Traditional Chinese medicinal composition for treating primary hypertension and preparation method of traditional Chinese medicinal composition

A technology of essential hypertension and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of slow onset of effect and insignificant effect, achieve rapid onset of effect and reduce adverse effects Response, drug effect, comprehensive effect

Inactive Publication Date: 2016-07-20
GUANGDONG JUZHICHENG TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Antihypertensive drugs need long-term or life-long application, drug safety and patient tolerance are very important, traditional Chinese medicine treatment of high blood pressure drugs have few side effects and stable drug effect, can be used safely for a long time, and have broad prospects, but existing prevention and treatment of high blood pressure The existing traditional Chinese medicine has insignificant effect, slow onset and other deficiencies. It is of great significance for the clinical treatment of essential hypertension to seek a Chinese medicine composition with remarkable effect, fast onset and convenient taking.

Method used

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  • Traditional Chinese medicinal composition for treating primary hypertension and preparation method of traditional Chinese medicinal composition

Examples

Experimental program
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Effect test

Embodiment 1

[0032] The traditional Chinese medicine composition of Example 1 of the present invention is mainly prepared from the following raw materials in parts by weight:

[0033] Purslane 12 parts, Apocynum 14 parts, Stinky Indus 16 parts, Yunnan Changshan 12 parts, capillary 10 parts, Uncaria 14 parts, Chuanxiong 12 parts, jujube 6 parts, dendrobium 4 parts, yam 10 parts, hawthorn 6 parts 4 parts and licorice.

[0034] The preparation method is as follows:

[0035]S1: Take purslane, wash away impurities, dry and pulverize, pass through a 60-mesh sieve, add ethanol with a volume fraction of 60% in an amount 8 times the weight of purslane, and extract by microwave for 8 minutes, the microwave power is 240W, and the extraction temperature is 40 ℃, filter and retain the purslane medicinal residue, and concentrate the filtrate under reduced pressure to an extract whose relative density is 1.20 at 60 ℃ to obtain the purslane extract;

[0036] S2: Take apocynum, sycamore, Yunnan Changshan...

Embodiment 2

[0042] The Chinese medicine composition of Example 2 of the present invention is mainly prepared from the following raw materials in parts by weight:

[0043] 28 parts of purslane, 30 parts of apocynum, 24 parts of stinky phoenix tree, 18 parts of Yunnan Changshan, 18 parts of capillary, 24 parts of Uncaria, 20 parts of Chuanxiong, 10 parts of jujube, 12 parts of dendrobium, 16 parts of yam, 10 parts of hawthorn 12 parts and 12 parts of licorice.

[0044] The preparation method is the same as in Example 1.

Embodiment 3

[0046] The Chinese medicine composition of Example 3 of the present invention is mainly prepared from the following raw materials in parts by weight:

[0047] 20 parts of purslane, 22 parts of apocynum, 20 parts of stinky phoenix tree, 16 parts of Yunnan Changshan, 14 parts of capillary, 18 parts of Uncaria, 16 parts of Chuanxiong, 8 parts of jujube, 8 parts of dendrobium, 14 parts of yam, and 8 parts of hawthorn 6 parts and licorice.

[0048] The preparation method is as follows:

[0049] S1: Take purslane, wash away impurities, dry and pulverize, pass through a 80-mesh sieve, add ethanol with a volume fraction of 80% in an amount 10 times the weight of purslane, extract with microwave for 15 minutes, microwave power is 300W, and extraction temperature is 60 ℃, filter and retain the purslane dregs, concentrate the filtrate under reduced pressure to 60 ℃ to measure the extract with a relative density of 1.25, and obtain the purslane extract;

[0050] S2: Take apocynum, sycam...

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Abstract

The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicinal composition for treating primary hypertension. The traditional Chinese medicinal composition is mainly prepared from the following raw materials in parts by weight: 12-28 parts of herba portulacae, 14-30 parts of folium apocyni veneti, 16-24 parts of harlequin glorybower leaf and twig, 12-18 parts of Yunnan glorybower, 10-18 parts of herba artemisiae capillariae, 14-24 parts of ramulus uncariae cum uncis, 12-20 parts of rhizoma ligusticum wallichii, 6-10 parts of fructus ziziphi jujubae, 4-12 parts of herba dendrobii, 10-16 parts of dioscoreae rhizoma, 6-10 parts of fructus crataegi and 4-12 parts of liquorice root. The traditional Chinese medicinal composition disclosed by the invention is reasonable in medicine prescription and strong in synergistic effect; and the traditional Chinese medicinal composition, on treating the primary hypertension, is significant in curative effect, stable in efficacy, low in side effects of medicines and obvious in clinical popularization value.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating essential hypertension and a preparation method thereof. Background technique [0002] According to the WHO standard, the normal blood pressure of the human body is systolic blood pressure 140mmHg and (or) diastolic blood pressure 90mmHg, beyond this range can be diagnosed as hypertension. Hypertension is a common cardiovascular disease, which is defined as a persistent increase in systemic arterial pressure. Hypertension secondary to kidney, endocrine and nervous system diseases is called secondary hypertension, accounting for 5% to 10% of hypertensive patients; and hypertension whose cause has not been clarified so far is called primary hypertension. hypertension. Essential hypertension accounts for more than 90% of hypertensive patients, and is often accompanied by disorders of fat and glucose met...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P9/12
CPCA61K36/185A61K36/236A61K36/24A61K36/282A61K36/484A61K36/725A61K36/734A61K36/74A61K36/855A61K36/8945A61K36/8984A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53
Inventor 邓凤桂
Owner GUANGDONG JUZHICHENG TECH
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