Medicine used for preventing and treating mycotic, trichomonas and senile vaginitis and preparation method thereof

A technology for trichomoniasis and senile vaginitis, which is applied in the field of trichomoniasis and senile vaginitis medicines and fungal prevention, can solve the problems of poor drug adhesion, large side effects, poor sustained release and absorption, etc., and it is easy to achieve the reaction conditions , The preparation method is easy to operate

Active Publication Date: 2017-04-26
HUBEI JINGGENG BIOLOGICAL ENG CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the market for gynecological external use products can be said to be innumerable. There are many western medicine products. Good, and basically destroy the acid-base balance of the vagina, and these products have poor drug adhesion and poor slow-release absorption

Method used

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  • Medicine used for preventing and treating mycotic, trichomonas and senile vaginitis and preparation method thereof

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preparation example Construction

[0053] Specifically, when the medicine is a lotion, the present invention also provides a preparation method of the lotion, comprising the following steps:

[0054] Mixing the Cnidium Fructus Cnidii Extract and Sophora Sophora Sophora Extract with water and then sieving to obtain the extract solution;

[0055] Mix fucoidan oligosaccharides and chitosan oligosaccharides with water and sieve to obtain sugar solution;

[0056] Mix peppermint oil, pine essential oil and tea tree essential oil to get a blended essential oil;

[0057] mixing the sugar solution with the mixed essential oil to obtain an essential oil-sugar mixed solution;

[0058] Mixing lavender essential oil, plant lactic acid, the extract solution, the essential oil-sugar mixture, and water 2.5 to 3.5 times the mass of the total active components to obtain a lotion precursor;

[0059] Under vacuum conditions, the lotion precursor is mixed with ozonated oil, and the pH value is adjusted to 4.0 to obtain a lotion. ...

Embodiment 1

[0093] Take 5g of Fructus Cnidii extract, 5g of Sophora flavescens extract and 10g of water and stir at 100r / min for 3 minutes and pass through a 100 mesh sieve to obtain the extract solution; take 20g of fucoidan oligosaccharide and 5g of chitosan oligosaccharide and 28g of water at 100r / min Stir for 3 minutes and pass through a 90-mesh sieve to obtain sugar liquid; take 4.5g of peppermint oil and 40g of pine essential oil and stir at 100r / min for 5 minutes, then add 50g of tea tree essential oil and stir for 10 minutes at 120r / min to obtain a mixed essential oil; Stir the sugar solution and the obtained mixed essential oil at 120r / min for 8 minutes to obtain an essential oil-sugar mixture; take 1g of lavender essential oil, 30g of plant lactic acid, the obtained extract solution, essential oil-sugar mixed solution and 600g of water and stir at 100r / min After 15 minutes, a lotion precursor was obtained; the obtained lotion precursor was stirred with 20 g of ozonated oil at 150...

Embodiment 2

[0095] Take 50g of Fructus Cnidii extract, 20g of Sophora flavescens extract and 84g of water and stir at 120r / min for 5 minutes, then pass through a 110 mesh sieve to obtain the extract solution; Stir for 4 minutes and pass through a 100-mesh sieve to obtain sugar liquid; take 1g of peppermint oil and 120g of pine essential oil and stir at 100r / min for 3 minutes, then add 10g of tea tree essential oil and stir at 100r / min for 8 minutes to obtain a mixed essential oil; solution and the obtained mixed essential oil were stirred at 100r / min for 10 minutes to obtain an essential oil-sugar mixed solution; 20 g of lavender essential oil, 10 g of plant lactic acid, the obtained extract solution and essential oil-sugar mixed solution and 1250 g of water were stirred at 100 r / min for 10 minutes Minutes to obtain a lotion precursor; the obtained lotion precursor was stirred at -70KPa with 60g of ozonated oil at 200r / min for 10 minutes, and the pH value was adjusted to 4.0 to obtain a lo...

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Abstract

The invention provides a medicine used for preventing and treating mycotic, trichomonas and senile vaginitis. The medicine is prepared form, by weight, 2-15 parts of alginate oligosaccharide, 0.5-15 parts of chitosan oligosaccharide, 2-12 parts of ozonide oil, 1-12 parts of baeckea frutescens essential oil, 1-15 parts of tea tree essential oil, 0.5-5 parts of fructus cnidii extractive, 0.5-6 parts of radix sophorae flavescentis extractive, 0.1-5 parts of lavender essential oil, 0.1-4.5 parts of mint oil and 1-6 parts of plant lactic acid. The invention further provides the preparation method through which the medicine is prepared into lotion, gels and suppository. The effective rates of the medicine used for preventing and treating mycotic, trichomonas and senile vaginitis treating mycotic, trichomonas and senile vaginitis can reach up to 100%, 98.8% and 100% respectively.

Description

technical field [0001] The invention belongs to the field of medicaments, in particular to a medicament for preventing and treating fungal, trichomonas and senile vaginitis. Background technique [0002] Mycotic vaginitis or candidal vaginitis is vulvovaginal candidiasis (VVC), which is a common multiple vulvovaginal inflammatory disease caused by Candida. The typical symptom of candidal vaginitis is vulvar itching , and the symptoms of pruritus are mild and sometimes severe, and sometimes stop. When the itching is severe, it is restless, and it is difficult to sleep and eat. When the inflammation is severe, dysuria and sexual intercourse may also occur. Increased leucorrhea is another main symptom of this disease. Leucorrhea is generally very thick, in the form of bean dregs or milk curds. Fetal safety must be considered in the treatment of complicated vulvovaginal candidiasis and vulvovaginal candidiasis during pregnancy. [0003] Vaginal trichomoniasis is a sexually tra...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/61A61K9/06A61K47/32A61K9/02A61P15/02A61P31/10A61P33/02A61K33/00A61K31/722A61K31/702A61K31/19
CPCA61K9/0034A61K9/02A61K9/06A61K31/19A61K31/702A61K31/722A61K33/00A61K36/234A61K36/489A61K36/53A61K36/534A61K36/61A61K47/32A61K2236/331A61K2300/00
Inventor 陈耕
Owner HUBEI JINGGENG BIOLOGICAL ENG CO LTD
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