A dynamic matrix control method for steam ejector sterilization based on data modeling

Abstract

The invention discloses a dynamic matrix control method for steam ejector sterilization based on data modeling, which takes the process of heating and sterilizing materials by a steam ejector as an object in the process of biopharmaceuticals, and takes the flow of steam at the inlet of the ejector as the control The temperature at the outlet of the ejector after the material and steam are mixed is the controlled amount, and the temperature at the inlet of the ejector material, the flow rate of the material, and the temperature of the steam inlet of the ejector are the disturbance quantities; this method establishes a system model based on industrial operating data, and based on the The obtained model obtains the step response of the control quantity and the step response of the disturbance quantity through system identification; establishes a dynamic matrix based on the system step response, and realizes the design of the controller for predictive control; the control method of the present invention is simple, and the analysis process and the controller The design is based on industrial process data, which reduces the dependence of the analysis and design process on sterilization equipment and related process links, and is easier to implement in engineering.

Description

technical field [0001] The invention belongs to the technical field of biological control, and in particular relates to a dynamic matrix control method for steam ejector sterilization based on data modeling. Background technique [0002] The continuous sterilization system and its device that use steam ejector to heat the medium are found in the biopharmaceutical production process. Under the control of the system, the material can be sterilized by steam during the flow of the disinfection pipeline, killing At the same time, the primary heat exchange is performed on the medium to raise the temperature, the tank is kept warm, and the secondary heat exchange is used to cool down, which provides a guarantee for the success of the subsequent fermentation process. Compared with the traditional solid tank disinfection, the continuous sterilization method heated by steam ejector is uninterrupted and efficient, the medium is heated evenly, the disinfection is thorough, and the amoun...

AI Technical Summary

Problems solved by technology

In the sterilization process, there are many links that affect the process parameters of the sterilization system, such as the temperature difference of the medium in the pipeline caused by the switching between different medium containers, that is, the material tanks, the specific heat capacity of different batches of medium, Inconsistencies in density and viscosity lead to changes in the flow rate of the medium in the pipeline and differences in heat transfer effects. The filters on the pipeline are clogged to varying degrees due to the operation of the system, which also affects the flow of the medium in the pipeline. The flow rate, and the disturbance of the steam pressure and temperature of the steam used for disinfection due to the sharing of multiple workshops, etc., all of the above factors have an impact on the precise control of the sterilization process, and make multiple process parameters not constant, making it difficult to use precise mathematics for this process. model to analyze

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