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Traditional Chinese medicine composition for treating atherosclerosis and preparation method thereof

A technology of atherosclerosis and composition, applied in the field of medicine and health

Inactive Publication Date: 2016-05-18
GUANGXI WUZHOU PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, atherosclerosis mainly uses statins and other blood lipid-lowering drugs, but it can cause a variety of side effects, and hyperlipidemia such as atherosclerosis generally requires long-term medication, so it is necessary to develop a mild traditional Chinese medicine that treats both symptoms and root causes preparation

Method used

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  • Traditional Chinese medicine composition for treating atherosclerosis and preparation method thereof
  • Traditional Chinese medicine composition for treating atherosclerosis and preparation method thereof
  • Traditional Chinese medicine composition for treating atherosclerosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] 1) Take 70g of hairy double-face needle, 20g of sheep ear chrysanthemum, 35g of cloves, 70g of lost sticks, 27g of dichotoma root, 70g of dormitica, 20g of jitters, 26g of Guoganglong, 120g of Cyperus rotundus, and 40% ethanol for extraction. 9 times the weight of the medicinal material, heated and extracted twice, 1 hour each time, filtered, the filtrate is concentrated, and adsorbed with pretreated NKA-9 type macroporous resin, the resin column diameter to height ratio is 1:6, and the sample loading speed It is 2BV / h, 40 ethanol elution, elution speed 2BV / h, collect the eluate 4BV, recover the ethanol, obtain the extract, and concentrate it into a liquid extract with a relative density of 1.15 at 60℃;

[0054] 2) Take 50g of Niubai Veng, 40g of false konjac, 30g of Oxtail Vegetable, 60g of Ghost Picture Symbol, 100g of Shanju Leaf, 70g of Liu Jinu, 70g of Shanxiang, 50g of Broken Stone, 80g of Jianzhi, 135g of Black Tiger Root, add 30% acetone to extract , The amount of ...

Embodiment 2

[0057] 1) Take 82g of hairy double-faced needle, 92g of sheep's ear chrysanthemum, 94g of clove, 200g of lost stick, 72g of Dengqiang root, 102g of Dracula vulgaris, 52g of jellyfish, 50g of Guoganglong, 170g of Cyperus rotundus and extract with 80% ethanol. The amount of ethanol is 16 times the weight of the medicinal material, heat extraction 4 times, 4 hours each time, filter, concentrate the filtrate, adsorb with pretreated NKA-9 type macroporous resin, resin column diameter to height ratio of 1:12, sample loading speed 2BV / h, 70% ethanol elution, elution rate 2BV / h, collect the eluate 4BV, recover the ethanol, obtain the extract, and concentrate it into a liquid extract with a relative density of 1.20 at 80°C;

[0058] 2) Take 82g of Niubai Veng, 82g of fake konjac, 82g of oxtail vegetables, 200g of ghost painting symbols, 180g of mountain orange leaf, 110g of Liu Jinu, 128g of mountain incense, 120g of piercing stone, 200g of Jianzhi, 170g of black tiger root, and 60% aceton...

Embodiment 3

[0061] 1) Take 76g of Mao Liangmianzhen, 75g of Lavender chrysanthemum, 55g of cloves, 95g of lost sticks, 57g of Dengqiang root, 89g of Dracula, 42g of jellyfish, 36g of Guoganglong, 153g of Cyperus rotundus, plus 57% ethanol for extraction. 12 times the weight of the medicinal material, heated and extracted 3 times, 2 hours each time, filtered, concentrated the filtrate, adsorbed with pretreated NKA-9 type macroporous resin, the ratio of resin column diameter to height is 1:10, sample loading speed 2BV / h, 60% ethanol elution, elution rate 2BV / h, collect the eluate 4BV, recover the ethanol, obtain the extract, and concentrate it into a liquid extract with a relative density of 1.18 at 70°C;

[0062] 2) Take 67g of Niu Bai Veng, 76g of false konjac, 56g of Oxtail Vegetable, 106g of Ghost Painting Symbol, 110g of Shanju Leaf, 76g of Liu Jinu, 86g of Mountain Fragrant, 76g of Broken Stone, 150g of Jianzhi, 153g of Black Tiger Root, and 340% acetone to extract The amount of acetone ...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating atherosclerosis and a preparation method thereof. The composition is prepared from hedyotidous hedyotis stem and leaf, piper sarmentosum, carrionflower greenbrier, achyranthes root, ichnocarpus oliganthous, fruticose breynia juvenile branchlet and leaf, glycosmis citrifolia leaf, inula cappa, herba artemisiae, climbing entada, wild spikenard, radix cudramiae, zanthoxylum nitidum var. tomentosum, spatholobus stem, common claoxylon root and leaf, atropa belladonna root, heracleum hemsleyanum michaux, pepperbox, fructus gardeniae, clove, nutgrass galingale rhizome and radix kadsurae coccineae as raw materials. The invention also provides a preparation method of the traditional Chinese medicine composition for treating atherosclerosis.

Description

Technical field [0001] The present invention relates to the field of medicine and health, in particular to a traditional Chinese medicine composition for treating atherosclerosis and a preparation method thereof. Background technique [0002] Atherosclerosis is a disease (or pathogenic factor) that mainly affects the large and middle arteries. The basic lesions are lipid deposition in the arterial intima, focal fibrosis of the intima, and atherosclerotic plaque formation that causes the tube wall to become hard and the cavities narrowed, which in turn causes a series of secondary lesions, especially in the heart and brain blood vessels. Causes ischemic disease. With the improvement of living standards, the prevalence and mortality of cardiovascular and cerebrovascular atherosclerotic diseases have continued to increase. [0003] At present, atherosclerosis mainly uses statins and other hypolipidemic drugs, but they can cause a variety of side effects. Hyperlipidemia such as ather...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P9/10
CPCA61K36/896A61K9/1652A61K9/2018A61K9/4866A61K36/185A61K36/21A61K36/232A61K36/28A61K36/282A61K36/46A61K36/47A61K36/48A61K36/486A61K36/54A61K36/57A61K36/60A61K36/61A61K36/67A61K36/74A61K36/744A61K36/758A61K36/79A61K36/81A61K36/8905A61K2236/333A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 黄宇声梁云飞吴赛春林艳英郑志远李柏霖杨北妮
Owner GUANGXI WUZHOU PHARMA GRP
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