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Giant salamander grease compound burn medicine and preparation method thereof

A giant salamander oil and grease technology, which can be used in drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of declining market sales and less research on anti-inflammatory activities, and achieve easy application and uniformity. The effect of accelerating wound healing

Inactive Publication Date: 2015-04-22
ZUNYI MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, domestic and foreign research on the medicinal value of giant salamander is still in its infancy, and there are few studies on its anti-inflammatory activity, and the artificial breeding industry of giant salamander has entered a saturated state, and there are more and more wastes in the processing process. Enterprises urgently need to find new business opportunities for the development and utilization of giant salamanders. Therefore, the research on the medicinal development of giant salamander oil is an effective way to study the comprehensive utilization of waste and the new market growth point of the giant salamander industry.

Method used

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  • Giant salamander grease compound burn medicine and preparation method thereof
  • Giant salamander grease compound burn medicine and preparation method thereof
  • Giant salamander grease compound burn medicine and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A preparation method of giant salamander fat compound burn medicine, the steps are as follows:

[0037] Step 1: Select Coptidis 1g, Scutellaria baicalensis 1g, Frankincense 0.5g, Angelica dahurica 0.5g, Bletilla striata 0.5g and pulverize into coarse Chinese medicine powder for later use;

[0038] Step 2: soak the pulverized traditional Chinese medicine powder obtained in Step 1 with 15.624g sesame oil for 2 days, and set aside;

[0039] Step 3: Heat and decoct the soaked traditional Chinese medicine coarse powder obtained in Step 2 with a slow fire (110°C-130°C), and set aside;

[0040] Step 4: Filter the decocted Chinese medicine in step 3 with 4 layers of sterile gauze, take 6.1728g of the decocted and filtered upper oil layer Chinese medicine extract, and set aside;

[0041] Step 5: Add 6.1728g of the Chinese medicine extract obtained in Step 4 into 1.8172g of beeswax, autoclave for 30 minutes, and cool to 40°C for later use;

[0042] Step 6: Add 0.01g of borneol po...

Embodiment 2

[0044] A preparation method of giant salamander fat compound burn medicine, the steps are as follows:

[0045] Step 1: Select Coptidis 1g, Scutellaria baicalensis 1g, Frankincense 0.5g, Angelica dahurica 0.5g, Bletilla striata 0.5g and pulverize into coarse Chinese medicine powder for later use;

[0046] Step 2: Soak the pulverized traditional Chinese medicine powder obtained in Step 1 with 28.032g sesame oil for 2 days, and set aside;

[0047] Step 3: Heat and decoct the soaked traditional Chinese medicine coarse powder obtained in Step 2 with a slow fire (110°C-130°C), and set aside;

[0048] Step 4: Filter the decocted traditional Chinese medicine in step 3 with 4 layers of sterile gauze, take 10.1728g of the decocted and filtered upper oil layer Chinese medicine extract, and set aside;

[0049] Step 5: Add 10.1728 g of the traditional Chinese medicine extract obtained in Step 4 into 1.8172 g of beeswax, autoclave for 30 minutes, and cool to 40°C for later use;

[0050] S...

Embodiment 3

[0052] A preparation method of giant salamander fat compound burn medicine, the steps are as follows:

[0053] Step 1: Select Coptidis 1g, Scutellaria baicalensis 1g, Frankincense 0.5g, Angelica dahurica 0.5g, Bletilla striata 0.5g and pulverize into coarse Chinese medicine powder for later use;

[0054] Step 2: Soak the coarse powder of traditional Chinese medicine obtained in Step 1 with 40 g of sesame oil for 2 days, and set aside;

[0055] Step 3: Heat and decoct the soaked traditional Chinese medicine coarse powder obtained in Step 2 with a slow fire (110°C-130°C), and set aside;

[0056] Step 4: Filter the decocted Chinese medicine in step 3 with 4 layers of sterile gauze, take 14.1728g of the decocted and filtered upper oil layer Chinese medicine extract, and set aside;

[0057] Step 5: Add 14.1728 g of the traditional Chinese medicine extract obtained in Step 4 into 1.8172 g of beeswax, autoclave for 30 minutes, and cool to 40°C for later use;

[0058] Step 6: Add 0....

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PUM

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Abstract

The invention discloses giant salamander grease compound burn medicine and a preparation method of the giant salamander grease compound burn medicine. The giant salamander grease compound burn medicine comprises, by weight, coptis chinensis 1g, scutellaria baicalensis 1g, frankincense 0.5g, radix angelicae 0.5g, bletilla striata 0.5g, sesame oil 15.624g-40g, beewax 1.8172g, borneol 0.1g and giant salamander oil 4g-12g. The giant salamander grease compound burn medicine has the fragrance of the sesame oil. According to the giant salamander grease compound burn medicine, the special greasy sense can create moist environment and is beneficial to the release of multiple growth factors; migration rate and scabbing of epidermic cells are quickened; due to the dryness, wound epidermis tension force is strengthened, and therefore cicatrix growth is avoided and wound healing is quickened; an anoxic state created by the giant salamander grease compound burn medicine can restrain the growth of bacteria. The stability of the plaster is explained by the fact that unusual conditions such as delamination in a centrifuge model test and a heat - resistant and cold- resistant test do not occur. In an acute toxicity test, tissues such as the heart, the liver, the spleen, the lungs, the kidney, the brain, the intestine, the aorta, the thymus, the testis and the epididymis are not subject to pathologic change, which explains that the giant salamander grease compound burn medicine has no acute toxicity.

Description

technical field [0001] The invention relates to a medicine for external application for treating burns and scalds, and belongs to the field of traditional Chinese medicine for external use. Background technique [0002] Modern research proves that the early rational and effective use of anti-burn drugs is a key step in the treatment of burns and scalds. Western medicine and western medicine mainly use antibiotics to control infection in the "golden age" of burns and scalds, but there are disadvantages such as drug resistance and secondary damage. Such as silver sulfadiazine, its high-concentration preparations are more likely to damage cell activity and accelerate wound damage. Traditional Chinese medicine has a long history of treatment, and the effect of modern medicine and its preparations on burns (especially first-degree and second-degree burns) is ideal, which is significantly more effective than western medicine. Its treatment generally focuses on clearing heat and d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P17/02A61K35/65A61K31/045A61K35/644
CPCA61K9/06A61K31/045A61K35/644A61K35/65A61K36/185A61K36/232A61K36/324A61K36/539A61K36/718A61K36/898A61K2236/15A61K2236/35A61K2300/00
Inventor 王大忠李学英罗蔓莉
Owner ZUNYI MEDICAL UNIVERSITY
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