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A kind of pharmaceutical composition and application of optic nerve protection

A protective effect and composition technology, applied in drug combinations, nervous system diseases, pharmaceutical formulations, etc., can solve the problems of unclear mechanism of optic nerve injury treatment intervention and insufficient research, so as to improve optic nerve injury and promote heat shock Complex effects on protein expression, pathogenesis

Active Publication Date: 2020-11-24
HUNAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the research on the protective effect of traditional Chinese medicine on glaucoma visual function has made great progress, but at the same time, the mechanism of treatment intervention for optic nerve injury is not clear enough, and the research is not deep enough.

Method used

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  • A kind of pharmaceutical composition and application of optic nerve protection
  • A kind of pharmaceutical composition and application of optic nerve protection
  • A kind of pharmaceutical composition and application of optic nerve protection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A medicinal composition for optic nerve protection, which is prepared from the following components: 15g wolfberry, 10g chuanxiong, 10g escutellaria, 15g astragalus, 15g ligustrum lucidum and 10g achyranthes bidentata.

Embodiment 2

[0041] A medicinal composition for optic nerve protection, which is prepared from the following components: 12g wolfberry, 8g chuanxiong, 9g escutellaria, 11g astragalus, 12g ligustrum lucidum and 8g achyranthes bidentata.

Embodiment 3

[0043] A pharmaceutical composition with protective effect on optic nerve, which is prepared from the following components: 20g of wolfberry, 12g of chuanxiong, 12g of scutellaria, 19g of astragalus, 18g of privet fruit and 12g of achyranthes bidentata.

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PUM

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Abstract

The invention relates to a medicinal composition with an optic nerve protection effect and application. The medicinal composition is prepared from the following raw materials in parts by weight: 10 to 20 parts of Chinese wolfberries, 8 to 12 parts of ligusticum wallichii, 8 to 12 parts of erigeron breviscapus, 10 to 20 parts of astragalus membranaceus, 10 to 20 parts of fructus ligustri lucidi and 8 to 12 parts of achyranthes bidentata. According to the theory of traditional Chinese medicine, main pathogenesis of optic nerve damage caused by chronic ocular hypertension is liver-kidney deficiency, aqueous humor and tear deposition, qi-blood disharmony, vein obstruction and blockage of sweat pores in eyes, and the medicinal composition is provided on the basis of treatment methods of nourishing liver and kidney, tonifying qi and activating blood circulation, and has good curative effects on optic nerve damage caused by chronic ocular hypertension.

Description

technical field [0001] The present invention relates to the technical field of traditional Chinese medicines, in particular to a pharmaceutical composition and its application for optic nerve protection, in particular to a pharmaceutical composition for treating / preventing / relieving optic nerve damage. Background technique [0002] At present, the methods used to protect optic nerve damage include drug therapy, gene therapy, stem cell transplantation, and retinal transplantation, etc., and they work on different links of glaucoma optic nerve damage through different principles and mechanisms. Drugs are still the most basic and common clinical treatment. The drugs used to promote the repair of optic nerve damage mainly include the following: ①Calcium channel blockers: Elevated intraocular pressure causes more calcium ions to flow into cells from the outside Inside, at this time retinal cell Ca 2+ overload, resulting in retinal damage. Calcium channel blockers inhibit Ca 2+...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/815A61P25/00A61P27/02
CPCA61K36/21A61K36/236A61K36/28A61K36/481A61K36/638A61K36/815A61K2236/331A61K2236/39A61K2300/00
Inventor 彭清华彭俊谭涵宇周亚莎
Owner HUNAN UNIV OF CHINESE MEDICINE