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Brain template generating method

A technology of brain templates and standard brain templates, applied in the field of medical image processing, can solve problems such as brain function and structure positioning errors, mistakes, and restrictions on brain function and structure research

Inactive Publication Date: 2016-01-06
XUANWU HOSPITAL OF CAPITAL UNIV OF MEDICAL SCI
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Problems solved by technology

However, these brain templates are either derived from individual human cadaver data, or from a single or small-scale brain image sample. When applied to subjects of different ages, genders, and ethnic groups, large deviations will occur. This has become a major problem restricting the study of brain function and structure
Furthermore, there is no unified Chinese standard brain template for Chinese people. Therefore, in clinical applications, when judging whether the collected brain images are abnormal, it can only be determined by comparing them with the standard brain templates of Westerners; In scientific research, when conducting group analysis, the Chinese brain can only be registered to the Western brain template to report the research results. Due to the significant differences in the morphology of the Eastern and Western brains, it often leads to inaccurate diagnosis and errors in the positioning of brain functions and structures, or even errors

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Embodiment Construction

[0026] In order to make the objectives, technical solutions and advantages of the present invention clearer, the present invention will be further described in detail below with reference to the accompanying drawings and embodiments.

[0027] It can be seen from the background technology that the existing standard brain templates have defects such as small sample size, no distinction of different genders and ages, and mainly reflect the characteristics of the brains of Westerners, and are not established for the Chinese. Therefore, based on the standard brain When the template is used to judge the abnormality or pathological changes of the collected Chinese human brain images, it will produce a large error in the positioning of the brain function and structure. Therefore, the method for generating a brain template provided by the embodiment of the present invention first collects a set of thousands of MRI images of the Chinese human brain, and then, based on the collected Chinese ...

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Abstract

The invention discloses a brain template generating method. The method includes the steps of firstly, collecting thousand-level-quantity Chinese brain MRI images; secondly, screening and normalizing on the basis of the collected Chinese brain MRI images to generate standard brain templates, wherein the generated standard brain templates include brain templates corresponding to different ages and genders and brain tissue probability graphs corresponding to the brain templates. By the method, the standard brain templates for Chinese can be built, and clinical application and brain science researches are supported.

Description

Technical field [0001] The invention relates to medical image processing technology, in particular to a method for generating brain templates. Background technique [0002] Despite the rapid development of science and technology, human beings still have little understanding of the origin of consciousness and thinking, the material basis of intelligence and creativity. At the same time, with the increasing number of neurological and mental diseases that seriously endanger human health, people urgently need to understand the brain structure, specifically, what is the brain structure in a normal state, and what is the law of brain structure development and degeneration. Therefore, building a human brain template has become the fundamental core of solving the above problems. [0003] At present, there have been some researches on the standard brain template, that is, the brain template is obtained after processing the brain image. However, these brain templates are derived from indiv...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/055G06V10/772
CPCG01R33/5608G06T7/35A61B5/0042A61B5/055A61B2576/026G06T2207/30016G06T2207/10088G16H30/40G06V10/772G06F18/28
Inventor 李坤成梁佩鹏王德峰石林
Owner XUANWU HOSPITAL OF CAPITAL UNIV OF MEDICAL SCI
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