ethanol (v / v) to 10-15 times the amount of medicinal materials, and carry out reflux extraction;

[0025] (3) Keep boiling slightly for 2 hours, filter to obtain the first extract; after the medicinal material is cooled, add 10-15 times the amount of 95% ethanol (v / v) for the second time, keep boiling slightly for 1.5 hours, and get the second filtrate ; After the medicinal material is cooled, add 10-15 times the amount of 95% ethanol (v / v) for the third time and keep boiling slightly for 1 hour to obtain the third filtrate, combine the three extracts, and concentrate through a rotary evaporator to obtain the relative den...

Embodiment 2

[0029] Example Two Antweed Extract is processed into food and health products

[0030] 1. Vacuum-dry the ethanol extract of Trinidad antica, add starch, glucose and dietary fiber, stir well, coarsely crush to 60-80 mesh, pack in vacuum, and divide into 10g / bag to obtain its instant powder.

[0031] 2. Extract the ethanol-extracted extract of Trinidad antii with ethanol, evaporate the ethanol again until the content is less than 0.1%, add dietary fiber, malted milk extract, xylitol, flour, grind to 60-80 mesh in a grinder, add 5-10 % pure water, extruded to granulate, dried, sieved, packaged to obtain its granules.

[0032] 3. Add pure water to the extract of ethyl acetate extract of Trinoptera chinensis, stir to dissolve, add preservatives, honey, red bean juice, sterilize and sterilize, and then fill to obtain its liquid preparation.

[0033] 4. After drying, the extract obtained by supercritical fluid extraction of the whole plant of Antweed is added to coarse grain product...