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Medicine composition for treating leucoderma and preparation method thereof

A composition and technology of vitiligo, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve problems such as adverse reactions and long course of disease

Inactive Publication Date: 2016-02-03
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, due to the long course of the disease, long-term oral administration of this drug can also cause serious adverse reactions. Therefore, clinical research on the efficacy of traditional Chinese medicine in the treatment of vitiligo has always attracted attention.

Method used

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  • Medicine composition for treating leucoderma and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1: the pharmaceutical composition for the treatment of vitiligo and its preparation method

[0031] The composition and parts by weight of the raw material drug of the medicinal composition for treating vitiligo are: plateau flea 110g stipola 90g annonaline 6g cassia japonica 3g coreopsis chalcone 2.5g;

[0032] Preparation method: according to the ratio of raw materials, take plateau flea, stipola, cinnamon, grass jade plum, and coreopsis chalcone, mix well, use 35% ethanol as a solvent, and extract by warm soaking at 30°C , the number of times of extraction is 4 times, each extraction time is 3 hours, each solvent consumption is 14 times of the total weight of the crude drug, filtered, and the dregs A and the extract are obtained, the extract reclaims ethanol, and is concentrated to a relative density of 1.20, Filtration, the medicinal solution passes through the DM130 macroporous adsorption resin column, firstly elutes with water, then elutes the DM130 mac...

Embodiment 2

[0033] Embodiment 2: the pharmaceutical composition for the treatment of vitiligo and its preparation method

[0034] The composition and parts by weight of the raw material drug of the medicinal composition for treating vitiligo are: plateau flea 100g stipulina 100g annonaline 5g cassia japonica 4g coreopsis chalcone 2g;

[0035] Preparation method: according to the ratio of raw materials, take plateau flea, stipola, cinnamon, grass jade plum, and coreopsis chalcone, mix well, use 35% ethanol as a solvent, and extract by warm soaking at 30°C , the number of times of extraction is 4 times, each extraction time is 3 hours, each solvent consumption is 14 times of the total weight of the crude drug, filtered, and the dregs A and the extract are obtained, the extract reclaims ethanol, and is concentrated to a relative density of 1.20, Filtration, the medicinal solution passes through the DM130 macroporous adsorption resin column, firstly elutes with water, then elutes the DM130 ma...

Embodiment 3

[0036] Embodiment 3: the pharmaceutical composition for the treatment of vitiligo and its preparation method

[0037] The composition and parts by weight of the raw material drug of the medicinal composition for treating vitiligo are: plateau flea 120g stipulina 80g annonaline 7g grass jade plum 2g coreopsis chalcone 3g;

[0038] Preparation method: according to the ratio of raw materials, take plateau flea, stipola, cinnamon, grass jade plum, and coreopsis chalcone, mix well, use 35% ethanol as a solvent, and extract by warm soaking at 30°C , the number of times of extraction is 4 times, each extraction time is 3 hours, each solvent consumption is 14 times of the total weight of the crude drug, filtered, and the dregs A and the extract are obtained, the extract reclaims ethanol, and is concentrated to a relative density of 1.20, Filtration, the medicinal solution passes through the DM130 macroporous adsorption resin column, firstly elutes with water, then elutes the DM130 mac...

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Abstract

The invention discloses a medicine composition for treating leucoderma and a preparation method thereof. The medicine composition disclosed by the invention is prepared from the raw medicinal materials: aernaria przewalskii maxim, semen caesalpiniae cristae, anonaine, anemone rivularis and Okanin in proportion, can be prepared into various dosage forms according to a conventional preparation process, and has a remarkable curative effect on leucoderma.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a medicinal composition for treating vitiligo and a preparation method thereof. Background technique [0002] Vitiligo is a common acquired localized or generalized skin depigmentation disease. Due to the loss of melanocyte function in the skin, it can occur in various parts of the body, and it is common in the back of the fingers, wrists, forearms, face, neck and around the genitals. There is no obvious gender difference in the incidence of this disease, and it can occur in all age groups, but it is more common in adolescents. The skin lesions are depigmented spots, usually milky white or light pink, with smooth surface and no rash. The boundary of the leukoplakia is clear, the pigment at the edge is increased compared with normal skin, and the hair in the leukoplakia is normal or white. The lesions tend to occur in the parts damaged by sunli...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61P17/00A61K31/12A61K31/473
Inventor 邵培财
Owner JINAN XINGYI MEDICAL TECH
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