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Traditional Chinese medicine extractive composition and preparation method thereof

A technology of extracts and compositions, applied in the field of traditional Chinese medicine extract compositions and their preparation, can solve the problems of etiological treatment, poor curative effect, large side effects, etc., achieve good therapeutic effect, no drug resistance, and significant curative effect

Inactive Publication Date: 2016-07-27
SHAANXI INST OF INT TRADE & COMMERCE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] It can be seen that although there are many antitussive drugs sold on the market, they have the disadvantages of large side effects, poor effect and easy recurrence of the disease after drug withdrawal.
These cough medicines can only relieve the condition temporarily, and do not really treat the cause, so the curative effect is not good

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] S1, the preparation of ivy extract:

[0044] S11. After the aqueous solution of the dried ivy leaves is crushed through an ultrafiltration membrane for membrane separation, the permeate is collected and concentrated to 10% of the original volume to obtain a concentrated solution;

[0045] S12. Pass the obtained concentrated solution through the macroporous resin column at a flow rate of 3BV / h. After the dynamic adsorption is saturated, rinse the above-mentioned macroporous resin column with deionized water at a flow rate of 5BV / h until the effluent is colorless, and then use volume The organic solvent with a fraction of 50% was eluted at a flow rate of 8BV / h, and the eluate was collected and concentrated under reduced pressure to obtain an extract;

[0046] S13. Dissolve the extract in water and pass through the polyamide column at a flow rate of 3BV / h. After the dynamic adsorption is saturated, rinse the above-mentioned polyamide column with 3BV deionized water at a fl...

Embodiment 2

[0066] S1, the preparation of ivy extract:

[0067] S11. After the aqueous solution of the dried ivy leaves is crushed through an ultrafiltration membrane for membrane separation, the permeate is collected and concentrated to 10% of the original volume to obtain a concentrated solution;

[0068] S12. Pass the obtained concentrated solution through the macroporous resin column at a flow rate of 7BV / h. After the dynamic adsorption is saturated, rinse the above-mentioned macroporous resin column with deionized water at a flow rate of 8BV / h until the effluent is colorless, and then use volume The organic solvent with a fraction of 70% was eluted at a flow rate of 12BV / h, and the eluate was collected and concentrated under reduced pressure to obtain an extract;

[0069] S13. Dissolve the extract in water and pass through the polyamide column at a flow rate of 5BV / h. After the dynamic adsorption is saturated, rinse the above-mentioned polyamide column with 7BV deionized water at a f...

Embodiment 3

[0089] S1, the preparation of ivy extract:

[0090] S11. After the aqueous solution of the dried ivy leaves is crushed through an ultrafiltration membrane for membrane separation, the permeate is collected and concentrated to 10% of the original volume to obtain a concentrated solution;

[0091] S12, pass the obtained concentrated solution through the macroporous resin column at a flow rate of 5BV / h, after the dynamic adsorption is saturated, rinse the above-mentioned macroporous resin column with deionized water at a flow rate of 6.5BV / h until the effluent is colorless, and then use The organic solvent with a volume fraction of 60% was eluted at a flow rate of 15BV / h, and the eluate was collected and concentrated under reduced pressure to obtain an extract;

[0092] S13. Dissolve the extract in water and pass through the polyamide column at a flow rate of 4BV / h. After the dynamic adsorption is saturated, rinse the above-mentioned polyamide column with 5BV deionized water at a...

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Abstract

The invention discloses a traditional Chinese medicine extractive composition and a preparation method thereof, wherein the extractive composition is prepared from the following components: by weight, 42-62 parts of hedera helix extractive, 5-10 parts of Marian thistle extractive, 3-5 parts of olive leaf extractive, 6-12 parts of fennel extractive, 10-15 parts of liquorice extractive, 10-15 parts of radix ophiopogonis extractive, 10-15 parts of dried tangerine peel extractive, and 8-10 parts of radix polygonati officinalis. By a special technology, the hedera helix extractive, Marian thistle extractive, olive leaf extractive, fennel extractive, liquorice extractive, radix ophiopogonis extractive, dried tangerine peel extractive and radix polygonati officinalis of higher purities are obtained and combined by an optimal proportion. The composition has a good curative effect on cough; it is safe and nontoxic with remarkable curative effect, and without generating resistance to drugs; it clinical effective rate is up to 97%, and its cure rate is up to 92%.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extraction mixture, in particular to a traditional Chinese medicine extract composition and a preparation method thereof. Background technique [0002] Coughing is a protective breathing reflex action of the human body, which can effectively remove secretions in the respiratory tract or foreign objects entering the airway. However, under pathological conditions, such as long-term, frequent and severe cough, it seriously affects the daily life of the patient. [0003] Coughing in a pathological state can lead to respiratory bleeding and even cause symptoms such as sore throat, hoarseness, and respiratory myalgia. In traditional Chinese medicine, cough refers to a disease characterized by coughing or phlegm due to factors such as exogenous pathogenic factors or internal injuries that cause the lungs to lose their ventilation and depletion, and the lung qi goes up against the airway and impacts the ...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P11/14
CPCA61K36/25A61K36/23A61K36/28A61K36/32A61K36/484A61K36/752A61K36/8968A61K36/8969A61K2236/19A61K2236/331A61K2236/333A61K2236/35A61K2236/37A61K2236/39A61K2236/55A61K2300/00
Inventor 王燕唐静王飞娟张爽高洁王青豆佳媛赖普辉
Owner SHAANXI INST OF INT TRADE & COMMERCE
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