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Female safety antimicrobial gel and preparation method thereof

A safe and gel-based technology, which can be used in pharmaceutical formulations, topical antibacterial agents, and medical preparations containing active ingredients, etc., can solve problems such as interference with female estrogen secretion system, rupture of vaginal and cervical epithelium, and invasion of pathogenic microorganisms. Improve the body's immunity, enhance phagocytosis, and inhibit side effects

Active Publication Date: 2015-12-23
HUBEI MULAN TONGDA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Condoms are currently the most widely used contraceptive tool, but some people may have safety problems such as allergies, rupture, slipping during sexual intercourse, etc.
Oral contraceptives interfere with female estrogen secretion system, making women not ovulate, so as to achieve the purpose of contraception, but it will cause adverse reactions such as nausea and vomiting in women
The existing external contraceptives are western medicines, which may cause rupture of vaginal and cervical epithelium, creating opportunities for pathogenic microorganisms to invade

Method used

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  • Female safety antimicrobial gel and preparation method thereof
  • Female safety antimicrobial gel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A kind of safe antibacterial gel for ladies comprises the following raw materials in parts by weight:

[0036] Material A: 0.1 part of carbomer, 1 part of polyethylene glycol, 68 parts of pure water;

[0037] Material B: 801 parts of Tween, 0.05 part of aloe extract, 0.05 part of benzalkonium chloride, 0.05 part of sodium hyaluronate, 0.1 part of triethanolamine;

[0038] Material C: 0.1 part of Genma, 1 part of octoxynol.

[0039] A preparation method of lady's safe antibacterial gel, comprising the following steps:

[0040]Step 1. Add 2 / 3 of the pure water in material A into the emulsification pot, slowly add carbomer, stir for 3 minutes, heat up to 40°C, stop heating, keep stirring for 1 hour, heat up to 60°C, keep stirring for 20 minutes, add Polyethylene glycol, heat preservation and stirring for 15 minutes, the rotation speed is 900r / min, and the temperature is lowered to 55°C;

[0041] Step 2. Use the pure water in material A to swell the sodium hyaluronate in...

Embodiment 2

[0044] A kind of safe antibacterial gel for ladies comprises the following raw materials in parts by weight:

[0045] Material A: 1.5 parts of carbomer, 15 parts of polyethylene glycol, 96 parts of pure water;

[0046] Material B: 806 parts of Tween, 1 part of aloe extract, 0.2 parts of benzalkonium chloride, 2 parts of sodium hyaluronate, 1.5 parts of triethanolamine;

[0047] Material C: 0.5 parts of Genma, 3.5 parts of octoxynol.

[0048] A preparation method of lady's safe antibacterial gel, comprising the following steps:

[0049] Step 1. Add 2 / 3 of the pure water in material A into the emulsification pot, slowly add carbomer, stir for 5 minutes, heat up to 40°C, stop heating, keep stirring for 1.5h, heat up to 70°C, keep stirring for 20 minutes, Add polyethylene glycol, keep stirring for 15 minutes, rotate at 900r / min, and cool down to 55°C;

[0050] Step 2. Use the pure water in material A to swell the sodium hyaluronate in material B in advance, add Tween 80 to the ...

Embodiment 3

[0053] A kind of safe antibacterial gel for ladies comprises the following raw materials in parts by weight:

[0054] Material A: 1 part of carbomer, 8 parts of polyethylene glycol, 82 parts of pure water;

[0055] Material B: 804 parts of Tween, 0.5 part of aloe extract, 0.12 part of benzalkonium chloride, 1 part of sodium hyaluronate, 0.8 part of triethanolamine;

[0056] Material C: 0.3 parts of Genma, 2.5 parts of octoxynol.

[0057] A preparation method of lady's safe antibacterial gel, comprising the following steps:

[0058] Step 1. Add 2 / 3 of the pure water in material A into the emulsification pot, slowly add carbomer, stir for 4 minutes, heat up to 40°C, stop heating, keep stirring for 1 hour, heat up to 65°C, keep stirring for 20 minutes, add Polyethylene glycol, heat preservation and stirring for 15 minutes, the rotation speed is 900r / min, and the temperature is lowered to 55°C;

[0059] Step 2. Use the pure water in material A to swell the sodium hyaluronate in...

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Abstract

The invention discloses female safety antimicrobial gel. The female safety antimicrobial gel is prepared from materials A including, by weight, 0.1-1.5 parts of carbomer, 1-15 parts of polyethylene glycol and 68-96 parts of purified water, materials B including, by weight, 1-6 parts of tween 80, 0.05-1 part of aloe extract, 0.05-0.2 part of benzalkonium chloride, 0.05-2 parts of sodium hyaluronate and 0.1-1.5 parts of triethanolamine, and materials C including, by weight, 0.1-0.5 part of germall and 1-3.5 parts of octoxynol. The invention further discloses a preparation method of the female safety antimicrobial gel. The female safety antimicrobial gel can kill sperms, prevent pregnancy, conduct sterilization and disinfection and prevent reproductive tract infections, is small in vagina stimulation and has the two-way protection function.

Description

technical field [0001] The invention relates to female care products, in particular to a safe antibacterial gel for women and a preparation method thereof. Background technique [0002] my country has a large population, and family planning is the basic national policy of our country. It is of great significance to develop family planning products that are safe, effective, convenient to use, have no side effects on the human body, have market promotion value, and can be mass-produced. Currently commonly used contraceptive methods are rubber condoms, oral contraceptives and external contraceptives. Condoms are currently the most widely used contraceptive tool, but some people may have safety problems such as allergies, rupture, and slippage during sexual intercourse. Oral contraceptives interfere with the female estrogen secretion system, causing women to not ovulate, so as to achieve the purpose of contraception, but they will cause adverse reactions such as nausea and vomi...

Claims

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Application Information

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IPC IPC(8): A61K36/886A61K36/896A61K9/06A61K36/902A61P15/00A61P15/08A61P31/02
Inventor 夏穆兰宋铜山
Owner HUBEI MULAN TONGDA TECH
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