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Traditional Chinese medicinal injection for treating ischemic stroke with syndromes of stagnation and obstruction of heat-toxin and blood stasis

A technology of blood stasis type and cerebral ischemia, which is applied in the field of traditional Chinese medicine to achieve the effect of improving the quality of prognosis, saving lives and taking immediate effect.

Inactive Publication Date: 2016-08-24
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, it is a new point of view to protect cerebral ischemia by promoting blood circulation, removing blood stasis and clearing away heat and detoxification. Previously, there were few literature reports on this aspect, but there are feasible pretreatment measures for clinical application. provide new methods

Method used

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  • Traditional Chinese medicinal injection for treating ischemic stroke with syndromes of stagnation and obstruction of heat-toxin and blood stasis
  • Traditional Chinese medicinal injection for treating ischemic stroke with syndromes of stagnation and obstruction of heat-toxin and blood stasis
  • Traditional Chinese medicinal injection for treating ischemic stroke with syndromes of stagnation and obstruction of heat-toxin and blood stasis

Examples

Experimental program
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Effect test

preparation example Construction

[0064] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine injection, which includes:

[0065] The first step is to take salvia miltiorrhiza, angelica, red peony root, breviscapine, leech, earthworm, scorpion, turmeric, holly, trumpet creeper, persimmon leaf, forsythia, bezoar powder, artificial bear bile, borneol, peony bark, and fungus Chen, Andrographis paniculata, wild chrysanthemum, honeysuckle, hawthorn, raw rhubarb and aloe, the effective ingredients are extracted with ethanol;

[0066] The second step is to take the remaining API components by weight, add the dregs obtained after extracting the active ingredients in the first step, add water to extract 2 to 3 times, each time adding water to each API weighed in this step and the first step to obtain 3 to 4 times the sum of the mass of the dregs, combine the extracts, filter, refrigerate for 24 to 72 hours, filter, add the ethanol obtained in the first step to the filt...

Embodiment 1

[0069] Example 1 Injection 1

[0070] Take 30g Salvia miltiorrhiza, Angelica 20g, Red peony root 15g, Dengzhanxixin 10g, Leech 5g, Dilong 10g, Scorpion 5g, Turmeric 20g, Ilex glabra 10g, Campsis flower 20g, Persimmon leaf 15g, Forsythia 15g, Bezoar powder 10g, artificial 10g of bear bile, 15g of borneol, 15g of tree peony, 10g of cylindrica, 15g of Andrographis paniculata, 30g of wild chrysanthemum, 30g of honeysuckle, 15g of hawthorn, 25g of rhubarb, and 20g of aloe vera. Ethanol, heated and refluxed for 2 times, 4 hours each time, the extracts were combined and concentrated to remove the ethanol to obtain a dry paste, crushed into powder, and the filter residue for later use. Take 30g of Ligusticum chuanxiong, 25g of Panax notoginseng, 15g of Achyranthes bidentata and 20g of turmeric , Safflower 10g, Peach kernel 15g, Indigo Naturalis 30g, Acorus calamus 15g, Polygonum cuspidatum 20g, Musk 10g, Coptis 20g, Pueraria lobata 15g, Gardenia 30g, add the dregs obtained after extracti...

Embodiment 2

[0071] Example 2 Injection 2

[0072] Take Salvia miltiorrhiza 30g, Angelica 15g, Red Peony root 15g, Dengzhanxixin 10g, Leech 5g, Dilong 10g, Scorpion 5g, Turmeric 15g, Ilex glabra 10g, Crassopsis 15g, Persimmon leaves 10g, Forsythia 15g, Bezoar powder 10g, artificial 10g of bear bile, 10g of borneol, 15g of Cortex Moutan, 10g of Cymbidium, 15g of Andrographis paniculata, 30g of wild chrysanthemum, 30g of honeysuckle, 15g of hawthorn, 25g of raw rhubarb, and 20g of aloe vera. Ethanol, heated and refluxed for 2 times, 4 hours each time, the extracts were combined and concentrated to remove the ethanol to obtain a dry paste, crushed into powder, and the filter residue for later use. Take 25g of Ligusticum chuanxiong, 20g of Panax notoginseng, 15g of Achyranthes bidentata and 15g of turmeric , Safflower 10g, Peach kernel 15g, Indigo Naturalis 30g, Acorus calamus 15g, Polygonum cuspidatum 20g, Musk 10g, Coptis 20g, Pueraria lobata 15g, Gardenia 25g, add the dregs obtained after extr...

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Abstract

The invention provides a traditional Chinese medicinal injection for treating ischemic stroke with syndromes of stagnation and obstruction of heat-toxin and blood stasis. The injection consists of the following medicinal raw materials: radix salviae miltiorrhizae, radix angelicae sinensis, rhizoma ligustici wallichii, radix paeoniae rubra, radix notoginseng, herba erigeromtis, radix cyathulae, hirudo, lumbricus, scorpio, radix curcumae, flos carthami, peach kernel, radix curcumae longae, radix ilicis pubescentis, flos campsis, persimmon leaves, indigo naturalis, rhizoma acori graminei, fructus forsythiae, giant knotweed rhizome, bezoar powder, artificial bear gall, borneol, musk, radix coptis, radix puerariae, fructus gardeniae, cortex moutan, herba artemisiae capillariae, herba andrographitis, flos chrysanthemi indici, honeysuckle flowers, fructus crataegi, radix et rhizoma rhei and aloe. The injection can directly penetrate into blood and reach a whole body, so as to take effects more rapidly and more directly, and to rapidly improve the blood supply of a focus with cerebral ischemia; therefore, the injection can rescue patient's life and improve prognosis quality of a patient; and based upon experimental researches, clinical researches and safety assessment on the injection, the traditional Chinese medicinal injection disclosed by the invention is suitable for clinical popularization and application.

Description

Technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine injection for treating cerebral ischemic stroke of heat toxin and blood stasis type. Background technique [0002] Traditional Chinese medicine believes that the occurrence of ischemic stroke is mainly related to wind and fire, phlegm, blood stasis, qi deficiency, heat toxin and other factors. Blood stasis and heat toxin are important influencing factors, and blood stasis is most closely related. Therefore, it is advocated to use "activating blood to remove blood stasis" to improve microcirculation to treat this disease. In recent years, with the deepening of the understanding of traditional toxins, the development of stroke clinical practice and the in-depth study of modern pathological mechanisms, it has been proposed to treat stroke from the theory of toxicity, thereby improving the curative effect of stroke, and has become a rese...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/08A61P9/10A61K35/646A61K35/62A61K35/55A61K35/413A61K31/045
CPCA61K36/9066A61K9/0019A61K9/08A61K31/045A61K35/413A61K35/55A61K35/62A61K35/646A61K36/185A61K36/19A61K36/195A61K36/21A61K36/232A61K36/236A61K36/258A61K36/28A61K36/286A61K36/287A61K36/315A61K36/355A61K36/44A61K36/488A61K36/537A61K36/634A61K36/65A61K36/704A61K36/708A61K36/71A61K36/718A61K36/734A61K36/736A61K36/744A61K36/886A61K36/888A61K36/896A61K47/26A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 王兰英
Owner QINGDAO MUNICIPAL HOSPITAL
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