Two-way infrared spectrum analysis system and testing method thereof

Abstract

The invention relates to a two-way infrared spectrum analysis system which comprises a two-way four-air-chamber light source, a first 12C air chamber, a second 12C air chamber, a first 12C detector, a second 12C detector, a first 13C air chamber, a second 13C air chamber, a first 13C detector, a second 13C detector, a signal processing device, a three-way exhaust valve, a first specimen suction pump, a second specimen suction pump, a first specimen suction control valve, a second specimen suction control valve, a first specimen container, a second specimen container and a double-head exhaust pump. The two-way four-air-chamber light source supplies pulse infrared signals to the first 12C air chamber, the second 12C air chamber, the first 13C air chamber and the second 13C air chamber. The invention further relates to a testing method of the two-way infrared spectrum analysis system. According to the two-way infrared spectrum analysis system and the testing method thereof, the testing performance is stable, the precision is high, and rapid point-of-care test can be performed on a patient expiration sample gas sample and a patient expiration original gas sample simultaneously.

Description

technical field [0001] The present invention relates to a 13 C An analysis system for breath test diagnosis of diseases, in particular to a dual-path infrared spectrum analysis system and a detection method thereof. Background technique [0002] The breath test is a non-invasive method for in vitro detection of labeled compounds after they are introduced into the body for metabolism. Stable isotope ratio analysis can be used in medicine to diagnose diseases. When the subject takes isotope-containing drugs, the metabolic function of the organism can be determined by measuring the isotope concentration or concentration ratio changes in the breath. Since 1987, Graham et al first reported the use of stable isotope carbon 13( 13 CO 2 ) to mark the urea breath test ( 13 Since the successful application of C-UBT to detect gastric Hp infection, the breath test has been widely used in the clinical detection and research of gastric Hp infection, liver reserve function, pancreatic ...

AI Technical Summary

Problems solved by technology

However, this infrared spectroscopic analysis technology is only equipped with a two-chamber detection unit. 13 When analyzing and testing C-UBT, it is first necessary to detect a group of subjects who have not taken 13 CO 2 The exhaled breath (original gas) before the urea reagent, and then test a group taking 13 CO 2 The exhaled gas (sample gas) after the urea reagent was analyzed by the infrared spectrum detection system of the two groups respectively, and the concentration in the exhaled gas before and after taking the medicine was calculated. 13 CO 2 Change amount to judge whether the subject is infected by gastric Helicobacter pylori

This method adopts sequential testing, the detection time is longer (3min / test), and the time span will also bring time difference drift, and this drift is very unfavorable for the detection of trace samples, and because of its irregularity It is very difficult to make up for it through data post-processing, which affects the stability and accuracy of the measurement.

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