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Method and apparatus for generating widefield optical coherence volume tomograms

An optically coherent, wide-field-of-view technology, used in applications, medical science, equipment for testing eyes, etc., and can solve problems such as increasing acquisition time

Active Publication Date: 2018-02-02
CARL ZEISS MEDITEC INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method has the following limitations: (1) it requires a dedicated tracking module to detect eye movements during acquisition and maintain the relative position of each scan in order to generate functional OCT imaging data with a large field of view; Additional processing in real time during acquisition (motion detection and maintaining relative position for each scan), which can increase overall acquisition time; it requires synchronization between tracking system and acquisition system to handle motion, which can increase acquisition time

Method used

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  • Method and apparatus for generating widefield optical coherence volume tomograms
  • Method and apparatus for generating widefield optical coherence volume tomograms
  • Method and apparatus for generating widefield optical coherence volume tomograms

Examples

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no. 1 example

[0053] This example demonstrates a method for mapping two 3D tomogram scans acquired from a dual-source SD-OCT system to a common coordinate system generated using correlated fundus images to generate a wide-field optical coherence tomogram . For descriptive convenience only, one of the two input 3D volume tomograms is referred to as the reference optical coherence volume tomogram V R , while the other is called the target optical coherence volume tomogram V T . In typical dual-source SD-OCT, optical coherence tomography and fundus images are scanned simultaneously. Therefore the optical coherence volume tomogram and the associated fundus image should be considered to have been aligned in the same coordinate system after simultaneous scanning. Fundus images should cover a larger field of view (larger retinal area) than optical coherence tomography and OFI.

[0054] In this example, with V R The associated reference fundus image L R and V R is considered as the reference...

no. 2 example

[0078] This example demonstrates a method for mapping two optical coherence volume tomograms acquired from single-source OCT to a common coordinate system using correlated fundus images to generate a wide-field optical coherence volume tomogram. In single-source SD-OCT, optical coherence volume tomograms and fundus images are sequentially scanned separately, and the resulting optical coherence volume tomograms and their associated fundus images may not be in the same coordinate system, which is different from where the optical Unlike in dual-source OCT, coherent volume tomograms and their associated fundus images are always in the same coordinate system.

[0079] An input scan is considered to obtain a reference optical coherence volume tomogram V R , while the other is considered to obtain the target optical coherence volume tomogram V T .

[0080] Figure 7 A schematic flow diagram of the method presented in this example is shown.

[0081] In this example, the optical co...

no. 3 example

[0092] This example demonstrates a method for mapping more than two (e.g., 4) OCT optical coherence volume tomogram scans acquired from dual-source OCT into a common coordinate system generated using correlated fundus images to generate a wide field of view The method of optical coherence volume tomography.

[0093] Figure 8 An exemplary schematic diagram of the method demonstrated in this example is shown.

[0094] As shown in the figure, in step 801, a reference optical coherence volume tomogram V is selected from four optical coherence volume tomograms R .

[0095] In step 802, the remaining three non-reference optical coherence volume tomograms, that is, the target optical coherence volume tomograms, are respectively compared with the reference optical coherence volume tomograms V selected in step 801 R pair.

[0096] At step 803, for each pairing, the method presented in Example 1 can be applied to bring each non-reference (target) optical coherence volume tomogram i...

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Abstract

The invention discloses a method for generating a wide-field optical coherent volume tomogram of a retinal position, comprising: acquiring a plurality of optical coherent volume tomograms of different retinal positions and corresponding fundus images related thereto, a plurality of optical coherent volumes The tomogram includes a reference optical coherence volume tomogram (VR) and at least one target optical coherence volume tomogram (VT), and the corresponding fundus image includes a reference fundus image (LR) associated with the reference optical coherence volume tomogram and at least one target fundus image (LT) associated with at least one target optical coherence volume tomogram; registering the target fundus image (LT) with a reference fundus image (LR) to obtain a set of transformation parameters (P); and using the set The transformation parameter (P) maps the reference optical coherence volume tomogram (VR) and the target optical coherence volume tomogram (VT) associated with the target fundus image (LT) into a common coordinate system to obtain a wide-field optical coherence volume Chromatogram (VS).

Description

technical field [0001] The present invention relates to the field of retinal OCT (optical coherence tomography) imaging, more specifically, to a wide-field optical coherence volume tomogram (wide-field OCT three-dimensional volume tomogram, wide-field OCT volumetric image) method and device. Background technique [0002] OCT is a non-invasive tomographic imaging technique widely used in the diagnosis and treatment of retinal diseases. High axial resolution makes OCT particularly suitable for imaging stratified retinas. [0003] OCT is based on the principle of light interference and can be described as optical ultrasound. OCT measures the echo time delay and amplitude of reflected light from the imaged retinal tissue to generate high-resolution cross-sectional images of the retina, which can then be used to identify, monitor and quantitatively assess disease in different locations and layers of the retina . OCT is a type of interferometry that determines the scatter dist...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B3/12A61B3/14
Inventor G·D·乔希P·A·德赛R·K·马迪帕达加
Owner CARL ZEISS MEDITEC INC