Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Nano-hydroxyapatite/polyether-ether-ketone composite material and bone repair body as well as preparation method and application thereof

A nano-hydroxyapatite, hydroxyapatite technology, applied in the application and preparation of bone restorations, nano-hydroxyapatite/polyether ether ketone composite materials and its preparation field, can solve mechanical compatibility bone insufficiency Matching, inability to form osseointegration, lack of bioactivity and other problems, to achieve the effect of shortening bone healing time, good bioactivity and biocompatibility, and good biocompatibility

Inactive Publication Date: 2015-10-14
SHENZHEN KEJU NEW MATERIAL
View PDF2 Cites 20 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to overcome the mismatch between the mechanical compatibility of the existing bone repair materials and the bone, resulting in stress shielding, material loosening and bone resorption, resulting in too slow bone healing speed, or lack of biological activity, unable to For the defect of forming osseointegration, a nano-hydroxyapatite / polyether ether ketone composite material and its preparation method and application are provided, as well as a nano-hydroxyapatite / polyether ether ketone composite material. Bone prosthesis and method for its preparation

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Nano-hydroxyapatite/polyether-ether-ketone composite material and bone repair body as well as preparation method and application thereof
  • Nano-hydroxyapatite/polyether-ether-ketone composite material and bone repair body as well as preparation method and application thereof
  • Nano-hydroxyapatite/polyether-ether-ketone composite material and bone repair body as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] The preparation method of hydroxyapatite / polyether ether ketone composite material, it comprises the following steps:

[0051] Raw material: 3kg (30wt%) nanometer hydroxyapatite powder (particle diameter is 500nm) and 7kg (70wt%) polyether ether ketone powder (particle diameter is 10 μ m) are uniformly mixed in mixer, obtain mixed powder; Then use The injection molding machine injection-molded the mixed powder (using a mold of a non-bone prosthesis product) to obtain the product; wherein, the temperature of the injection molding was 365° C.; the pressure of the injection molding was 40 MPa. The mechanical properties of the nano-hydroxyapatite / polyether ether ketone composite are shown in Table 1.

Embodiment 2

[0053] The preparation method of nano-hydroxyapatite / polyether ether ketone composite material, it comprises the steps:

[0054] Raw materials: 3kg (30wt%) nano-hydroxyapatite powder (with a particle size of 500nm) and 7kg (70wt%) polyether ether ketone powder (with a particle size of 10 μm) were uniformly mixed in a mixer to obtain a mixed powder; Then use an injection molding machine to inject the mixed powder (using a mold for a non-bone prosthetic product) to obtain the product; wherein, the temperature of the injection molding is 370° C.; the pressure of the injection molding is 75 MPa. The mechanical properties of the hydroxyapatite / polyether ether ketone composite are shown in Table 1.

Embodiment 3

[0056] A method for preparing a bone prosthesis, comprising the steps of:

[0057] Raw material: 3.5kg (35wt%) nano-hydroxyapatite powder (particle diameter is 500nm) and 6.5kg (65wt%) polyetheretherketone powder (particle diameter is 15 μ m) carry out raw material uniform mixing in the mixer, obtain mixing powder; then use an injection molding machine to inject the mixed powder into a mold for dog alveolar bone prosthetics to obtain final product; wherein, the temperature of injection molding is 360° C.; the pressure of injection molding is 60 MPa. The mechanical properties of the bone restoration are shown in Table 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
particle diameteraaaaaaaaaa
particle diameteraaaaaaaaaa
particle diameteraaaaaaaaaa
Login to View More

Abstract

The invention discloses a nano-hydroxyapatite / polyether-ether-ketone composite material and a bone repair body as well as a preparation method and application thereof. The preparation method of the composite material comprises the following steps: uniformly mixing 30-35wt% of 200nm-1mu m hydroxyapatite powder and 65-70wt% of 5-15mu m polyether-ether-ketone powder to obtain mixed powder; and processing the mixed powder and moulding to obtain the composite material. The composite material has good biocompatibility and bioactivity as well as mechanical properties matching the bone tissue, effectively prevents the stress shielding effect, and can stimulate bone growth, accelerate bone healing, shorten the healing time of the injury after material implantation of bone and reduce the probability of second operation. The preparation technology of the composite material can be adjusted to prepare bone repair bodies different in shape, specification and mechanical properties to meet the clinical needs. Inflammatory reaction is avoided after the implantation of the bone repair bodies, the mechanical properties are matched with human bone, negative effects such as bone repair material loosening and bone resorption are prevented, and the clinical needs for bone repair can be met.

Description

technical field [0001] The invention relates to the field of polyether ether ketone composite materials, in particular to a nano-hydroxyapatite / polyether ether ketone composite material and its preparation method and application, and in particular to the application of a bone restoration and its preparation method. Background technique [0002] With the widespread application of bone implant materials, modern bone implant materials have higher and higher requirements for their biological functions, and the concept of osseointegration has been widely used in the evaluation of bone implants. [0003] At present, titanium-based and ceramic-based bone implant materials, which are widely used in clinical practice, have some shortcomings that are difficult to overcome. For example, the mechanical strength of metal and ceramic bone implant materials is much higher than that of bone tissue. Afterwards, stress shielding is prone to occur, which in turn causes bone resorption, bone at...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C08L61/16C08K3/32A61L27/46A61L27/50B29C45/78B29C45/77B29C59/00B29C67/04
Inventor 徐东马旭辉魏杰蔡亮张珏宋文华马瑞汤晓峰乔志龙周兵付俊祺
Owner SHENZHEN KEJU NEW MATERIAL
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com