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522 results about "Fluid cell" patented technology

Fluid Cells. The ability to image samples in a liquid environment vastly increases the applications of AFM technology. Imaging samples under fluid minimizes surface forces on delicate samples, allows observation of biological specimens under native conditions, and allows real-time observations of samples undergoing electrochemical reactions (ECAFM).

Micro-fluidic chip achieving multi-index detection

The invention discloses a micro-fluidic chip achieving multi-index detection, and relates to the field of micro-fluidic chip medical treatment detection. The micro-fluidic chip achieving multi-index detection comprises a gas control channel layer, an organic macromolecular polymer film layer and a micro-fluid channel layer. All the layers of materials are integrated, bonded and sealed to form the chip structure. The micro-fluidic chip is characterized in that the gas control channel layer comprises a sample inlet hole, a gas outlet hole, two pneumatic micro valves and upper portions of multiple liquid storage pools connected in series; holes are formed in the portions, corresponding to the sample inlet hole, the pneumatic micro valve structures, the liquid storage pools and the gas outlet hole, of the organic macromolecular polymer film; the micro-fluid channel layer is provided with lower portions of the liquid storage pools connected in series, multiple reaction pools, a liquid channel making all the liquid storage pools communicated and a liquid channel making the liquid storage pools and the reaction pools communicated. The micro-fluidic chip is simple in structure and convenient to use, the pneumatic micro valves are utilized for making the liquid storage pools and the reaction pools independent, mutual pollution of liquid among the reaction pools is avoided, the precision of a sample amount is improved, and reliability of detection results is guaranteed.
Owner:GETEIN BIOTECH

Disposable separating chip module for peripheral blood circulating tumor cell and application method of disposable separating chip module

The invention provides a disposable separating chip module for a peripheral blood circulating tumor cell and an application method of the disposable separating chip module. The disposable separating chip module comprises a micro-fluidic chip, a blood sample storage tank, a PBS sample storage tank, a waste liquid storage tank, an enrichment recycling liquid outlet, a connecting guide pipe (1) of the micro-fluidic chip and the blood sample storage tank, a connecting guide pipe (2) of the micro-fluidic chip and the PBS sample storage tank, a connecting guide pipe (3) of the micro-fluidic chip and the waste liquid storage tank, and a connecting guide pipe (4) of the micro-fluidic chip and the enrichment recycling liquid outlet. The invention further provides the application method of the disposable separating chip module. The micro-fluidic chip adopts a dual-inlet and dual-outlet structure and has an erythrocyte removing efficiency of 100%. A clinical blood sample requires no pretreatment process of attenuation or erythrocyte lysis, so that plenty of time for separating operation can be saved, and the activity of the circulating tumor cell after separation and enrichment can be effectively guaranteed.
Owner:SHENZHEN RUISI LIFE TECH CO LTD

Method and apparatus for forming a homeostatic loop employing an aptamer biosensor

A novel architecture solid-state biosensor for label-free detection of vascular endothelial growth factor (VEGF) hybridization is presented. The new device is realized by forming a matrix array of parallel capacitors, thus allowing the realization of low-cost, portable, fully integrated devices. The detection mechanism is based on an electrochemical binding of circulating VEGF to an immobilized VEGF aptamer; whereby binding of these two compounds modulates the threshold voltage of a novel circuit, changing the impedance (capacitance) of the circuit. This novel circuit is further characterized by an electrode coded with a p-Si substrate, enhancing the affinity between the VEGF molecules and the aptamer. An apparatus forming a fluid cell is configured so as to enable the flow for delivering VEGF samples onto the active surface of the chip. The device has an array of parallel capacitors which act as an integrated, individual counter-electrode, computational apparatus which employs the sensory output over the time domain so as to enable detection, reporting and formation of a homeostatic loop for VEGF measurements. Moreover, this detector is able to provide an accurately measured and quantifiable rate of change of the VEGF molecules in-vivo, providing real time feedback of this important biomarker which may be used to measure response of the tumor to delivered chemotherapeutic agents and biological response modifiers (BRMs) for the purpose of determining tumor burden.
Owner:SENSOR KINESIS

Thermoelectric power generation type high-temperature drilling fluid cooling and circulating system

