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Medicinal composition for treating asthma and application thereof

A composition and drug technology, applied in the field of pharmaceutical compositions for the treatment of asthma, can solve the problems of untimely treatment, large adverse reactions, arrhythmia, etc., and achieve the effect of lasting effect, high safety, and improving lung function

Inactive Publication Date: 2016-01-20
庄小侃
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This new formulation for treating respiratory disorders caused by breathing problems or symptoms such as wheeziness (bronchosis) also improves its efficacy compared to previous methods like drugs alone. Overall this results in longer lastings between treatment sessions while reducing their negative impact on healthy individuals who are taking them regularly over time.

Problems solved by technology

The technical problem addressed in this patents relates to finding effective methods or agents against respiratory diseases such as bronchitis caused by common allergens like grass pollen allergy, which has become increasingly prevalence over recent years due to changes made during urbanization patterns throughout Western Europe. Current therapies involve symptom relief with sterile saliva containing beta-2 blockers, corticosteroids, etc., while others focus more heavily on prevention measures involving regular administration of these substances at specific doses.

Method used

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  • Medicinal composition for treating asthma and application thereof
  • Medicinal composition for treating asthma and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] The preparation of embodiment 1 Chinese medicine dry ointment powder

[0015] Weigh juvenile red 1.2kg, sword bean 1.8kg, acacia seed 0.7kg, basil 0.8kg, terrestris flower 0.8kg, alder bark 1.2kg, acacia bark 1.0kg, Baiwei 1.0kg, magnolia 0.8kg, holy basil 0.8kg and Yulinghua 0.8kg, put it in a sandwich pot and mix evenly, add water to cover the medicinal surface 2cm, soak for 30 minutes, heat to boil, then simmer for 1 hour, filter after cooling, add water 10 times the total mass of the medicinal materials to the filter residue After heating and boiling, decoct with low heat for 1 hour, then filter, combine the two filtrates, concentrate to obtain extract, dry at 80°C to obtain dry extract, and then crush the dry extract into fine powder of 120 mesh to obtain dry extract powder of traditional Chinese medicine extract.

Embodiment 2

[0016] The preparation of embodiment 2 Chinese medicine dry ointment powder

[0017] Weigh juvenile red 1.5kg, sword bean 1.9kg, acacia seed 0.8kg, basil 0.9kg, terrestris flower 0.9kg, alder bark 1.5kg, acacia bark 0.9kg, Baiwei 0.9kg, magnolia 0.7kg, holy basil 0.7kg Put 0.7kg of jade bell flowers in a sandwich pot and mix evenly, add water to cover the medicine surface 2cm, soak for 30 minutes, heat to boil, then simmer for 1h, cool and filter, add appropriate amount of water to the filter residue, heat to boil, then simmer for 1h , and then filtered, the two filtrates were combined, concentrated into an extract, dried at 80°C to obtain a dry extract, and then the dry extract was crushed into a fine powder of 120 mesh to obtain a dry extract powder of the Chinese medicine extract.

Embodiment 3

[0018] The curative effect research of embodiment 3 Chinese medicine extracts to asthmatic rats

[0019] 40 clean-grade SD rats, with a body weight ranging from 180 to 220 g, were fed adaptively for one week, and all rats were randomly divided into normal group, model group, and low-dose and high-dose Chinese medicine extract groups, with 10 rats in each group, male and female Half and half. Except for the normal group, rats in other groups were sensitized with ovalbumin (OVA) to prepare animal models of bronchial asthma. The method was as follows: 3 Dry powder 100mg normal saline suspension 1mL intraperitoneal injection for sensitization, repeat the sensitization once on the 8th day, start ultrasonic atomization 1% 0VA to stimulate from the 15th day, about 30min / time, at 8-9 am every day Proceed, and end the stimulation operation in the 4th week. During nebulization, the rats were found to have symptoms such as irritability, sneezing, incontinence, ear scratching, and cyano...

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Abstract

The invention relates to a medicinal composition for treating asthma and application thereof. The medicinal composition is prepared from, by weight, 9-15 parts of ardisia alyxiaefolia, 14-21 parts of sword beans, 6-9 parts of Chinese honeylocust seeds, 6-10 parts of sessile stemona roots, 6-10 parts of tribulus terrestris fruits, 10-15 parts of alder bark, 8-12 parts of cortex albiziae, 8-12 parts of blackend swallowwort roots, 6-9 parts of biond magnolia flowers, 6-9 parts of ocimum tenuiflorum and 6-9 parts of fragrant snowbell. The medicinal composition can improve the lung function of a patient suffering from bronchial asthma and improve asthma airway remodeling, the action is lasting, no side effect is caused, the curative effect is consolidated, and thus the purpose of curing asthma is achieved.

Description

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Claims

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Application Information

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Owner 庄小侃
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