Traditional Chinese medicine for treating acute peptic ulcer bleeding and preparation method of traditional Chinese medicine

A technology for peptic ulcer and traditional Chinese medicine, applied in the field of pharmacy, can solve problems such as adverse reactions, safety doubts, and insignificant curative effects, and achieve definite curative effects.

Inactive Publication Date: 2015-12-16
徐保利
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in recent years, reports on the side effects of acid-suppressing drugs have been increasing. Some studies have pointed out that omeprazole can cause leukopenia, anaphylactic shock, arrhythmia, mental abnormalities and other serious adverse reactions.
Although the number of cases of this side effect is relatively rare, it also raises some questions about the safety of using the drug
In addition, the advantages of Western medicine in the treatment of this disease are mainly reflected in the hemostasis and the promotion of ulcer healing. For some common clinical symptoms, such as bloating, anorexia, dry mouth and bitter mouth, etc., the effect is not obvious, or has no effect, or even aggravates the symptoms Or produce related adverse reactions, which reduce the quality of life of patients to a certain extent

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0044] Wherein, when the dosage form of described Chinese medicine is powder, its preparation method comprises the following steps:

[0045] In the first step, the raw medicinal materials are mixed in proportion and pulverized into powder;

[0046] In the second step, the powder obtained in the first step is added to cold water and soaked for 6 hours to 12 hours, decocted with a slow fire for 3 hours to 5 hours, and the decoction is filtered to obtain the first filtrate. The quality of the powder is 2 to 4 times that of the powder obtained in the first step;

[0047] In the third step, add the filter residue obtained by the second step of filtration into cold water again, decoct with a slow fire for 2 hours to 4 hours, and filter to obtain the second filtrate. The quality of the added water is 2-2% of the quality of the filter residue obtained in the second step 4 times;

[0048] In the fourth step, the first filtrate obtained in the second step is mixed with the second filt...

Embodiment 1

[0055] Embodiment 1: Powder

[0056] Take 240g of female aster, 150g of millennium mugwort, 220g of loofah stalk, 240g of aloe vera root, 180g of clove Polygonum, 100g of Qilixiang, 90g of big arrow, 240g of Dongfeng vegetable, 140g of sweet potato root, 300g of Phnom Penh agave, 240g of Chiyangzi, 340g of wild peony , Caoduhuo 180g, womb cabbage 200g, Lingo 120g, kudzu root 230g and sea leek 140g;

[0057] Its preparation method comprises the following steps:

[0058] In the first step, the raw medicinal materials are mixed in proportion and pulverized into powder;

[0059] In the second step, add the powder obtained in the first step to soak in cold water for 10 hours, decoct with a slow fire for 4 hours, filter the decoction to obtain the first filtrate, the quality of the added water is the first step 2 times the mass of the powder obtained;

[0060] In the third step, the filter residue obtained by filtering in the second step is added to cold water again, decocted wit...

Embodiment 2

[0063] Embodiment 2: capsules

[0064] Take 220g of female aster, 180g of millennium mugwort, 200g of loofah root, 260g of aloe vera root, 140g of clove Polygonum, 150g of Qilixiang, 120g of big arrow, 200g of Dongfeng vegetable, 160g of sweet potato root, 260g of Phnom Penh agave, 260g of Chiyangzi, 320g of wild peony , 200g of Duhuo, 160g of Chinese cabbage, 170g of Lingo, 200g of bitter kudzu root and 170g of sea leek;

[0065] Its preparation method comprises the following steps:

[0066] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 95% that is three times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 95% relative to the quality of the dregs, heat and reflux for 2 hours, extract, and filter to obtain the second extract; combine the first extract and...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating acute peptic ulcer bleeding and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine is prepared from the following raw medicinal materials: aster fastigiatus, crossostephium chinense, luffa fruit pedicel, aloe root, ludwigia prostrate, root of lindley butterflybush, alisma canaliculatum, scabrous doellingeria rhizome and root, ficus tikoua, leaves of agave americana, fortune firethorn fruit, melastoma candidum, aralia yunnanensis, pakchoi seedling, malus formosana, pueraria omeiensis and triglochin martimum. The traditional Chinese medicine has the benefits that the traditional Chinese medicine can treat acute peptic ulcer bleeding and has the advantages of being definite in curative effect, quick to take effect and free of toxic and side effect.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating acute peptic ulcer bleeding and a preparation method thereof. Background technique [0002] Acute peptic ulcer bleeding mainly refers to ulcer bleeding that occurs in the stomach and duodenum, and is the most common cause of acute upper gastrointestinal bleeding, accounting for about 40-50%. Although most of the disease is self-limiting, and about 80% of the bleeding can be stopped by itself, but it is still potentially life-threatening. The occurrence of peripheral circulatory failure and hemorrhagic anemia can lead to death, and the mortality rate is about 10%. In addition, about 5% of bleeding cases are persistent bleeding, and 20%-25% of patients may rebleed within 48 hours of onset. These patients with persistent bleeding or rebleeding, as well as the elderly or those with serious complications The mortality rate of patients is h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P1/04A61P7/04
Inventor 徐保利张宪广
Owner 徐保利
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