Method and system for sensitivity analysis in modeling blood flow properties

A technology of blood flow characteristics and sensitivity, applied in the field of sensitivity analysis, can solve the problems of increased risk of patients, payment of health care expenses by patients, etc.

Active Publication Date: 2018-11-23
HEARTFLOW
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Therefore, CCA may result in unnecessary surgery being performed on the patient, which may pose increased risk to the patient and may result in the patient paying unnecessary health care costs

Method used

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  • Method and system for sensitivity analysis in modeling blood flow properties
  • Method and system for sensitivity analysis in modeling blood flow properties
  • Method and system for sensitivity analysis in modeling blood flow properties

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Embodiment Construction

[0019] Reference will now be made in detail to the exemplary embodiments, examples of which are illustrated in the accompanying drawings. Wherever possible, the same reference numbers will be used throughout the drawings to refer to the same or like parts.

[0020] In an exemplary embodiment, a method and system uses information obtained non-invasively from a patient to determine information related to blood flow in a particular patient. Various embodiments of such methods and systems are described in more detail in U.S. Patent No. 8,315,812, filed January 25, 2011 and entitled "Method and System for Patient-Specific Modeling of Blood Flow," cited in The method is incorporated into this article as a whole.

[0021] In some embodiments, the information determined by the disclosed methods and systems may relate to blood flow in the patient's coronary vasculature. Alternatively, the information determined may relate to blood flow within other regions of the patient's vasculatur...

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Abstract

Embodiments include systems and methods for determining cardiovascular information of a patient. A method includes receiving patient-specific data regarding the geometry of the patient's vasculature; creating an anatomical model representing at least a portion of the patient's vasculature based on the patient-specific data; and based on the anatomical model Create computational models of blood flow properties. The method also includes identifying one or more of an uncertain parameter, an uncertain clinical variable, and an uncertain geometry; modifying a probabilistic model; determining blood flow properties within the patient's vasculature based on the anatomical model of the patient's vasculature and the computational model of the blood flow properties; and based on the probabilistic model and The determined flow characteristics are used to calculate the sensitivity of the determined fractional flow reserve to one or more of the identified uncertain parameters, uncertain clinical variables, or uncertain geometries.

Description

[0001] priority [0002] This application claims priority to U.S. Application No. 13 / 864,996, filed April 17, 2013, which claims priority to U.S. Provisional Application No. 61 / 772,401, filed March 4, 2013, which Each is incorporated herein by reference in its entirety. technical field [0003] Embodiments of the present disclosure relate to methods and systems for patient-specific modeling of blood flow and, more particularly, to methods and systems for performing sensitivity analysis in patient-specific modeling of blood flow. Background technique [0004] Coronary artery disease can cause changes in the blood vessels that supply blood to the heart, such as stenosis (abnormal narrowing of blood vessels). As a result, blood flow to the heart may be restricted. Patients with coronary artery disease may experience chest pain, which is called chronic stable angina during strenuous physical activity or unstable angina when the patient is at rest. More severe disease manifest...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B6/00G06T7/00A61B5/02A61B5/026G06T17/00
CPCA61B6/504A61B5/02028A61B5/026G06T7/0012G06T2207/30104G06T2207/10081A61B6/5217A61B5/021A61B5/7278G16H50/50A61B5/02007A61B5/055A61B6/032
Inventor 塞瑟拉曼·桑卡兰莱昂·格雷迪查尔斯·A·泰勒
Owner HEARTFLOW
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