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Traditional Chinese medicine composition for treating chronic atrophic gastritis, preparation method and application thereof

A technology of atrophic gastritis and composition, which is applied in the field of prescriptions and traditional Chinese medicine preparations, and can solve problems such as refractory gastritis, high recurrence rate, and poor curative effect

Active Publication Date: 2018-07-20
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine often adopts anti-Helicobacter pylori, improving gastric motility, increasing mucosal nutrition and other methods for symptomatic treatment. The curative effect is poor, the recurrence rate is high, and it is difficult to cure

Method used

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  • Traditional Chinese medicine composition for treating chronic atrophic gastritis, preparation method and application thereof
  • Traditional Chinese medicine composition for treating chronic atrophic gastritis, preparation method and application thereof
  • Traditional Chinese medicine composition for treating chronic atrophic gastritis, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1 A kind of Chinese medicine composition (granule) for the treatment of chronic atrophic gastritis

[0019] The traditional Chinese medicine composition for the treatment of chronic atrophic gastritis described in this embodiment, its active ingredient is prepared from the following raw materials by weight: Radix Astragali 20g, Radix Pseudostellariae 10g, Atractylodes macrocephala 10g, Poria cocos 10g, Curcuma 9g, gecko 5g, white snake Tongue grass 15g, Hericium erinaceus 16g, Panax notoginseng 5g.

[0020] The preparation method of this Chinese medicine composition comprises the following steps:

[0021] (1) Gecko and Panax notoginseng are pulverized into medicinal material fine powder, and set aside;

[0022] (2) The zedoary extracts volatile oil, and the dregs are extracted with the astragalus, Radix Pseudostellariae, Atractylodes macrocephala, Poria cocos, Hedyotis diffusa, and Hericium erinaceus with water, filtered, and the extracts are combined, conce...

Embodiment 2

[0024] Embodiment 2 A kind of Chinese medicine composition (tablet) for the treatment of chronic atrophic gastritis

[0025] The traditional Chinese medicine composition for the treatment of chronic atrophic gastritis described in this embodiment, its active ingredient is prepared from the following raw materials by weight: Radix Astragali 20g, Radix Pseudostellariae 10g, Atractylodes macrocephala 10g, Poria cocos 10g, Curcuma 9g, gecko 5g, white snake Tongue grass 15g, Hericium erinaceus 16g, Panax notoginseng 5g.

[0026] The preparation method of this Chinese medicine composition comprises the following steps:

[0027] Step (1) and (2) are identical with the step (1) and (2) of embodiment 1;

[0028] (3) Take the extract described in step (2) and dry it into a dry extract, pulverize it, mix it with the fine powder of the medicinal material described in step (1), granulate it, add an appropriate amount of auxiliary materials, mix it, pass through a 100-mesh sieve, and dry p...

Embodiment 3

[0029] Embodiment 3 A kind of Chinese medicine composition (capsule) for the treatment of chronic atrophic gastritis

[0030] The traditional Chinese medicine composition for the treatment of chronic atrophic gastritis described in this embodiment, its active ingredient is prepared from the following raw materials by weight: Radix Astragali 20g, Radix Pseudostellariae 10g, Atractylodes macrocephala 10g, Poria cocos 10g, Curcuma 9g, gecko 5g, white snake Tongue grass 15g, Hericium erinaceus 16g, Panax notoginseng 5g.

[0031] The preparation method of this Chinese medicine composition is as follows:

[0032] Extract the astragalus, Radix Pseudostellariae, Atractylodes macrocephala, Curcuma, Poria, Hedyotis diffusa, Hericium erinaceus, Gecko, Panax notoginseng with water, filter the extracts, combine, concentrate to obtain extracts, dry into dry extracts, crush , add an appropriate amount of auxiliary materials, mix, pass through a 100-mesh sieve, dry-press or wet-granulate, dr...

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating chronic atrophic gastritis and a preparation method thereof. The active ingredients of the traditional Chinese medicinal composition for treating the chronic atrophic gastritis are prepared from the following raw materials in parts by weight: 10-30 parts of astragalus, 5-20 parts of radix pseudostellariae, 5-20 parts of white atractylodes rhizome, 5-20 parts of poria cocos, 5-20 parts of curcuma zedoary, 2-10 parts of gecko, 10-25 parts of hedyotis diffusa, 10-25 parts of hericium erinaceus and 3-10 parts of panax notoginseng powder. Commonly used auxiliary materials can be added into the traditional Chinese medicinal composition, and a common traditional Chinese medicinal preparation is prepared. The preparation method of the traditional Chinese medicinal composition comprises the following steps: smashing gecko and panax notoginseng powder into fine powder; extracting volatile oil from curcuma zedoary, extracting herb residue and residual raw materials with water, filtering, mixing extracting solution, and concentrating to obtain extract; drying the extract into dry extract, smashing, mixing with the fine powder, pelletizing, and adding the volatile oil, so that the traditional Chinese medicinal composition is obtained. Experiments prove that the traditional Chinese medicinal composition has the effect of preventing and treating the chronic atrophic gastritis and gastric precancerous lesions.

Description

technical field [0001] The invention belongs to the technical field of prescriptions and traditional Chinese medicine preparations, and more specifically, the invention relates to a traditional Chinese medicine composition for preventing and treating chronic atrophic gastritis, a preparation method and application thereof. Background technique [0002] Chronic atrophic gastritis (CAG) refers to Helicobacter pylori (Hp) infection, poor eating habits, immune abnormalities, intestinal fluid reflux, iron deficiency anemia, primary gastric disease migration and unhealed gastric mucosal epithelial and Chronic digestive system disease characterized by glandular atrophy (decreased number of glands, thinning of gastric mucosa, thickening of submucosal layer), intestinal metaplasia and / or dysplasia. The clinical manifestations are epigastric dull pain, fullness, heartburn, belching, anorexia, fatigue, weight loss, and anemia. CAG tends to occur in middle-aged and elderly people, and ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P1/04A61K35/583
Inventor 潘华峰曾进浩赵自明曾晓会严艳赵金媛林钟宇赖秋华
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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