Single-cell subnanoscale motion control system based on nanoscale micromanipulation

A motion control system, sub-nano-level technology, applied in control/regulation systems, mechanical control devices, instruments, etc., can solve the rare problems of single-cell motion control systems, and achieve space saving on the stage, wide range, and motion control Sophisticated Effects

Active Publication Date: 2017-02-01
ZHEJIANG PULUOTING HEALTH TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are few formed single-cell motion control systems on the market, especially as sub-modules, single-cell motion control systems that can be easily and conveniently integrated into new systems are even rarer

Method used

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  • Single-cell subnanoscale motion control system based on nanoscale micromanipulation
  • Single-cell subnanoscale motion control system based on nanoscale micromanipulation
  • Single-cell subnanoscale motion control system based on nanoscale micromanipulation

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Embodiment Construction

[0023] The present invention will be further described below in conjunction with drawings and embodiments.

[0024] Such as figure 1 , figure 2 , image 3 As shown, the present invention includes a micromanipulation platform 1, a first adapter plate 2, a single-axis sub-nanometer positioning system 3, a second adapter plate 4, a probe holder fixture 5, a probe holder 6 and a probe 7.

[0025] The micro-operation platform 1 is fixed on the stage of the microscope, the first adapter plate 2 is fixed on the micro-operation platform 1 through screw holes, the back of the single-axis sub-nanometer positioning system 3 is fixed on the surface of the first adapter plate 2, and the second The upper end of the second adapter plate 4 is connected to the side of the single-axis sub-nanometer positioning system 3, the probe holder fixture 5 is fixed in the screw hole at the lower end of the second adapter plate 4, and the probe holder 6 is stuck in the probe holder In the spring slot...

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Abstract

Disclosed in the invention is a nanometer-level-microoperation-based unicellular sub-nanometer-level motion control system. A microoperation platform is fixed on an objective table of a microscope; a first switching board is fixed on the microoperation platform; and a single-shaft sub-nanometer-level positioning system is fixed on the surface of the first switching board. An upper end of a second switching board is connected to the side surface of the single-shaft sub-nanometer-level positioning system; a probe clamping device clamp is fixed at a lower end of the second switching board; and a probe clamp with a probe installed at the front end is clamped in a spring clamp groove of the probe clamping device clamp. The probe arranged at the front end of the probe clamp is processed by opening according to the design demand; and cells near the pointed end of the probe are absorbed or released based on a positive pressure or negative pressure provided by the rear end of the probe clamp. According to the invention, the three-shaft precision can reach 7nm, the control range can be to 20nm, and the damages on living cells are low; the motion control precision is high and the closed ring precision can reach 0.05 nm; and because of the small three-dimensional size of the microoperation platform, the space of the objective table is saved and integration of the table to other complicated experiment systems can be realized easily.

Description

technical field [0001] The invention relates to a single-cell motion control system, in particular to a single-cell sub-nanometer motion control system based on nanoscale micromanipulation. Background technique [0002] The combination of engineering and biomedicine can solve many problems that cannot be solved by traditional biological methods. It is an important way to combine engineering and biomedicine to apply the methods of research problems in the field of engineering to the research of biology. With the development of biophysical methods in recent years, many novel and efficient methods have gradually become important tools in biomedical research. There are often no integrated products in the market for these emerging systems, but users can skillfully integrate the formed sub-modules into the new system according to their needs. [0003] The control of cell movement is the basis of many research methods in the field of biomechanics, but the complete precise control ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G05G21/00
CPCG05G21/00
Inventor 陈伟安宸毅
Owner ZHEJIANG PULUOTING HEALTH TECH CO LTD
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