Functional flexible electrode and preparation method thereof

A flexible electrode, functionalized technology, applied in cable/conductor manufacturing, conductive layers on insulating carriers, circuits, etc., can solve problems such as inability to achieve multi-channel stimulation or information acquisition functions, shape adaptation and matching, and easily damaged electrodes, etc. Achieve the effects of diversified preparation methods, high reliability and good safety

Active Publication Date: 2017-04-26
SHENZHEN INST OF ADVANCED TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, such wearable and implantable devices all have the same problem: shape adaptation and matching
Especially for these implantable devices, in case of failure and danger, they can only be removed and replaced by surgery, which will cause greater trauma to the patient
What's more, some implanted devices, such as artificial retina, will be combined with human tissue after implantation, so it is not easy to replace
[0003] In the early days, the shape change of flexible electrodes was realized by pressure-induced deformation through annealing, but it was easy to damage expensive electrodes (Survey of Ophthalmology, 2002, 47, 335-356)
Recently, the Charles M. Lieber research group of Harvard University developed an injectable metal mesh electrode, which will automatically expand after being injected into the living body. However, the expansion of the electrode is only based on the release of the internal stress of the metal mesh electrode, which may lead to Tissue damage (Nature Nanotechnology, 2015, 10, 629-636), and the entire metal network can only be used as a single stimulation or information collection unit, and cannot achieve multi-channel stimulation or information collection functions

Method used

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Embodiment 1

[0032] In an embodiment of the functionalized flexible electrode of the present invention, the flexible electrode includes a flexible substrate, the material of the flexible substrate is polydimethylsiloxane, and one side of the flexible substrate is provided with an electrode material, The other side of the flexible substrate is provided with functionalized material. The preparation method of the functionalized flexible electrode comprises the following steps:

[0033] (1) providing a flexible electrode with a polydimethylsiloxane substrate;

[0034] (2) After the surface of the polyimide (PI) substrate is treated by plasma, it is placed in the atmosphere of vinyltrichlorosilane, and the graft is deposited on the surface of the polyimide substrate by chemical vapor deposition. upper double bond; 0.5g N-isopropylacrylamide, 0.005g N,N-dimethylacrylamide, 10μL ultraviolet photoinitiator dialkoxyacetophenone, and 1mL water were mixed and ultrasonically dispersed, using a specif...

Embodiment 2

[0037] In an embodiment of the functionalized flexible electrode according to the present invention, the flexible electrode includes a flexible substrate, the material of the flexible substrate is parylene, and one side of the flexible substrate is provided with an electrode material, and the flexible substrate is provided with an electrode material. The other side of the substrate is provided with functionalized material. The preparation method of the functionalized flexible electrode comprises the following steps:

[0038] (1) providing a flexible electrode with a parylene substrate;

[0039] (2) 3 g of polyglycolic acid was added to 20 g of dimethyl amide (DMF), and the solution was mechanically stirred until the solution was transparent to obtain an electrospinning solution; the obtained spinning solution was loaded into a liquid storage device, and the spinning needle and A spinning voltage of 20 KV was applied between a flexible electrode based on parylene as the receiv...

Embodiment 3

[0042] In an embodiment of the functionalized flexible electrode of the present invention, the flexible electrode includes a flexible substrate, the material of the flexible substrate is polyimide, and one side of the flexible substrate is provided with an electrode material, and the flexible substrate is provided with an electrode material. The other side of the substrate is provided with functionalized material. The preparation method of the functionalized flexible electrode comprises the following steps:

[0043] (1) providing a flexible electrode with a polyimide substrate;

[0044] (2) Add 3g of polylactic acid, 0.5g of polyethylene glycol, and 0.2g of gold nanoparticles into the beaker, heat it to a molten state at 160 ° C and mix it evenly, pour the molten liquid into a specific mold, and the bottom of the mold is flexible The surface of the polyimide (PI) substrate of the electrode is obtained, that is, a functionalized flexible electrode with shape memory effect is o...

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Abstract

The invention provides a functional flexible electrode which comprises a flexible substrate, wherein an electrode material is arranged on one surface of the flexible substrate and a functional material is arranged on the other surface of the flexible substrate. A preparation method for the functional flexible electrode provided by the invention is various; the shape change can be realized through the stimulation of temperature, humidity, light, and the like; the mode is various; the control is convenient; and a firm basis is established for the application of the functional flexible electrode in the wearing and implantable medical fields.

Description

technical field [0001] The invention relates to a flexible electrode, in particular to a functionalized flexible electrode and a preparation method thereof. Background technique [0002] In recent years, with the aggravation of aging, the incidence of various chronic diseases such as hearing and vision has become higher and higher, especially in China, as an increasingly aging country, the current aging population has reached 200 million. The resulting social and family problems will become increasingly serious. Fortunately, in the past 30 years, the wearable and implantable medical device industry has developed rapidly and achieved remarkable results: from wearable ECG and EEG monitoring devices, to implantable cardiac pacemakers, Cochlear implants, artificial retinas, various implantable electrodes (for the treatment of Parkinson's disease, epilepsy and other diseases), etc. Relevant products have been very effective in solving problems such as hearing and visual impairm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): H01B5/14H01B13/00
CPCH01B5/14H01B13/00H01B13/0016H01B13/003
Inventor 杜学敏崔欢庆王娟吴天准
Owner SHENZHEN INST OF ADVANCED TECH
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