Application of sambucus chinensis extract in preparing medicine for treating brain blood circulation disturbance

A technology of blood circulation disorder and elderberry, which is applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of rising stroke mortality and other problems

Inactive Publication Date: 2016-03-09
赵利锋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The mortality rate of stroke also tends to increase with age, due to the lack of effective treatment measures

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Extraction of elderberry extract: adding 70% ethanol with 25 times the weight of medicinal material, heating and reflux extraction, the extraction times is 3 times; concentrating and drying under reduced pressure to obtain elderberry extract.

[0014] Superoxide dismutase (SOD) and reduced glutathione (GSH) play a vital role in the body's oxidation and antioxidant balance, which can scavenge superoxide anion free radicals and protect cells from damage. Experiments of the present invention show that the elderberry extract can increase the activities of superoxide dismutase (SOD) and reduced glutathione (GSH).

[0015] Table 1 and Table 2 are the levels of GSH and SOD in cortical cells and brain tissue respectively. The results show that elderberry extract can increase the activity of superoxide dismutase (SOD) and reduced glutathione (GSH).

[0016] Table 1

[0017] group GSH SD SOD SD control group 100 0 100 0 glutamate group 52.16 9.34...

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Abstract

The invention discloses application of a sambucus chinensis extract in preparing a medicine for treating brain blood circulation disturbance. The brain blood circulation disturbance refers to cerebral apoplexy. The sambucus chinensis extract is capable of reducing neurotoxicity caused by glutamic acid, reducing cortical neuron damage caused by oxygen-glucose deprivation, increasing the activity of glutathione peroxidase and superoxide disumtase in cortical neuronal cells and brain tissues and reducing the volume of cerebral ischemia infarction after cerebral apoplexy.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, and more specifically relates to the application of an elderberry extract in the preparation of a medicine for treating brain blood circulation disorders. Background technique [0002] Cerebral stroke is a group of diseases with cerebral ischemia and hemorrhagic injury symptoms as the main clinical manifestations, also known as stroke or cerebrovascular accident, with a very high mortality rate and disability rate, mainly divided into hemorrhagic stroke ( Cerebral hemorrhage or subarachnoid hemorrhage) and ischemic stroke (cerebral infarction, cerebral thrombosis), with cerebral infarction being the most common. Cerebral stroke is one of the most important fatal diseases in the world, with acute onset and high mortality rate. The mortality rate of stroke also tends to increase with age, because there has been a lack of effective treatment measures. [0003] Elderberry (Latin scientif...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P9/10A61P25/00
Inventor 赵利锋
Owner 赵利锋
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