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Traditional Chinese medicine preparation used for treating silicosis, preparation method and application thereof

A technology of traditional Chinese medicine preparations and silicosis, which is applied in the direction of medical formulas, non-central analgesics, medical preparations containing active ingredients, etc., and can solve the problems of unresearched drug toxicity and lack of drug efficacy data, etc.

Inactive Publication Date: 2015-03-11
HANGZHOU HUQINGYUTANG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this traditional Chinese medicine has many components, and the curative effect after use is only superficially observed. It lacks the necessary efficacy data, and the toxicity of the drug has not been studied. Long-term use has a greater risk

Method used

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  • Traditional Chinese medicine preparation used for treating silicosis, preparation method and application thereof
  • Traditional Chinese medicine preparation used for treating silicosis, preparation method and application thereof
  • Traditional Chinese medicine preparation used for treating silicosis, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] The prescription is as follows:

[0042]

[0043] The operation is as follows:

[0044] Take the prescribed amount of Rhizoma Lisiana, add water to decoct twice, add 10 times the amount of water each time, decoct for 0.5 hours, and filter the decoction for the second time; Double the amount of water, 2 hours for the first time, 1 hour for the second time, and filter the juice for the second time. Combine the filtrates, precipitate for more than 8 hours, filter the supernatant, concentrate into a thick paste (d=1.143-1.167, 1→2, 20°C), put it in a clean container, and set aside. The extract is placed in a vacuum drying oven, dried under reduced pressure and low temperature to form a dry paste, and set aside. Get the dry extract and make granules, and mix into the granules prescription amount of petogenin (pass through 100 mesh after crushing), magnesium stearate, and talcum powder. Pressed finished product 1000 cores: core weight 0.35g / tablet. Sugar-coated or film...

Embodiment 2

[0046] The prescription is as follows:

[0047]

[0048] The operation is as follows:

[0049] Take the prescribed amount of Rhizoma Lisiana, add water to decoct twice, add 10 times the amount of water each time, decoct for 0.5 hours, and filter the decoction for the second time; Double the amount of water, 2 hours for the first time, 1 hour for the second time, and filter the juice for the second time. Combine the filtrates, precipitate for more than 8 hours, filter the supernatant, concentrate into a thick paste-like extract (d=1.143-1.167, 1→2, 20°C), put it in a clean container, and set aside. Add talcum powder and starch to the extract, mix well, and dry under reduced pressure and low temperature in a vacuum drying oven to form a dry paste, then make the dry paste into granules, and then mix in the prescribed amount of petogenin (after crushing, pass 100 order) and magnesium stearate to obtain corresponding granules after drying.

Embodiment 3

[0051] The prescription is as follows:

[0052]

[0053] The operation is as follows:

[0054] Take the prescribed amount of Rhizoma Lisiana, add water to decoct twice, add 10 times the amount of water each time, decoct for 0.5 hours, and filter the decoction for the second time; Double the amount of water, 2 hours for the first time, 1 hour for the second time, and filter the juice for the second time. Combine the filtrates, precipitate for more than 8 hours, filter the supernatant, concentrate into a thick paste (d=1.143-1.167, 1→2, 20°C), put it in a clean container, and set aside. The extract is placed in a vacuum drying oven, dried under reduced pressure and low temperature to form a dry paste, and set aside. Take the dry extract and make granules, mix into the granules the prescribed amount of petracenin (pass through 100 mesh after crushing), magnesium stearate, talcum powder and microcrystalline cellulose, mix evenly and pack into capsules to obtain the correspond...

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Abstract

The invention discloses a traditional Chinese medicine preparation used for treating silicosis, a preparation method and an application thereof. The traditional Chinese medicine preparation comprises the following raw materials by weight: 1250-2500 parts of Glechoma longituba, 750-1250 parts of gentrin knotweed, 30 parts of bergenin, 500-1000 parts of mulberry bark, 250-750 parts of fritillaria cirrhosa, 250-750 parts of stemona, 1-1.75 parts of auxiliary material magnesium stearate, 3.5-17.5 parts of powdered steatile, 3.5-17.5 parts of starch or 3.5-17.5 parts of dextrin, 3.5-17.5 parts of microcrystalline cellulose or 3.5-17.5 parts of mixture of starch, dextrin and microcrystalline cellulose. The traditional Chinese medicine preparation has the functions of invigorating blood circulation and dissipating binds, eliminating phlegm by cooling, as well as relieving cough and asthma. The tablet prepared by the traditional Chinese medicine preparation can be used for symptoms of cough, chest distress, short breath and hypodynamia due to silicosis; and can be used for acute attack sputum and heat cough patients of acute bronchitis and chronic bronchitis.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine preparation for treating silicosis and its preparation method and application. Background technique [0002] The lung is the main organ of the respiratory system. Its function is to perform gas exchange. In order to complete metabolism, the human body needs to continuously absorb oxygen from the air and expel carbon dioxide (gas exchange). This gas exchange is called breathing. Good lung function is the guarantee for maintaining life. However, with the aggravation of environmental pollution, there are more and more dust and harmful gases in the air, and more people are infected with various lung diseases, such as pneumoconiosis, chronic bronchitis and acute bronchitis. [0003] Silicosis, also known as silicosis, is the most common type of pneumoconiosis. It is caused by long-term inhalation of a large amount of f...

Claims

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Application Information

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IPC IPC(8): A61K36/704A61K36/904A61P11/00A61P11/14A61P11/06A61P11/10A61P29/00A61K31/366
CPCA61K31/366A61K9/1617A61K9/28A61K9/2806A61K9/48A61K9/4858A61K9/4866A61K36/53A61K36/605A61K36/704A61K36/8966A61K36/904A61K2236/331A61K2236/51A61K2300/00
Inventor 陈炜张伟韩俊琦
Owner HANGZHOU HUQINGYUTANG PHARM CO LTD
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