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A kind of compound mature vinegar microcapsule and its preparation method and application

A compound and microcapsule technology, which is applied in the field of compound mature vinegar microcapsules and its preparation, can solve the problem that the oxidative stress level of liver cells has no definite effect, and achieve the effect of enhancing free radical scavenging ability, smooth surface and uniform microcapsule particles

Active Publication Date: 2019-07-05
TIANJIN UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

but had no definite effect on the level of oxidative stress in injured hepatocytes

Method used

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  • A kind of compound mature vinegar microcapsule and its preparation method and application
  • A kind of compound mature vinegar microcapsule and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A preparation method of compound mature vinegar microcapsules, the method comprising the steps of:

[0024] 1. Preparation of concentrated mature vinegar: take Shanxi mature vinegar, concentrate and extract it under vacuum at 35°C, and wait until the concentration of the concentrated mature vinegar reaches 45°Bé; it can be used for later use;

[0025] 2. Preparation of traditional Chinese medicine extracts: respectively pulverize Schisandra chinensis, Astragalus membranaceus, and Glycyrrhiza radibilis to a particle size of 5mm, then add 75% ethanol to each pulverized medicinal powder for extraction three times, each time for 40min, ultrasonic extraction with ultrasonic power of 100W, ultrasonic extraction The frequency of ultrasonic extraction is 30kHz, and then the ethanol is recovered by filtration and concentrated to a thick paste with a relative density of 1.20-1.30 for later use.

[0026] 3. Prepare the mixed solution of microcapsules and cores: take 50 parts of co...

Embodiment 2

[0030] A preparation method of compound mature vinegar microcapsules, the method comprising the steps of:

[0031] 1. Preparation of concentrated mature vinegar: take Shanxi mature vinegar, concentrate and extract it under vacuum at 40°C, and wait until the concentration of concentrated mature vinegar reaches 40°Bé; it can be used for later use;

[0032] 2. Preparation of traditional Chinese medicine extracts: respectively pulverize Schisandra chinensis, Astragalus membranaceus and Glycyrrhiza licorice, and the pulverized particle size is 10mm, and then add 75% ethanol to each pulverized medicinal powder for leaching three times, each time for 50min, ultrasonic leaching, ultrasonic power is 120W, ultrasonic The ultrasonic frequency of extraction is 40kHz, and then the ethanol is recovered by filtration and concentrated to a thick paste with a relative density of 1.20-1.30 for subsequent use;

[0033] 3. Preparation of microcapsule capsule core mixture: take 55 parts of concent...

Embodiment 3

[0037] A preparation method of compound mature vinegar microcapsules, the method comprising the steps of:

[0038] 1. Preparation of concentrated mature vinegar: take Shanxi mature vinegar, concentrate and extract it under vacuum at 45°C, and wait until the concentration of concentrated mature vinegar reaches 50°Bé; it can be used for later use;

[0039] 2. Preparation of traditional Chinese medicine extracts: respectively pulverize Schisandra chinensis, Radix Astragali, and Glycyrrhizae chinensis, and the particle size of the pulverization is 8 mm. After that, add 75% ethanol to each pulverized medicinal powder for extraction three times, each time for 60 min. Ultrasonic extraction. The extraction ultrasonic frequency is 50kHz, and then the ethanol is recovered by filtration and concentrated to a thick paste with a relative density of 1.20-1.30 for subsequent use;

[0040] 3. Prepare the mixed solution of microcapsules and cores: take 60 parts of concentrated mature vinegar, ...

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Abstract

The invention provides compound mature vinegar micro-capsules as well as a preparation method and an application thereof. The compound mature vinegar micro-capsules comprise the following two parts: capsule cores and capsule walls; the capsule cores are prepared from the following raw materials: concentrated mature vinegar, a Chinese magnoliavine fruit extract, a astragalus root extract and a liquorice root extract; and the micro-capsules are prepared by the following steps: embedding the capsule cores in the capsule walls, and carrying out spray-drying. The antioxidant components of the concentrated mature vinegar and the traditional Chinese medicine extracts synergistically react, so that the micro-capsules have stronger free radical scavenging activities and better liver-protecting and health-caring functions. The micro-capsule technology is utilized, so that the antioxidant components therein are better protected so as to prevent oxidation and enhance stability; the micro-encapsulation ensures better dispersibility and sustained release of the active ingredients, so that the active ingredients can effectively and lastingly enter the sites of action to play the liver-protecting and health-caring roles; moreover, the micro-encapsulation shields strong smells of the edible vinegar and the traditional Chinese medicines, so that the color, the luster and the taste of the final products are improved.

Description

technical field [0001] The invention relates to the technical field of health food, in particular to a compound aged vinegar microcapsule and its preparation method and application. Background technique [0002] Acute and chronic liver diseases caused by different causes, such as viral hepatitis, drug-induced liver disease, non-alcoholic steatohepatitis, autoimmune liver disease, etc., can all cause damage to liver cells. Liver cell injury is the common pathological basis of liver disease. Oxidative stress is an important injury mechanism in hepatocellular injury in various liver diseases. Increased levels of oxidative stress can damage cells and even cause cell death, eventually leading to the occurrence and development of diseases such as inflammation and cancer. Therefore, how to reduce the oxidative stress level of liver cells caused by different incentives and reduce the damage to liver cells is of great significance to the protection of the liver. The current hepato...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/50A23L33/00A23L33/105C12J1/00A23P10/30A61K36/79A61K36/57A61P1/16A61P39/06
CPCA23V2002/00A61K9/5036A61K31/19A61K36/481A61K36/484A61K36/57A61K36/79C12J1/00A23V2200/30A23V2250/21A61K2300/00
Inventor 王敏夏婷姚佳慧张祥龙郑宇宋佳
Owner TIANJIN UNIV OF SCI & TECH
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