A centrifugal microfluidic chip and a method for continuously synthesizing janus particles

A microfluidic chip and centrifugal technology, applied in the field of microfluidics, to achieve the effect of improving the synthesis yield
CN106311107BActive Publication Date: 2018-10-23NORTHEASTERN UNIV LIAONING
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
NORTHEASTERN UNIV LIAONING
Publication Date
2018-10-23

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Abstract

A centrifugal microfluidic chip and a method for continuously synthesizing Janus particles; the chip is composed of an upper substrate, a middle substrate and a lower substrate; the upper substrate is provided with an upper central circular hole, an annular liquid pool, and several upper layers The dispersed circular channels are connected with several first-level straight channels; the middle layer substrate is provided with a central circular hole in the middle layer; the lower substrate is provided with a central liquid pool, a lower dispersed circular channel, several second-level straight channels and several third-level straight channels. Straight channel; Method: 1) Fix the centrifugal microfluidic chip on the suction cup of the glue homogenizer; 2) Inject different test solutions into the central liquid pool and the annular liquid tank; open the glue homogenizer and rotate and centrifuge to form a biphasic phase at the outlet of the channel liquid droplets; 3) biphasic liquid droplets are thrown into an external annular liquid pool to form Janus particles; the method of the invention ensures the continuous introduction of test liquids and realizes the continuous synthesis of biphasic particles; the array synthesis channel, high-speed rotation drive liquid and continuous Synthesis, improve the synthesis rate of Janus particles.
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Description

technical field

[0001] The invention belongs to the field of microfluidic technology, in particular to a centrifugal microfluidic chip and a method for continuously synthesizing Janus particles. Background technique

[0002] Janus is a god with two faces in ancient Roman mythology. In 1991, De Gennes used Janus to visualize asymmetric particles for the first time in his Nobel acceptance speech. Because different properties can be exhibited on the same particle, this Janus particle with asymmetric double-sided structure shows better performance than particles with a single property in some application fields, such as emulsion stability, optics, biosensing , drug delivery, and electronics have potential applications.

[0003] The synthesis method based on microfluidic technology has high mass and heat transfer efficiency, easy and accurate control of reaction conditions, fast mixing speed, and low reagent consumption. The use of microfluidic technology in the synthesis of Ja...

Claims

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