Use of penthorum chinense pursh extract in preparing medicines for treating hepatitis c

A technology of extracting and treating hepatitis C from yellow grass, which is applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of not treating and preventing hepatitis C with yellow grass, and achieve good preventive or therapeutic effect

Inactive Publication Date: 2015-08-19
SICHUAN JINYUNTANG CHINESE HERBAL PIECES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, there are no reports and related literatures on the treatment and prevention of Hepatitis C.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] (1) Take C. chinensis, remove the silt, impurities, moldy products and non-medicinal parts (roots) in the medicinal material of C. sativa, and obtain the pure medicinal material. Cut the above-mentioned clean medicinal materials of Huangcao into short sections (0.5-2.0 cm) to obtain decoction pieces of Huangcao, and put them into the extraction tank. Add 12 times the amount of purified water for the first time, decoct and extract for 2 hours, and filter while hot; add 10 times the amount of purified water for the second time, decoct and extract for 1 hour, and filter while hot; add 8 times the amount of purified water for the third time Purified water, boil and extract for 1 hour, filter while hot. The three filtrates were combined.

[0028] (2) Concentration: Concentrate the combined filtrate after decoction to a mixture with a relative density of 1.05 to 1.09 measured at 60°C to 70°C, and process it by centrifugation.

[0029](3) Alcohol precipitation: Put the...

Embodiment 2

[0032] (1) Take C. chinensis, remove the silt, impurities, moldy products and non-medicinal parts (roots) in the medicinal material of C. sativa, and obtain the pure medicinal material. Cut the above-mentioned clean medicinal materials of Huangcao into short sections (0.5-2.0 cm) to obtain decoction pieces of Huangcao, and put them into the extraction tank. Add 15 times the amount of purified water for the first time, decoct to extract for 2 hours, and filter while it is hot; add 12 times the amount of purified water for the second time, decoct and extract for 1 hour, and filter while it is hot; add 10 times the amount of purified water for the third time Purified water, boil and extract for 1 hour, filter while hot. The three filtrates were combined.

[0033] (2) Concentration: Concentrate the combined filtrate after decoction to a mixture with a relative density of 1.09 to 1.12 measured at 60 to 70°C, and process it by centrifugation.

[0034] (3) Alcohol precipitation:...

Embodiment 3

[0037] (1) Take C. chinensis, remove the silt, impurities, moldy products and non-medicinal parts (roots) in the medicinal material of C. sativa, and obtain the pure medicinal material. Cut the above-mentioned clean medicinal materials of Huangcao into short sections (0.5-2.0 cm) to obtain decoction pieces of Huangcao, and put them into the extraction tank. For the first time, add 18 times the amount of purified water, decoct and extract for 2 hours, and filter while it is hot; add 12 times the amount of purified water for the second time, decoct and extract for 1 hour, and filter while it is hot; add 8 times the amount of purified water for the third time Purified water, boil and extract for 1 hour, filter while hot. The three filtrates were combined.

[0038] (2) Concentration: Concentrate the combined filtrate after decoction to a mixture with a relative density of 1.02 to 1.05 measured at 60 to 70°C, and process it by centrifugation.

[0039] (3) Alcohol precipitation...

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PUM

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Abstract

The invention relates to new use of a penthorum chinense pursh extract, specifically relates to use of the penthorum chinense pursh extract in preparing medicines for treating hepatitis c and belongs to the fields of medicines and health care products. The penthorum chinense pursh extract is the water and / or ethanol extract of the penthorum chinense pursh and is applied to preparing the medicines for preventing or treating the hepatitis c; the penthorum chinense pursh extract is obtained by use of a water extraction and alcohol precipitation process; when the obtained penthorum chinense pursh extract is prepared into a form, the penthorum chinense pursh powder and the penthorum chinense pursh extract are taken as active ingredients and combined with accessories or auxiliary ingredients frequently used for health-care products or medicines, and all the mixed raw materials are prepared into a form for gastrointestinal absorption, wherein the form refers to oral liquid, powder, pill, tablet, granule or capsule. The penthorum chinense pursh extract has an excellent prevention or treatment effect on the hepatitis c and is capable of effectively reducing the level of each of ALT, AST, LDH, GGT, BIL, TBIL and TG in serum; as a result, a new option is provided for clinical medication for treating the hepatitis c.

Description

technical field [0001] The invention relates to a new application of an extract of C. chinensis, in particular to a use of an extract of C. chinensis in preparing a medicine for treating hepatitis C, and belongs to the field of medicines and health care products. Background technique [0002] Viral hepatitis C, referred to as hepatitis C, hepatitis C, is a viral hepatitis caused by hepatitis C virus (HCV) infection, mainly through blood transfusion, acupuncture, drug abuse, etc. According to the statistics of the World Health Organization, the global The infection rate of HCV is about 3%, it is estimated that about 180 million people are infected with HCV, and there are about 35,000 new cases of hepatitis C every year. Hepatitis C is a global epidemic, which can lead to chronic inflammation, necrosis and fibrosis of the liver, and some patients can develop liver cirrhosis and even hepatocellular carcinoma (HCC). Mortality associated with HCV infection (liver failure and de...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P1/16A61P31/14
Inventor 吴众
Owner SICHUAN JINYUNTANG CHINESE HERBAL PIECES
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