A thermoelectric power generation type high-temperature drilling fluid cooling and circulating system comprises a refrigerating unit, a refrigerating unit pump, a first valve, a second valve, a cooling fluid loading box, a cooling fluid delivering pump, a heat exchanger, a steam-turbine generator, an electricity storage box, electric equipment, a condenser, a well, a drilling fluid pond, a first drilling fluid delivering pump and a second drilling fluid delivering pump; the first drilling fluid delivering pump is positioned between the well and the drilling fluid pond, and pumps the high-temperature drilling fluid upwards returning from the well to the drilling fluid pond; and the second drilling fluid delivering pump is positioned between the drilling fluid pond and the heat exchanger, and delivers the high-temperature drilling fluid to the heat exchanger. By the heat exchanger, the high-temperature drilling fluid and the cooling fluid are subjected to heat exchange, the exchanged cooling fluid becomes high-temperature and high-pressure gas which enters the steam-turbine generator to drive the generator to generate power, and the generated electric energy is stored in the electricity storage box and supplies power for the electric equipment. After the high-temperature drilling fluid becomes low-temperature drilling fluid by exchange through the heat exchanger, the low-temperature drilling fluid enters the well through a sixth pipeline.
Owner:JILIN UNIV

Electroslag smelting casting device with additional electromagnetic stirring and method

The invention relates to an electroslag casting device additionally provided with electromagnetic stirring and a method thereof. The electroslag casting device belongs to the technical field of special steel electroslag metallurgy and comprises a crystallizer, a crystallizer water jacket and an electromagnetic stirrer; an annular magnet is sleeved on the outer wall of the crystallizer and positioned at the middle-upper part of the crystallizer, a loop is wound on an iron core of the annular magnet, an electromagnetic stirrer water jacket is arranged at the periphery of the annular electromagnet, and the electromagnetic stirrer water jacket is communicated with the crystallizer water jacket; a melting consumable electrode forms molten steel drops which then enter a slag layer; the molten steel drops fall down in a spiral line way in the slag layer under the action of the rotary electromagnetic field and then enter a steel ingot liquid tank; the steel ingot liquid tank raises continuously and also enters into an effective magnetic field action region of the electromagnetic stirrer; and meanwhile, electric current in the molten steel is acted with the rotary magnetic field to produce the electromagnetic force which then drives the molten steel to rotate. The invention has simple equipment, and has the obvious functions of improving the surface quality, the subsurface quality and the solidifying tissue of a casting blank and the isometric crystal ratio, and lightening the internal defects, such as the center segregation, the center looseness, and the like.
Owner:NORTHEASTERN UNIV

Paper document deacidification device and method

ActiveCN105544299AThe process is non-toxic and harmlessAvoid damageOld paper after-treatmentEngineeringPaper document
The invention provides a paper document deacidification device and method. The device comprises a controller, a base, a document bracket, a paper detection device, an atomizing spraying device, a page turning device, a feed liquid pool, a hydrosolvent deacidification liquid defined amount control device and hydrosolvent deacidification liquid delivery pipelines, wherein the document bracket is arranged on the base, the paper detection device and the atomizing spraying device are arranged on the document bracket and located on the two sides of the document bracket respectively, and the page turning device is arranged in the middle of the document bracket; the hydrosolvent deacidification liquid defined amount control device is arranged between the atomizing spraying device and the feed liquid pool, the hydrosolvent deacidification liquid defined amount control device is connected with the atomizing spraying device and the feed liquid pool through the hydrosolvent deacidification liquid delivery pipelines respectively, the paper detection device, the hydrosolvent deacidification liquid defined amount control device, the atomizing spraying device and the automatic page turning device are all electrically connected with the controller, and a paper pH detector is arranged on the paper detection device. In this way, uniform deacidification of the whole paper document is achieved, alkali stock is uniform, and deformation and damage of the document are avoided.
Owner:NANJING MUSEUM

Ground-type tidal Irrigation system

The invention discloses a ground-type tidal Irrigation system, which is used for irrigating potted plants with water or nutrient solution and comprises an upper water supply and drainage trench which is arranged at the upper part of a seedbed, a lower water supply and drainage pipeline which is arranged below the seedbed and is connected with the upper water supply and drainage trench, a water supply system and a water drainage system which are respectively connected with the lower water supply and drainage pipeline and a nutrient solution pond, and a comprehensive control system which are connected with the water supply system, the water drainage system and the nutrient solution pond. An ultraviolet ozone disinfection system and an electric floor heating system are additionally arranged in the system. The ground-type tidal Irrigation system can simulate tide rising and tide falling to irrigate the plants from roots, realizes the continuous cyclic use of the nutrient solution through the ultraviolet ozone disinfection system, reduces the spreading of soil-borne diseases and improves the production benefit of crops; good ground temperature can be provided for the growth and the irrigation of the crops in cold seasons and the situation that the crops grow slowly is avoided; and the comprehensive control system can realize the comprehensive control of the irrigation system, the disinfection system and the electric floor heating system to enable the application to be more convenient and faster.
Owner:BEIJING RES CENT OF INTELLIGENT EQUIP FOR AGRI
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