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Traditional Chinese medicine composition for treating insomnia and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and preparation thereof, can solve the problems of no special effect, recurrence and the like, and achieve the effects of simple prescription, prolonging sleep time, and strengthening hypnotic effect

Inactive Publication Date: 2016-05-11
宋淑芹
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern medicine has no specific effect on insomnia. Western medicines are mostly maintained with anti-anxiety and sedative-hypnotic drugs. If the drug is stopped, the recurrence will be even more serious. After taking these drugs for a long time, the patient will have side effects such as headache, dizziness, nausea, gastrointestinal discomfort, and body weakness.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Preparation of crude drug powder

[0028] Wash Zijinlong, Shichangpu and Chuanxiong separately, dry them, chop them, crush them through a 60-mesh sieve, and weigh three medicinal powders according to the following weight ratio: Zijinlong 200g, Shichangpu 120g, Chuanxiong 40g, mix well, that is Prepare crude drug powder.

Embodiment 2

[0030] Preparation of capsules

[0031] Wash the three kinds of medicinal materials in the prescription, dry them in the air, chop them up, and pass through a 60-mesh sieve.

[0032] Weigh three medicinal material powders according to the following weight ratio: Zijinlong 200g, Shichangpu 120g, Chuanxiong 40g, add microcrystalline cellulose 30g, magnesium stearate 2g, and mix well.

[0033] The above-mentioned mixture powder is packed into No. 0 capsules (about 0.4g), a total of 1000 capsules.

Embodiment 3

[0035] Preparation of Active Ingredient Solution

[0036] Take 100g Zijinlong, 50g Shichangpu, and 30g Chuanxiong, add water to decoct twice, each time add water 8 times the weight of the medicinal materials, decoct for 1 hour each time, and decoct at the boiling temperature of the solution. The secondary extracts are combined, filtered, and concentrated under reduced pressure to a concentrated solution with a relative density of 1.04, which is the active ingredient liquid of the present invention.

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PUM

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Abstract

The present invention discloses a traditional Chinese medicine composition for treating insomnia, and the traditional Chinese medicine composition is mainly made from the following parts by weight of raw medicinal materials: 5 to 15 parts of Dactylicapnos scandens, 3 to 10 parts of rhizoma acori graminei and 1 to 5 parts of Ligusticum wallichii. The present invention also discloses preparation methods of a crude drug powder active ingredient liquid and dry extract powder of the traditional Chinese medicine composition. The traditional Chinese medicine composition is simple in prescription, and has the effects of tranquilizing and allaying excitement and promoting blood and qi circulation. Pharmacodynamic study results indicate that the traditional Chinese medicine composition, by intragastric administration, can significantly reduce threshold dose pentobarbital sodium-induced mice sleep latency, prolongs sleep time, and strengthens threshold dose pentobarbital sodium hypnosis effect, can induce sleeping of subthreshold dose pentobarbital sodium-administrated mice, and strengthens subthreshold dose pentobarbital sodium hypnosis effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating insomnia and a preparation method thereof. Background technique [0002] Insomnia refers to the disturbance of the initiation and maintenance of sleep, which makes the quality and quantity of sleep unable to meet the individual's physiological needs, causing patients to feel that they have not fully rested and recovered their energy during the day, resulting in physical fatigue and listlessness. Drowsiness, decreased concentration, difficulty thinking, unresponsiveness, depressed mood, and restlessness. It is probably the most common clinical symptom after pain, and it is more common in women and the elderly. Insomnia is the most common sleep disorder with a high prevalence. In the United States, Australia and some European countries, the prevalence of insomnia is 35.2%. The in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P25/20
Inventor 宋淑芹
Owner 宋淑芹
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