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Chinese and western integrated medicine composition treating diaper dermatitis of new born children, and preparation method of Chinese and western integrated medicine composition

A diaper dermatitis technology combining Chinese and Western technologies, applied in drug combination, drug delivery, medical formula, etc., can solve the problems of being easily penetrated by foreign objects, redness, swelling and ulceration, and weak skin resistance, so as to relieve discomfort and avoid diseases , reduce the effect of crying

Inactive Publication Date: 2016-06-01
QILU CHILDRENS HOSPITAL OF SHANDONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Compared with adult skin, newborn skin has the following characteristics: 1. The ratio of skin area to body weight is much larger than that of adults, and the reaction to allergic substances or toxic substances is much stronger; 2. The skin epidermis of newborns It is a single layer of cells, while adults have multiple layers of cells. The dermis of newborn skin has fewer collagen fibers, so it lacks elasticity, is easily penetrated by foreign objects and is easily damaged by friction, especially in the folds, which are more likely to be damaged by friction. 3. Because newborns only rely on a layer of natural acid protective film on the skin surface to protect the skin, the skin has poor ability to control acid and alkali, and is extremely vulnerable to bacterial invasion, resulting in local redness and swelling Ulceration; 4. Newborns have very little melanin in their skin, so their skin pigmentation is thin, and they are easily burned by ultraviolet rays in the sun, forming ulceration; 5. Because the sweat glands and blood vessels of newborns are still developing, resulting Its skin temperature regulation ability is weak, and when the ambient temperature rises, it is easy to produce heat prickly heat, accompanied by itching, and newborns instinctively scratch, which can easily lead to ulceration; , leading to weaker skin resistance, more prone to skin allergies, such as erythema, papules, blisters, etc., and the blisters are easy to rupture

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1 ointment

[0030] The Chinese and Western medicinal ointment for the treatment of neonatal diaper dermatitis described in this embodiment, its raw material composition comprises: comfrey 20g, Phellodendron 30g, Sophora flavescens 10g, Borneolum 15g, Artemisia argyi 5g, Fructus Cnidii 20g, erythromycin ointment 5g, Vitamin C0.3g.

[0031] The preparation method of the Chinese and Western medicinal ointment for the treatment of neonatal diaper dermatitis described in this embodiment comprises the following steps:

[0032] (1) Take a selected amount of comfrey, phellodendron, flavescens, borneol, mugwort leaves, cnidium and vitamin C, mix them and grind them into granules with a particle size of less than 10um;

[0033] (2) Take a selected amount of erythromycin ointment and mix with the above-mentioned granules, and add conventional excipients according to a conventional process to make a clinically acceptable ointment.

Embodiment 2

[0034] Embodiment 2 gel

[0035] The combination of Chinese and Western medicine gel for treating neonatal diaper dermatitis described in this embodiment, its raw material composition includes: Comfrey 40g, Cortex Phellodendri 10g, Sophora flavescens 20g, Borneolum 5g, Artemisia argyi 15g, Fructus Cnidii 10g, erythromycin ointment 15g , vitamin C0.1g.

[0036] The preparation method of the Chinese and Western medicinal gel for treating neonatal diaper dermatitis described in this embodiment comprises the following steps:

[0037] (1) Take a selected amount of comfrey, phellodendron, flavescens, borneol, mugwort leaves, cnidium and vitamin C, mix them and grind them into granules with a particle size of less than 10um;

[0038] (2) Take a selected amount of erythromycin ointment and mix with the above-mentioned granules, and add conventional excipients according to the conventional process to make a clinically acceptable gel.

Embodiment 3

[0039] Embodiment 3 ointment

[0040] The Chinese and Western medicine ointment for the treatment of neonatal diaper dermatitis described in the present embodiment, its crude drug composition comprises: comfrey 30g, Phellodendron 20g, Sophora flavescens 15g, Borneolum 10g, Folium Artemisiae Argyi 10g, Fructus Cnidii 15g, erythromycin ointment 10g, Vitamin C0.2g.

[0041] The preparation method of the Chinese and Western medicine ointment for treating neonatal diaper dermatitis described in this example is the same as that in Example 1.

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PUM

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Abstract

The invention belongs to the technical field of Chinese herbal preparation, particularly relates to a Chinese and western integrated medicine composition treating diaper dermatitis of new born children, and further discloses a preparation method of the Chinese and western integrated medicine composition. The Chinese and western integrated medicine composition adopts the treating concept of Chinese and western integration, and adopts lithospermum, cortex phellodendri, radix sophorae flavescentis, borneol, folium artemisiae argyi, fructus cnidii, vitamin C and erythromycin ointment as active pharmaceutical ingredients; the integral effective rate of the Chinese and western integrated medicine composition reaches up to 100 percent in the aspect of treating diaper dermatitis; the Chinese and western integrated medicine composition is not only obvious in treating effect, and free of side effects, but also relatively short in treating circle, thereby being obviously better than conventional treatment in the prior art.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a Chinese and Western medicinal composition for treating neonatal diaper dermatitis, and further discloses a preparation method thereof. Background technique [0002] Newborns are a veritable special group in society, especially premature babies are a vulnerable group among this vulnerable group. The vitality of premature babies is extremely fragile, and the development of various organs is immature, which may easily lead to functional disorders of various organs. The skin is the largest organ of the human body, not only extremely delicate; moreover, the condition of the newborn's skin can directly affect the treatment effect and quality of life of premature infants. [0003] Compared with adult skin, newborn skin has the following characteristics: 1. The ratio of skin area to body weight is much larger than that of adults, and the re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P17/00A61K31/045A61K31/375A61K31/7048
CPCA61K36/30A61K9/0014A61K9/06A61K31/045A61K31/375A61K31/7048A61K36/234A61K36/282A61K36/489A61K36/756A61K2300/00
Inventor 李晓梅庄元华郎玉洁韩玉杰刘晨许群
Owner QILU CHILDRENS HOSPITAL OF SHANDONG UNIV
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