Metaplexis japonica C21 steroid extractive, and preparation method and application of metaplexis japonica C21 steroid extractive

A technology of extract and radish, which is applied in the field of medicine, can solve the problems of no research reports on tumor cell multidrug resistance reversal agents, no high-content radish C21 steroid extract products, etc.
CN104706698AInactive Publication Date: 2015-06-17QINGDAO UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
QINGDAO UNIV
Publication Date
2015-06-17
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a metaplexis japonica C21 steroid extractive, and a preparation method and an application of the metaplexis japonica C21 steroid extractive. The metaplexis japonica C21 steroid extractive is characterized in that dry metaplexis japonica rattan is extracted by a 0-100% alcohol solution, metaplexis japonica C21 steroids are separated by macroporous adsorption resin and decolorizing resin methods, and the weight percentage of C21 steroids is 50-95%. Proven by a research on pharmacological activities, the prepared metaplexis japonica C21 steroid extractive has the functions of reversing multiple drug resistance of a tumor, and can be used for preparing a tumor cell multi-drug resistance reversal agent.
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Description

technical field

[0001] The invention belongs to the field of medicine, and relates to a Radix Radix C21 steroid extract and a preparation method thereof, and also relates to the use of the Radix Radix Radix C21 steroid extract in preparing a tumor cell multidrug resistance reversal agent. Background technique

[0002] Malignant tumor is one of the diseases that seriously endanger human health. It is characterized by abnormal cell proliferation and metastasis. Statistics from the World Health Organization show that in 2000, there were about 10 million new cases of malignant tumors in the world, 6.2 million deaths, and 22 million cases of illness; it is estimated that by 2020, there will be 15 million new cases of malignant tumors, 10 million deaths, and 30 million illnesses. Thousands of cases. Chemotherapy is one of the methods of comprehensive therapy for malignant tumors. It is widely used before, during and after surgery. However, the phenomenon of multidrug resistance o...

Claims

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