A traditional Chinese medicine composition for treating cancer and its preparation method, preparation and application

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve the problems of high toxicity and side effects, increase of patients suffering from second tumors, mutagenic genotoxicity, etc., and achieve strong biological activity, significant anticancer effect, safety and effectiveness sex enhancing effect

Active Publication Date: 2017-11-03
KPC PHARM INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, Western medicine clinical treatment of tumors generally adopts three major treatment methods: surgical resection, radiotherapy, and chemotherapy. The curative effect is fast, but the toxic and side effects are large, which brings great pain to the patients.
In particular, chemical anticancer drugs often involve normal cells when they act on target cells, and some antitumor chemical drugs are often accompanied by varying degrees of mutagenic genotoxicity, resulting in an increase in patients suffering from the second disease while treating a certain tumor. possibility of tumor

Method used

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  • A traditional Chinese medicine composition for treating cancer and its preparation method, preparation and application
  • A traditional Chinese medicine composition for treating cancer and its preparation method, preparation and application

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preparation example Construction

[0063] The preparation method of Chinese medicine composition of the present invention comprises the following steps:

[0064] A. The roots of Zijinlong and Polygonum cuspidatum are crushed through a 10-50 mesh sieve, added with a mixed solvent of acetic acid-ethanol-water with a weight ratio of 2-3 times, soaked at 10-30°C for 4-8 hours, and transferred to a percolator. Percolation extraction with ethanol with a mass concentration of 30-70% of 5-7 times the weight ratio of the materials for 24-48 hours, collecting the percolation extract, filtering to obtain the filtrate a for later use;

[0065] B. Dianchangshan leaves, Hedyotis diffusa, Hatchling root, Prunella vulgaris, Lobelia, Rubia root, Scutellaria chinensis, Gentiana, Imperatae root are broken into 1~5cm, add ethanol with a mass concentration of 50~95% to extract, The extract is filtered to obtain the filtrate b for subsequent use;

[0066] C. Combine filtrate a and filtrate b, and vacuum spray dry at 40-60°C to obta...

Embodiment 1

[0073] The preparation of embodiment 1 Chinese medicine composition 1

[0074] 1. Origin and place of origin of medicinal materials

[0075] Hedyotis diffusa: It is the dried whole herb of Hedyotis diffusa, which is produced in Baoshan, Yunnan Province, and provided by Yixintang Chinese Herbal Medicine Co., Ltd. of Yunnan Province.

[0076] Bougainvillea root: It is the dry aboveground part of the Sanbaiaceae plant Bougainvillea, produced in Kunming, Yunnan Province, and provided by Yunnan Yixintang Chinese Herbal Medicine Co., Ltd.

[0077] Imperata Rhizome: It is the dried rhizome of Imperata praecox, which is produced in Chuxiong, Yunnan Province, and provided by Yixintang Chinese Herbal Medicine Co., Ltd. of Yunnan Province.

[0078] Gentian: It is the dried root and rhizome of Gentianae Gentiana, produced in Lincang, Yunnan, and provided by Yunnan Yixintang Chinese Herbal Medicine Co., Ltd.

[0079] Lobelia: the dried whole herb of Lobelia, a plant of Campanulaceae. Ha...

Embodiment 2

[0093] The preparation of embodiment 2 Chinese medicine composition 2

[0094] 1. Origin and place of origin of medicinal materials

[0095] With embodiment 1.

[0096] 2. Prescription

[0097] 52 parts of bar plate, 43 parts of lobelia, 35 parts of hedyotis diffusa

[0098] 51 parts of Yunnan Changshan leaves, 5 parts of Zijinlong root, 54 parts of madder root

[0099] 13 parts of Polygonum cuspidatum root, 63 parts of Imperata rhizome root, 49 parts of Huzu root

[0100] Gentian 19 parts Prunella vulgaris 41 parts

[0101] 3. Preparation method:

[0102] Step 1): Weigh Zijinlong root and Polygonum cuspidatum root according to the prescription, crush them through 50 meshes, add acetic acid-ethanol-water mixed solvent (0.5:30:69.5, m / m / m) twice the weight of the medicinal materials, Airtightly stand and soak for 4 hours, put it into a percolator, extract by percolation with 30% ethanol with a mass concentration of 7 times the weight of the material for 48 hours, collect ...

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Abstract

The invention discloses a traditional Chinese medicine composition as well as a preparation method, preparation and application thereof. The traditional Chinese medicine composition comprises 11-63 parts by weight of raw materials, 9-58 parts of Lobelia, 4-52 parts of Hedyotis diffusa, 13-76 parts of Dianchangshan leaves, 2-17 parts of Zijinlonggen 18~73 parts of Rubia root, 4~52 parts of Polygonum cuspidatum root, 19~75 parts of Imperata rhizome, 9~58 parts of Hatchling root, 11~63 parts of Gentiana and 5~57 parts of Prunella vulgaris, after pretreatment, extraction, Prepared by drying. The traditional Chinese medicine composition of the invention has the characteristics of multiple targets and multiple action channels, and has unique advantages in anti-cancer and anti-mutation. The traditional Chinese medicine composition of the invention has reasonable prescriptions, clear base sources of medicinal materials and clear application sites, scientific preparation method, clear and controllable quality indicators, high safety, remarkable curative effect, and broad application prospects.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine composition, a preparation method, preparation and application thereof. Background technique [0002] Cancer is a major disease that endangers human health in the world today. Its morbidity and mortality have been rising rapidly in recent years. The development of anticancer drugs has become a major topic of new drug research in this century. At present, Western medicine clinically treats tumors generally using three major treatment methods: surgical resection, radiotherapy, and chemotherapy. The curative effect is fast, but the toxic and side effects are large, which brings great pain to the patients. In particular, chemical anticancer drugs often involve normal cells when they act on target cells, and some antitumor chemical drugs are often accompanied by varying degrees of mutagenic genotoxicity, resulting in an increase in patients ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P35/00
Inventor 周荣光杨兆祥赵加强
Owner KPC PHARM INC
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