Traditional Chinese medicine composition capable of diminishing inflammation and easing pain and preparation method thereof

An anti-inflammatory and analgesic composition technology, which is applied in the direction of drug combination, pharmaceutical formula, antipyretic, etc., can solve the problems of high cost and large dosage, and achieve the effect of simple composition, low toxicity, safety and no side effects

Inactive Publication Date: 2017-01-04
INFINITUS (CHINA) CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, this traditional Chinese medicine composition has many components, and each component restri

Method used

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  • Traditional Chinese medicine composition capable of diminishing inflammation and easing pain and preparation method thereof
  • Traditional Chinese medicine composition capable of diminishing inflammation and easing pain and preparation method thereof
  • Traditional Chinese medicine composition capable of diminishing inflammation and easing pain and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0050] Preparation of the extract of Silica scutellaria: crushed Sismus sativa, passed through a 10-mesh sieve, weighed 5kg, extracted twice in a water bath at 50°C, each time the solvent was 50L of water, the extract was allowed to stand overnight, and then filtered with suction. The water extract is passed through a macroporous resin to enrich and purify the extract, and the filtrate is directly applied to D101 resin with a diameter of 17cm and a column volume of 26L, and is eluted with (1) 10%, 20%, 30%, and 95% ethanol, each gradient elution 3 column volumes, each column volume is 26L; (2) 30% elution, 95% enrichment, each elution is 3 column volumes, each column volume is 26L. After the sample effluent was rotary evaporated and dried, a total of 29.89 g of the extract of Siberia chinensis was obtained.

Embodiment 2

[0052] Preparation of dried ginger extract: Dried ginger slices were pulverized and passed through a 10-mesh sieve, weighed 3 kg, ultrasonically extracted in 750 L of 70% ethanol water for 15 minutes, and the filtrate was dried to obtain a total of 121.8 g of dried ginger extract.

Embodiment 3

[0054] Preparation of Sophora flavescens extract: crush Sophora flavescens and pass through a 10-mesh sieve, weigh 3kg, add 8 times the amount of water to the medicinal materials, reflux extraction for 2 hours, extract 3 times, combine the extracts, filter with suction, and evaporate to dryness to obtain Sophora flavescens The total extract is 241.8g.

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Abstract

The invention relates to a traditional Chinese medicine composition capable of diminishing inflammation and easing pain. The traditional Chinese medicine composition capable of diminishing inflammation and easing pain is prepared from the following ingredients: a siegesbeckia orientalis extract, a dried ginger extract and a flavescent sophora root extract in weight ratio of 1-4 to 2-5 to 6-10. The invention also relates to a preparation method of the traditional Chinese medicine composition capable of diminishing inflammation and easing pain. The preparation method comprises the following steps of: preparing the siegesbeckia orientalis extract, the dried ginger extract and the flavescent sophora root extract; mixing water, a thickening agent and a liquid preservative so as to a phase A; adding the siegesbeckia orientalis extract, the dried ginger extract and the flavescent sophora root extract into butanediol so as to obtain a phase B; dissolving the phase B with the phase A, then adding an emollient and grease, and finally adding a PH regulator to regulate the PH value, and stirring sufficiently, thereby obtaining an ointment. Compared with the prior art, the traditional Chinese medicine composition provided by the invention is precise and appropriate in medicine compatibility, rapid in effect taking, safe and free from toxic and side effects, is capable of obviously reducing the expression of individual IL-1 beta, TNF-alpha, COX2 and NF-kappaB, has obvious efficacies of diminishing inflammation and easing pain, and achieves an effect of nursing muscles and joints.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to an anti-inflammatory and analgesic traditional Chinese medicine composition and a preparation method of the traditional Chinese medicine composition. Background technique [0002] Muscle soreness is the consequence of physiological changes such as the accumulation of metabolic waste, muscle cramps, and connective tissue damage, and is closely related to the inflammatory response. Due to mechanical damage, chondrocyte repair disorder, and changes in the extracellular environment, bone and joint pain can also occur, and it is mainly related to inflammatory responses (expression of inflammatory genes and release of inflammatory mediators). [0003] Regarding the generation of pain, the inflammation hypothesis holds that pain is a series of inflammatory reactions caused by mechanical injury, in which calcium ions play a trigger role. Inflammatory cells and the i...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/06A61P29/00A61P19/08A61P21/00
CPCA61K36/489A61K9/06A61K36/28A61K36/9068A61K47/14A61K47/32A61K2236/331A61K2236/333A61K2236/39
Inventor 高雅倩唐健肖蕾
Owner INFINITUS (CHINA) CO LTD
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