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Kits that can be used to aid in the diagnosis of malaria

A kit, malaria technology, applied in biological testing, resistance to vector-borne diseases, material testing products, etc., can solve problems such as limiting the rapid and effective diagnosis of malaria

Active Publication Date: 2018-04-24
SUZHOU INST OF NANO TECH & NANO BIONICS CHINESE ACEDEMY OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These factors limit the clinical rapid and effective diagnosis of malaria

Method used

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  • Kits that can be used to aid in the diagnosis of malaria

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0123] 1. Preparation and Confirmation of Peptides

[0124] The polypeptides used in the examples were synthesized by Jill Biochemical (Shanghai) Co., Ltd. and confirmed by mass spectrometry. in,

[0125] SEQ ID NO: 1: (SEIILPENVETEEIIDDVPSPKHSNHETFE); molecular weight 3449.

[0126] SEQ ID NO: 2: (NDFSEYHEDINDINFKK); molecular weight 2128.

[0127] SEQ ID NO: 3: (GESKETGESKETGESKETGESKETGESKET); molecular weight 3176.

[0128] SEQ ID NO: 4: (AGKKIDKKKEQANKKNNNNNKNKNKNKNKNLSK); molecular weight is (3468).

[0129] SEQ ID NO: 5: (IVPEQNDEESGESGLVDNEEGDFEEPNHEE); molecular weight 3373.

[0130] SEQ ID NO: 6: (EIKKQVEEGIKEENDTEGNDKVKGPEIITEE); molecular weight (3400).

[0131] SEQ ID NO: 7: (SFWGEEKRASHTTPVLMEKPYY); molecular weight 2657.

[0132] SEQ ID NO: 8: (AEKPYIIPTSNCSANDIVKYEHTLKTQITL); molecular weight 3392.

[0133] SEQ ID NO: 9: (KNDEQKDKVLGEGDKEDVKEKNDEQKDKVL); molecular weight 3502.

[0134] 2. Preparation of detection kit

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Abstract

The invention relates to a reagent kit and a diagnostic method thereof which can be used for auxiliary diagnosis of malaria. The kit of the present invention includes one or more solid supports, and a specific set of polypeptides independently linked to the one or more solid supports. The product of the invention can be used for auxiliary detection of malaria, especially Plasmodium falciparum infection.

Description

technical field [0001] The present invention mainly relates to kits and diagnostic methods. In particular, the present invention relates to diagnostic kits for the detection of malaria infection, in particular for the detection of Plasmodium falciparum infection. Background technique [0002] Malaria remains a critical issue of global public health, with an annual death toll of 0.7-2.7 million, of which more than 75% are African children. In the past 35 years, the incidence of malaria has increased by 2-3 times. In 1955, the World Health Organization (WHO) embarked on an ambitious program to eradicate malaria through the clinical application of chloroquine and the application of DDT (dichlorodiphenyltrichloroethane) to control mosquito populations. Phased out in the late 1960s, this program has led to significant and sustained reductions in disease burden in many countries around the world. However, malaria relapses persist in many countries, mainly due to the emergence a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/68G01N33/569C07K14/445
CPCY02A50/30
Inventor 马宏伟卢煜东刘星李钟徐宏科陈文凤黄沫马青茶文丽刘岑
Owner SUZHOU INST OF NANO TECH & NANO BIONICS CHINESE ACEDEMY OF SCI
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